Mahmut Tuncay Özgün

ORCID: 0000-0003-4946-2268
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About
Contact & Profiles
Research Areas
  • Prenatal Screening and Diagnostics
  • Ectopic Pregnancy Diagnosis and Management
  • Fetal and Pediatric Neurological Disorders
  • Ovarian function and disorders
  • Gestational Trophoblastic Disease Studies
  • Congenital Anomalies and Fetal Surgery
  • Assisted Reproductive Technology and Twin Pregnancy
  • Maternal and fetal healthcare
  • Reproductive Biology and Fertility
  • Ovarian cancer diagnosis and treatment
  • Pregnancy and preeclampsia studies
  • Endometriosis Research and Treatment
  • Autopsy Techniques and Outcomes
  • Uterine Myomas and Treatments
  • Urological Disorders and Treatments
  • Cleft Lip and Palate Research
  • Reproductive System and Pregnancy
  • Reproductive Health and Contraception
  • Gynecological conditions and treatments
  • Birth, Development, and Health
  • Congenital Heart Disease Studies
  • Neonatal and fetal brain pathology
  • Endometrial and Cervical Cancer Treatments
  • Pediatric Hepatobiliary Diseases and Treatments
  • Maternal and Perinatal Health Interventions

Erciyes University
2014-2024

Saint Barnabas Medical Center
2020

University of Virginia Health System
2020

Beaumont Hospital, Royal Oak
2020

Mount Sinai Medical Center
2020

Kayseri Eğitim ve Araştırma Hastanesi
2015-2016

Bozok Universitesi
2016

Kayser (Italy)
2008-2016

St. Franziskus Hospital
2016

Kocaeli Üniversitesi
2011

Our aim was to investigate the effects of metformin and letrozole on experimentally induced endometriosis in a rat model. Endometriotic implants were surgically formed, 38 rats randomly divided into four groups. Group 1 (control group, 8 rats) given no medication. 2 (metformin 10 100 mg/kg/day oral metformin. 3 200 4 (letrozole 0.1 letrozole. All continued receive treatment for weeks then sacrificed assess size scores adhesions. The histopathologic excised endometriotic foci examined by...

10.1093/humrep/deq016 article EN Human Reproduction 2010-02-03

The aim of this study was to investigate the efficacy, and safety systemic multidose methotrexate (MTX) for treatment cesarean scar pregnancy (CSP).This retrospective cohort performed using records from Department Obstetrics Gynecology, Erciyes University, between 2010 2012. data were analyzed with respect obstetric characteristic, course treatment, clinical, reproductive outcomes.A total 13 patients evaluated. median gestational age at diagnosis 5 weeks days (range: 4-9 weeks). mean beta...

10.1111/jog.12414 article EN Journal of Obstetrics and Gynaecology Research 2014-06-01

Abstract Objective The aim of the study was to compare consistency major/minor fetal anomalies detected by second trimester prenatal ultrasound examination with findings in autopsies following termination pregnancy (TOP) trimester. Design In a 4‐year long prospective study, 107 second‐trimester TOP performed due malformation diagnosed trimester‐ultrasound at tertiary referral center. Ultrasound were compared autopsy findings. Result Of cases major ultrasound, 49% had central nervous system...

10.1002/pd.1710 article EN Prenatal Diagnosis 2007-03-05

The objective of the study was to compare intracytoplasmic sperm injection (ICSI) outcome and gonadotropin doses between obese women with PCOS non-obese patients PCOS. This follow-up represents ICSI outcomes in (BMI ≥ 30 kg/m(2)) compared < kg/m(2)). Obese (n = 18) 26) underwent long protocol pituitary suppression, ovarian stimulation fresh embryo transfer. required higher (2994 IU vs 1719 IU; p 0.001). Miscarriage rate significantly (60% 6.7%, 0.002). Our results are valuable for...

10.3109/01443615.2010.546906 article EN Journal of Obstetrics and Gynaecology 2011-03-18

Recurrent miscarriage is a multifactorial problem associated with genetic abnormalities reflected by inherited disorders. The aim of the present study was to investigate contribution chromosomal and frequency particular type aberration in couples Turkish origin recurrent miscarriages compared patients without miscarriages.A total 336 427 were analyzed.In group, structural abnormality found four (1%). Twelve had mosaic karyotype (3%) rate 4% this group. karyotypes composed polymorphisms 8%...

