A5036809180- Climate Change and Health Impacts
- RNA modifications and cancer
- Epigenetics and DNA Methylation
- Air Quality and Health Impacts
- Cancer, Hypoxia, and Metabolism
- Clinical practice guidelines implementation
- Cytokine Signaling Pathways and Interactions
- Meta-analysis and systematic reviews
- Cholesterol and Lipid Metabolism
- Gallbladder and Bile Duct Disorders
- Liver Diseases and Immunity
- Pediatric Hepatobiliary Diseases and Treatments
- Ocular Diseases and Behçet’s Syndrome
- Mosquito-borne diseases and control
- Rheumatoid Arthritis Research and Therapies
- Systemic Lupus Erythematosus Research
- Oral Health Pathology and Treatment
- Viral Infections and Vectors
- Health Systems, Economic Evaluations, Quality of Life
- Cancer-related gene regulation
- Peptidase Inhibition and Analysis
- Genomic variations and chromosomal abnormalities
- Radiation Dose and Imaging
- Phagocytosis and Immune Regulation
- interferon and immune responses
Tianjin First Center Hospital
2024
Tianjin Medical University
2024
Lanzhou University
2015-2023
Wenzhou Medical University
2023
First Affiliated Hospital of Zhengzhou University
2023
Hospital of Stomatology, Sun Yat-sen University
2019
Stomatology Hospital
2019
Sun Yat-sen University
2019
The Affiliated Yongchuan Hospital of Chongqing Medical University
2017
Chongqing Medical University
2017
Amyloid-β (Aβ) is a major constituent of drusen, which hallmark early AMD. The purpose this study was to investigate whether enhancement ACE2, an important component the protective angiotensin-converting enzyme 2 (ACE2)/Ang-(1-7)/Mas axis renin angiotensin system (RAS), ameliorates Aβ-induced inflammatory response in human RPE cells.Annexin-V FITC/propidium iodide assay for detecting apoptosis rate used determine optimum concentration and incubation time Aβ1-42. ACE2 plasmid transfected into...
Osteoradionecrosis of the jaws (ORNJ) is among most serious oral complications head and neck cancer treatment with radiation therapy. This study aimed to examine level symptom distress interference ORNJ in patients China.A cross-sectional was conducted profile patient reported severity. Ninety-five hospitalized were recruited. Participants completed MD Anderson Symptom Inventory-Head Neck Module-Chinese version.The percentage participants who that they experienced at least one type 97.9%,...
Abstract Haplotype‐based noninvasive prenatal diagnosis (NIPD) is applicable for various recessive single‐gene disorders in proband families. However, a comprehensive exploration of critical factors influencing the assay performance, such as fetal fraction, informative single nucleotide polymorphism (SNP) count, and recombination events, has yet to be performed. It identify key affecting NIPD including its accuracy success rate, their impact on clinical diagnostics guide practice. We...
<title>Abstract</title> <bold>Objective</bold> Cinobufacini exhibits significant anti-cancer effects on various malignant tumors, particularly demonstrating outstanding efficacy against hepatocarcinoma. The anti-tumor of primarily manifest as inhibition tumor cell proliferation, cycle arrest, and modulation immune responses. Bufalin, the most potent active component in Cinobufacini, requires further exploration its mechanisms. We aim to elucidate potential mechanisms Bufalin treating...
11-19 months) from symptom appearance to the first patient visit hospital.Sequence analysis revealed that frameshift mutation 327del C (p.Gly39Alafs*26) in exon 1 affected all family members, but not healthy individuals or 16 unrelated controls.Members without gene showed no clinical manifestation of VHL disease.We detected a conserved novel members contributes VHL.DNA is advantageous for diagnosis.We developed quick and reliable method diagnosis.
Primary biliary cholangitis (PBC) is a rare autoimmune liver disease with few effective treatments and poor prognosis, its incidence on the rise. There an urgent need for more targeted treatment strategies to accurately identify high-risk patients. The use of stochastic survival forest models in machine learning innovative approach constructing prognostic model PBC that can improve prognosis by identifying patients treatment.
Background: Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory arthropathy. Recommendations for RA, specifically on pharmacotherapy, are essential in clinical practice. However, the direction and strength of recommendations controversial across current practice guidelines (CPGs) RA. Objective: To systematically analyze consistency regarding pharmacotherapy RA CPGs. Methods: 11 electronic databases websites were comprehensively searched from inception to 14 March 2022, identify...
In China, the number of patients diagnosed with gastric cancer remains high and best treatment is early detection treatment. However, large-scale endoscopic screening cannot be performed in China. The most appropriate approach to first screen high-risk groups then perform testing on that basis. We enrolled 25,622 asymptomatic participants from a free program for individuals aged 45-70 years minimum living security population (MLGC) initiated by Taizhou city government 2019. Participants...
Abstract Background An increasing number of systematic reviews (SRs) in the environmental field have been published recent years as a result global concern about health impacts air pollution and temperature. However, no study has assessed compared methodological reporting quality SRs on effects pollutants extreme temperatures. This aims to assess compare ambient Methods PubMed, Embase, Cumulative Index Nursing Allied Health Literature (CINAHL), Cochrane Library, Web Science, Epistemonikos...