Ayşen Gökyiğit

ORCID: 0000-0003-4914-1712
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About
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Research Areas
  • Epilepsy research and treatment
  • Neuroscience and Neuropharmacology Research
  • Pharmacological Effects and Toxicity Studies
  • EEG and Brain-Computer Interfaces
  • Virology and Viral Diseases
  • Glycogen Storage Diseases and Myoclonus
  • Genetics and Neurodevelopmental Disorders
  • Metabolism and Genetic Disorders
  • Ion channel regulation and function
  • Autoimmune Neurological Disorders and Treatments
  • Neurological disorders and treatments
  • Syphilis Diagnosis and Treatment
  • Immunodeficiency and Autoimmune Disorders
  • Immune responses and vaccinations
  • Mitochondrial Function and Pathology
  • Psychosomatic Disorders and Their Treatments
  • Sleep and Wakefulness Research
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Ion Transport and Channel Regulation
  • Restless Legs Syndrome Research
  • Ocular Diseases and Behçet’s Syndrome
  • Viral Infections and Immunology Research
  • Obsessive-Compulsive Spectrum Disorders
  • SARS-CoV-2 and COVID-19 Research
  • Transcranial Magnetic Stimulation Studies

Istanbul University
2011-2021

Antalya Eğitim ve Araştırma Hastanesi
2014

Neurology, Inc
2001-2007

Our aim was to assess the long-term follow-up of juvenile myoclonic epilepsy (JME), with an emphasis on course seizures.We enrolled 48 patients JME (29 F, 19 M; aged 39.9 +/- 9.5 years) followed up for a mean 19.6 5.7 years. The remission 5 years and relapses were evaluated all seizure types changes in severity/frequency myoclonia systematically questioned. clinical EEG features, antiepileptic drug (AED) treatment regimen, systemic psychiatric comorbid diseases evaluated.We found benign...

10.1212/01.wnl.0000313148.34629.1d article EN Neurology 2008-05-27

Neuronal antibodies have been identified in patients with seizures as the main or sole symptom. Our aim was to investigate prevalence of these autoantibodies focal epilepsy unknown cause (FEoUC) and group having mesial temporal lobe hippocampal sclerosis (MTLE-HS).We studied anti-neuronal consecutive adult diagnosed FEoUC MTLE-HS our center. The clinical laboratory features antibody-positive were compared those seronegative patients. responses therapy also investigated.Sera from 81 tested....

10.1111/epi.12528 article EN Epilepsia 2014-02-06

We studied 36 patients (24 males, 12 females), all of whom had definite subacute sclerosing panencephalitis with typical periodic complexes in their electroencephalograms and increased titers measles antibody serum cerebrospinal fluid. Their clinical laboratory findings on admission were reviewed retrospectively. The age at onset symptoms varied from 4 to 23 years. average disease was 13.1 +/- 4.18 mean the duration infection 9 Unusual symptoms, especially early periods disease, included...

10.1177/088307380201700106 article EN Journal of Child Neurology 2002-01-01

<h3>Objective</h3> Our aim was to investigate the prevalence of neuronal autoantibodies (NAbs) in a large consecutive series with mesial temporal lobe epilepsy hippocampal sclerosis (MTLE-HS) and elucidate clinical laboratory clues for detection NAbs this prototype frequent, drug-resistant syndrome. <h3>Methods</h3> Consecutive patients diagnosed MTLE fulfilling MRI criteria HS were enrolled. The sera various control groups (80 subjects) tested eight after ethical approval signed consents....

10.1136/jnnp-2016-313146 article EN Journal of Neurology Neurosurgery & Psychiatry 2016-05-05

Our aim is to outline the clinical and electroencephalographic (EEG) features of patients with hot water epilepsy (HWE), a rare unique form reflex epilepsy.Twenty-one HWE, seen in our clinic until 1999, were studied. Male outnumbered female subjects ratio 3:1. The age at onset seizures ranged from 19 months 27 years (mean onset, 12 years).The main factors precipitating bathing and/or pouring over head. Six reported self-induction, either by increasing heat or amount recalling earlier...