10.1111/j.1447-0756.2010.01207.x article EN Journal of Obstetrics and Gynaecology Research 2010-06-24

Metformin has been shown to inhibit the growth of endometriotic implants, and reverse endometrial hyperplasia when combined with oral contraceptive in a case report. The aim this study is compare antiproliferative effects medroxyprogesterone acetate (MPA), metformin oopherectomized rat endometrium. Forty Wistar-Albino rats were used, assigned receive saline, 17 β Estradiol hemihydrate (4 mg/kg), mg/kg) (50 MPA (1 mg/day) for 14 days. Histological markers uterotrophy, including height,...

10.3109/09513590.2012.743010 article EN Gynecological Endocrinology 2013-01-10

The aim of this case series was to present the ultrasonographic findings, clinical features, management, and outcome multiple pregnancies with complete hydatidiform mole coexisting fetus (CHMCF).Sonographic features obstetrical perinatal outcomes seven cases CHMCF were analyzed retrospectively.A total included in analysis. Six twins one quadruplet. mean ± SD maternal age 25.3 1.9 years (median: 25; range: 23-29). gestational at diagnosis 16.1 4.6 weeks 17; 11-23). Two achieved by ovulation...

10.1002/jcu.22169 article EN Journal of Clinical Ultrasound 2014-05-28

Objective: The effects of metformin and letrozole on endometrium ovarian reserve were studied in a rat model. Methods: Forty female Wistar albino mature rats at 8 weeks, weighing 180–260 g, used for the study. These randomly divided into four groups. Control group, eight rats, was given no medication by oral gavage. low-dose 10 100 mg/kg/day metformin. high-dose 200 letrozole, 0.1 letrozole. Results: There statistically significant difference endometrial thickness between treatment groups...

10.3109/09513590.2011.589928 article EN Gynecological Endocrinology 2011-07-20

Pentraxin 3 (PTX3) is an acute phase reactant which has been used to detect intra-amniotic infections (IAI) in pregnancy, but the prognostic value of PTX3 concentrations on neonates not studied. We aimed investigate relationship between maternal PTX3-neonatal and early neonatal outcome.The mothers diagnosed with preterm prelabor rupture membranes (PPROM) (n = 28) their infants were included study. studied plasma peripheral blood umbilical/peripheral vein neonates. The mPTX3-nPTX3 outcome...

10.3109/14767058.2014.947574 article EN The Journal of Maternal-Fetal & Neonatal Medicine 2014-07-22

10.1016/j.ejogrb.2006.08.003 article EN European Journal of Obstetrics & Gynecology and Reproductive Biology 2006-09-12

The purpose of this study was to appraise the presence Endometrial Carcinoma (EC) sequence in patients undergoing hysterectomy for Hyperplasia (EH).Eighty-two with indication EH based on endometrial curettage between January 2009 and December 2013 were analyzed respectively All a diagnosis investigated age, parity history diabetes mellitus hypertension. histopathology specimens compared their specimens.A total number 82 women; 48 (58.5%) postmenopausal 34 (41.5%) premenopausal determined...

10.17772/gp/57813 article EN cc-by-nc-nd Ginekologia Polska 2015-01-01

Objective Hirsutism results from hyperandrogenemia and/or exaggerated androgen responsiveness. Among various causes of hirsutism, some patients do not exhibit excess which is called idiopathic hirsutism (IH). The pathogenesis IH could so far be clearly established. Design To investigate the mRNA expression aromatase enzyme and other enzymes having functional roles in steroidogenic pathway, freshly obtained skin tissue subumbilical arm with healthy women. Methods Twenty-one women 15 were...

10.1530/eje-15-0460 article EN European Journal of Endocrinology 2015-07-21

Abstract Objective Clinical features of the distal 10q trisomy syndrome consist mental retardation, facial dysmorphism and renal cardiac anomalies. The presence a sacrococcygeal teratoma (SCT) in fetus with has not been reported yet. Methods A 33‐year‐old, G5, P2 woman singleton pregnancy was referred to our clinic at 24 weeks gestation for further evaluation fetal sacral exophytic mass. Detailed sonographic examination together chromosomal analysis by amniocentesis performed. Results scan...

10.1002/pd.1653 article EN Prenatal Diagnosis 2007-02-13

Abstract Splenogonadal fusion limb defect syndrome (SGFLD) is a very rare abnormality. We report on case with prenatal sonographic findings of fetus postnatally diagnosed SGFLD syndrome. This also the second ultrasonographic diagnosis gastrointestinal malrotation associated SGFLD. A 26‐year‐old primigravid woman was referred to our clinic because nonvisualization both fetal femoral bones at 20 weeks gestation. detailed examination showed complete bilateral absence lower limbs, micrognathia,...

10.1002/jcu.20557 article EN Journal of Clinical Ultrasound 2009-02-27
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