A5035211287- Asthma and respiratory diseases
- Respiratory and Cough-Related Research
- Drug-Induced Adverse Reactions
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Pediatric health and respiratory diseases
- Chemotherapy-related skin toxicity
- Cancer, Hypoxia, and Metabolism
- Autoimmune Bullous Skin Diseases
- Contact Dermatitis and Allergies
- Ultrasound in Clinical Applications
- Inhalation and Respiratory Drug Delivery
- Glioma Diagnosis and Treatment
- Urticaria and Related Conditions
- Neuroblastoma Research and Treatments
- Inflammatory mediators and NSAID effects
- Food Allergy and Anaphylaxis Research
- Colorectal Cancer Treatments and Studies
- Hemophilia Treatment and Research
- Pleural and Pulmonary Diseases
- Allergic Rhinitis and Sensitization
- Respiratory Support and Mechanisms
Hacettepe University
2023-2025
Hacettepe University Hospital
2024
Bakırçay Üniversitesi
2021
Background: The data on subphenotypes and treatment responses to biologicals in late-onset asthma (LOA) is limited. This study aims compare the clinical characteristics severe patients receiving biological treatments, categorized into early-onset (EOA) LOA groups. Methods: Patients treated with omalizumab or mepolizumab for at least six months a tertiary care adult allergy clinic between December 2015 2023 were included. persistent respiratory symptoms starting age ≥40 years as LOA, while...
Non-steroidal anti-inflammatory drug (NSAID)-exacerbated respiratory disease (N-ERD) can be difficult to diagnose due the heterogeneity of phenotypes and a lack validated in vitro tests. This study aimed provide better understanding course N-ERD disease, analyze whether there was delay clinical diagnosis, explore factors that might cause diagnostic delay. observational, cross-sectional, included patients aged over 18. The time taken by clinicians recorded as clinician diagnosis time, while...
Introduction: Surgical interventions can trigger angioedema attacks in hereditary (HAE). The aim of this study was to assess the incidence perioperative and identify associated risk factors. Methods: This retrospective included HAE patients diagnosed between 1999 2024 at a tertiary adult allergy clinic. Data on surgical procedures were analyzed. Results: Of 102 patients, 28 excluded due incomplete data, leaving 74 (46 female, 62.2%). Fifty-three underwent 94 surgeries, with most common being...
NSAID-exacerbated respiratory disease (NERD) is characterized by exacerbation of symptoms after NSAID intake. While research for specific treatment options continues in patients who cannot tolerate or are unresponsive to aspirin desensitization (ATAD), biologicals have emerged as a new therapeutic option NERD patients. The aim this study was compare the quality life, and sinonasal outcomes treated with ATAD biologicals.Patients been followed up at tertiary care allergy center receiving least...
Procarbazine is an oral chemotherapeutic agent used in the treatment of brain malignancies and associated with hypersensitivity reactions. In case grade 4 reactions, rechallenge should be avoided, replaced, unless curative, which application a desensitization protocol considered. We present successful procarbazine anaphylaxis.
<b><i>Introduction:</i></b> Non-steroidal anti-inflammatory drug-exacerbated respiratory disease (N-ERD) is heterogeneous in both phenotypes and endotypes. Due to insufficient head-to-head comparison studies, it hard decide which biological initiate. This study aimed compare the efficacy of omalizumab mepolizumab can be used treatment patients with severe eosinophilic asthma diagnosed N-ERD. <b><i>Methods:</i></b> The population this...
Being stung by Hymenoptera species can cause life-threatening anaphylaxis. Although venom immunotherapy (VIT) seems to be the most effective treatment, its long-term efficacy, and risk factors for adverse events remain unclear.
Amaç: Plevral sıvıların tanısında, transüda (T)–eksüda (E) ayrımının yapılması önemlidir. Bu çalışmanın amacı, Light kriterleri ile plevral sıvı kolesterol düzeyini içeren tekli, ikili ve üçlü testlerin, T-E ayırımındaki duyarlılık özgüllüğünü belirlemektir.
 Gereç Yöntem: Çalışmaya nedeniyle başvuran 145 hasta dâhil edildi. düzeyi (PSKD) ≥45 mg/dL (tekli test); PSKD veya LDH >kan normal LDH’sının %45 (ikili protein >2,9 g/dL, mg/dL, (üçlü test) olarak tanımlandı. Kesin tanıya...