A5002129691- Medicinal Plants and Neuroprotection
- Neuroinflammation and Neurodegeneration Mechanisms
- Cholinesterase and Neurodegenerative Diseases
- Neurological Disease Mechanisms and Treatments
- Ginger and Zingiberaceae research
- Alzheimer's disease research and treatments
- Electrochemical Analysis and Applications
- Advanced Chemical Sensor Technologies
- COVID-19 and Mental Health
- Genomics, phytochemicals, and oxidative stress
- Ginseng Biological Effects and Applications
- COVID-19 Pandemic Impacts
- Tea Polyphenols and Effects
- Mangiferin and Mango Extracts
- Neuroscience and Neural Engineering
- Curcumin's Biomedical Applications
- Biological and pharmacological studies of plants
- Coffee research and impacts
- Employment and Welfare Studies
University of Phayao
2018-2023
Naresuan University
2010-2021
Maharat Nakhon Ratchasima Hospital
2012
Coffee pulp (CP) is a coffee byproduct that contains various active ingredients, namely, chlorogenic acid (CGA) and caffeine. These compounds show several benefits, including antihyperlipidemia, antioxidants, anti-inflammation. However, the anti-inflammatory properties of Coffea extract (CPE) are unknown. This work determined impact CPE on lipopolysaccharide (LPS)-activated murine macrophage cells molecular mechanism behind this action. RAW 264.7 were exposed to varying doses with or without...
Bacopa monnieri (L.) Wettst. (Brahmi in India and Thailand) is an ayurvedic dementia treatment, but its effect on cerebral blood flow (CBF) still unknown. We sought to test chronic acute effects CBF compared with Ginkgo biloba donepezil. was measured by laser Doppler from rat cortex after 8 weeks of daily oral dosing these drugs. Systolic pressure also using the tail cuff method or via arterial cannulation. In rats treated B. (40 mg/kg), 25% increased [2927 ± 123 perfusion units, (PU)] shams...
B. monnieri extract (BME) is an abundant source of bioactive compounds, including saponins and flavonoids known to produce vasodilation. However, it unclear which components are the more effective vasodilators. The aim this research was investigate vasorelaxant effects mechanisms action on rat isolated mesenteric arteries using organ bath technique. mechanisms, endothelial nitric oxide synthase (eNOS) pathway calcium flux were examined. Saponins (bacoside A bacopaside I), (luteolin apigenin)...
This study explored Bacopa monnieri, a medicinal Ayurvedic herb, as cardioprotectant against ischemia/reperfusion injury using cardiac function and coronary flow end-points. In normal isolated rat hearts, flow, left ventricular developed pressure, heart rate, functional recovery were measured the Langendorff preparation. Hearts perfused with either (i) Krebs-Henseleit (normal) solution, (control), or 30, 100 μg/ml B. monnieri ethanolic extract (30 min), (ii) solution for 10 min preceding...
The leaves of Aquilaria spp. promote "physiological balance", and are "cardiotonic provide blood nourishment". In Asia, these increasingly consumed as tea claimed to benefits cardiovascular function, albeit without any scientific proof. Therefore, this study sought evaluate the action crassna leaf aqueous extract (AE) on vascular function smooth muscle cytotoxicity. AE a main constituent, mangiferin were investigated for their vasorelaxation rat mesenteric arteries aortae in vitro. Acute...
Brahmi essence, developed from Bacopa monnieri (L.) Wettst. standardized extract and mulberry juice, was proven to improve the memory speed of healthy participants aged 55–80 years old, following a 12-week dietary program. However, metabolites have not yet been reported. Our objective characterize altered in plasma, urine, feces volunteers after consumption essence for 12 weeks, using LC-MS metabolomics approach. The were selected OPLS-DA S-plots; 15 7 17 samples tentatively identified by...
Abstract Thai ginseng, Kaempferia parviflora, is widely believed among the Mong hill tribe to reduce perceived effort and improve physical work capacity. parviflora consumed before their daily work. Therefore, we conducted an acute study on effects of K. repeated bouts sprint exercise endurance time exhaustion. Two studies were in college males using a randomized, double-blind, crossover design. Ninety minutes after consumption or starch placebo, participants 1 (n = 19) completed three...
Abstract Bacopa monnier i (L.) Wettst. (Brahmi) is a traditional memory enhancer partly by improved cerebral blood flow. Here we sought to link cognitive function with better flow in randomised double-blinded placebo-controlled trial an elderly cohort. Normotensive Thais, aged 55-80y having mini-mental state examination (MMSE) scores > 25, no dementia or other psycho/neurological disease, normal lipid profile, and biochemistry were recruited. The design was 2 week run-in, 12 intervention...
The COVID-19 pandemic has resulted in severe mental health problems worldwide. Thus, addition to the high number of people who have died from infection with complications, some committed suicide.This study aimed determine relationships between stress, stress-coping behaviors, and suicidal risk among those had become unemployed Thailand due pandemic.This a cross-sectional correlational design included 447 Thais at least 18 years age pandemic. participants were selected through multistage...