A5101472084- Cardiac Arrhythmias and Treatments
- Nutritional Studies and Diet
- RNA modifications and cancer
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Liver Disease Diagnosis and Treatment
- Cardiac electrophysiology and arrhythmias
- Obesity, Physical Activity, Diet
- Nutrition and Health in Aging
- Atrial Fibrillation Management and Outcomes
- Peptidase Inhibition and Analysis
- Cardiac pacing and defibrillation studies
- Osteoarthritis Treatment and Mechanisms
- Antibiotic Resistance in Bacteria
- Body Composition Measurement Techniques
- Frailty in Older Adults
- Liver Disease and Transplantation
- Chemotherapy-induced cardiotoxicity and mitigation
- Natural product bioactivities and synthesis
- Cardiovascular Disease and Adiposity
- Pancreatic function and diabetes
- Hepatocellular Carcinoma Treatment and Prognosis
- Metabolism, Diabetes, and Cancer
- Diabetes and associated disorders
- Web Data Mining and Analysis
- Gut microbiota and health
Xiangya Hospital Central South University
2021-2025
Central South University
2021-2025
Jiangsu Province Hospital
2021-2025
Nanjing Medical University
2020-2025
Changsha Medical University
2023-2024
Shanghai University of Electric Power
2024
Second Xiangya Hospital of Central South University
2024
Changsha Central Hospital
2023
Peking Union Medical College Hospital
2017-2022
Chinese Academy of Medical Sciences & Peking Union Medical College
2017-2022
Liquid-liquid phase separation (LLPS) is a physiological phenomenon that parallels the mixing of oil and water, giving rise to compartments with diverse physical properties.Biomolecular condensates, arising from LLPS, serve as critical regulators gene expression control, particular significance in context malignant tumors.Recent investigations have unveiled intimate connection between LLPS cancer, nexus profoundly impacts various facets cancer progression, including DNA repair,...
Chlamydia psittaci infection is a zoonotic infectious disease, which mainly inhaled through the lungs when exposed to secretions of poultry that carry pathogenic bacteria. The traditional respiratory specimens or serological antibody testing slow, and false-negative rate high. Metagenomic next-generation sequencing (mNGS) gives promising rapid diagnosis tool.We retrospectively summarized clinical characteristics five C. pneumonia patients diagnosed by mNGS, conducted literature review...
Abstract This study aims to investigate the association between waist circumference and development of hypertension based on a nationwide cohort Chinese population. A total 5330 individuals free at baseline were collected from China Health Retirement Longitudinal Study. The was analyzed by an adjusted cox regression model visualized restricted cubic splines. Further, we applied supervised machine learning methods evaluate importance multiple variates for new‐onset hypertension. Additionally,...
Diabetic cardiomyopathy (DCM) is a pathophysiological condition induced by diabetes mellitus that often causes heart failure (HF). However, their mechanistic relationships remain unclear. This study aimed to identify immune gene signatures and molecular mechanisms of DCM. Microarray data from the Gene Expression Omnibus (GEO) database patients with DCM were subjected weighted co-expression network analysis (WGCNA) modules. Core expression modules intersected database. We analyzed mapped...
Aims: This study aimed to investigate the association between waist circumference and prevalence of (pre) hypertension. Methods: Cross-sectional data from 2007-2018 National Health Nutrition Examination Survey were analyzed. The historical trend abdominal obesity was assessed by Cochran-Armitage test. After preprocessed multiple imputation strategy, we used generalized additive models assess with systolic/diastolic blood pressure performed correlation analysis Spearman coefficient. Moreover,...
, one of the main pathogens that causes community-acquired pneumonia, can lead to
Alanine aminotransferase (ALT), aspartate (AST), and AST to ALT ratio (AAR) were shown be associated with prognosis in some groups of hepatocellular carcinoma (HCC). However, their clinicopathologic prognostic roles HCC patients B-type hepatitis-associated cirrhosis (HBAC) have not been comprehensively investigated. The present study aimed address the issues.A total 125 HBAC after radical hepatectomy included. correlations ALT, AST, AAR parameters, overall/recurrence-free survival,...
Abstract Background The influence of sarcopenic obesity (SO) on overall survival in older adults with hypertension has not been addressed. aim this study was to investigate the prevalence and mortality predictive value various body composition phenotypes, focusing mainly SO, hypertension. Methods We included 1105 hypertensive patients aged ≥ 60 years from National Health Nutrition Examination Survey 1999–2004. Sarcopenia broadly defined based low lean mass (LLM; as measured by dual-energy...
Abstract Aims The prevalence of metabolic syndrome (MetS) is increasing due to ageing populations and lifestyle changes, making it crucial understand the relationship between body fat distribution cardiovascular outcomes. Traditional measures such as mass index (BMI) have limitations in assessing abdominal obesity. roundness (BRI), a novel anthropometric measure combining waist circumference height, has shown promise evaluating this risk. This study aims explore association BRI disease (CVD)...
Objective . The purpose of this study was to investigate the effect kinesio taping on walking ability in patients with foot drop after stroke. Methods Sixty were randomly divided into experimental group (with taping) and control (without taping). 10-Meter Walking Test (10MWT), Timed Up Go (TUGT), stride length, stance phase, swing rotation involved side measured German ZEBRIS gait running platform analysis system used evaluate compare immediate effects taping. All measurements made duplicate...
To probe into the mechanism of Chinese herbs with functions reinforcing kidney and supplementing qi for preventing knee osteoarthritis rabbit.Totally 72 healthy Japan long-ear white rabbits, aged 4 months, were randomly divided 6 groups, blank group (A), model (B), high dose herb (C), middle (D), small (E), aminoglucose hydrochloride capsule control (F), 12 rabbits in each group. All except A, fixed plaster cast six weeks to establish rabbit osteoarthritis. At same time modeling, different...
Carbapenem-resistant organisms (CROs) pose great challenges for clinical treatment. Polymyxin B (PMB) is one of the "last resort" choices CRO infections. We explored possible factors affecting PMB efficacy.This retrospective study involved CRO-infected patients treated with ≥72 h. The endpoint indicator was efficacy. compared characteristics (demographics, pathogenic bacteria, treatment) between who had "clinical success" (CS) and failure" (CF).A total 191 were enrolled: 110 in CS group 81...
Background.Microvascular invasion (MVI) is a significant sign of the invasive property and strong predictor poor prognosis in hepatocellular carcinoma (HCC), life-threatening malignancy.However, recurrenceassociated post-surgical long-term prognosis-associated factors HCC with MVI remain unknown.Objectives.To address abovementioned issues, based on Chinese patient cohort after curative hepatic resection. Material methods.The consisted 62 consecutive patients who underwent resection.The...