10.1046/j.1528-1157.2001.31000.x article EN Epilepsia 2001-09-01

Betül Tekin Güveli, Rasim Özgür Rosti, Alper Güzeltaş, Elif Bahar Tuna, Dilek Ataklı, Serra Sencer, Ensar Yekeler, Hülya Kayserili, Ahmet Dirican, Nerses Bebek, Baykan, Ayşen Gökyiğit, and Candan Gürses. Clin Psychopharmacol Neurosci 2017;15:19-27. https://doi.org/10.9758/cpn.2017.15.1.19

10.9758/cpn.2017.15.1.19 article TR Clinical Psychopharmacology and Neuroscience 2017-01-25

Summary Continuous, generalized 2.5 to 3.5‐Hz spikewave (SW) discharges were evident in an EEG performed 13 h after a first seizure associated with viral illness, 8‐year‐old girl. On eye opening, the abnormality was suppressed and replaced by delta activity brief spike‐wave paroxysms. No alteration consciousness seizures or behavioral abnormalities accompanied findings. Based on EEG, she diagnosed as having “diffuse electrical status,” rare phenomenon that occurs during wakefulness without...

10.1111/j.1528-1157.1995.tb00982.x article EN Epilepsia 1995-02-01

We report the first case of an autoimmune thyroid encephalopathy presenting with multifocal motor status epilepticus. A 37-year-old female patient was admitted seizures intractable to intravenous epilepticus treatments, asymmetrical quadriparesis, truncal ataxia and continuous semi-rhythmical jerks. Pathological signal alterations were detected in both precentral cortices MRI examination. Autoimmune thyroiditis diagnosed after radiological examinations gland function tests. Seizures promptly...

10.1177/155005940603700308 article EN Clinical EEG and Neuroscience 2006-07-01

To outline the clinical characteristics of seizures in our large series Behçet disease (BD) patients with neurologic involvement.All files 223 neuro-BD were evaluated retrospectively, and group clearly documented was included current study. Clinical characteristics, EEG, neuroimaging cerebrospinal fluid findings reevaluated, classified according to new proposed criteria International League Against Epilepsy. On excluding whom due possible seizure-provoking factors, that appeared during a...

10.1046/j.1528-1157.2002.01102.x article EN Epilepsia 2002-08-01

Purpose: The purpose of this study was to analyze electrophysiological properties four main stages ictal patterns patients with operated temporal lobe epilepsy related hippocampal sclerosis. Methods: We included 48 epilepsy–hippocampal Seizures were classified according their and surgical outcomes as seizure-free not seizure-free. EEGs artifacts at the beginning analyzed separately. Results: most frequent type onset rhythmic theta/alpha activity, which correlated group, whereas "switch...

10.1097/wnp.0b013e31829d7482 article EN Journal of Clinical Neurophysiology 2013-08-01

Summary: Purpose: To describe the characteristics of patients with typical absence seizures (TASs), consistently triggered by photosensitivity. Methods: Consecutive having TAS induced intermittent photic stimulation were included in study. All clinical parameters, EEG, and video‐EEG data assessed during long‐term follow‐up. Statistical analyses performed SPSS 10.0 software. Results: Nine female two male a mean age at onset 14 ± 5.9 years (range, 7–27 years) follow‐up 9 7.56 had...

10.1111/j.0013-9580.2005.67303.x article EN Epilepsia 2005-01-01

ABSTRACT Three patients with neurosyphilis are reported. The first and third presented convulsive status epilepticus the second non‐convulsive after penicillin administration. In all cerebrospinal fluid serum Venereal Disease Research Laboratory Test (VDRL) Treponema Pallidum hemagglutination (TPHA) or fluorescent treponemal antibody absorption test (FTA‐ABS) were positive, but HIV serology was negative. Their EEGs showed periodic, lateralized, epileptiform discharges (PLEDs) just SE. had no...

10.1684/epd.2007.0058 article EN Epileptic Disorders 2007-03-01
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