A5114339935- Inflammatory Biomarkers in Disease Prognosis
- COVID-19 and healthcare impacts
- Cancer Immunotherapy and Biomarkers
- Renal cell carcinoma treatment
- Neuroendocrine Tumor Research Advances
- Multiple and Secondary Primary Cancers
- Pharmaceutical Practices and Patient Outcomes
- Colorectal and Anal Carcinomas
- Safe Handling of Antineoplastic Drugs
- Pneumocystis jirovecii pneumonia detection and treatment
- Venous Thromboembolism Diagnosis and Management
- Cancer Genomics and Diagnostics
- Palliative Care and End-of-Life Issues
- COVID-19 Clinical Research Studies
- Economic and Financial Impacts of Cancer
- Urologic and reproductive health conditions
- Medication Adherence and Compliance
- Pancreatic and Hepatic Oncology Research
- Ferroptosis and cancer prognosis
- Infection Control and Ventilation
- Global Cancer Incidence and Screening
- Heart Failure Treatment and Management
- COVID-19 and Mental Health
Hacettepe University Hospital
2020-2021
The COVID-19 expected to significantly affect the cancer patients due adverse outcomes with and disruptions in care. Another important point is stress anxiety burden of COVID-19, which could quality life. Patient education vital vulnerability topic disinformation. To determine areas needing improvements patient education, coping stress, problem should be pictured. From this point, we aimed assess perspectives fears about resources knowledge a questionnaire. A total 250 adult applied...
Background We compared the new outpatient clinic referrals during first 10 months of COVID-19 pandemic with year before. Methods baseline characteristics 2208 in 2020 (n=922) and 2019 (n=1286) Χ 2 Mann-Whitney U tests calculated ORs binary logistic regression. To evaluate expected changes cancer survival secondary to stage migration, we used 5-year data Survival, Epidemiology End Results (SEER) Program 2010–2016. The percentage patients inoperable or metastatic disease was significantly...
COVID-19 pandemic could create a collateral damage to cancer care denoting disruptions in due significant burden on healthcare and resource allocations. Herein, we evaluate the early changes inpatient outpatient oncology clinics take snapshot of this at Hacettepe University Cancer Institute.
We aimed to investigate the prognostic value of red cell distribution width (RDW) in metastatic renal carcinoma (mRCC) patients treated with targeted therapy, including sunitinib and pazopanib.A total 104 mRCC were included. The Kaplan-Meier method was used estimate overall survival (OS) progression-free (PFS), long-rank test for comparison. Univariate multivariate Cox proportional hazards models determine association between RDW PFS OS.The OS all cohorts 11.8 mo 25.9 mo, respectively....
Polypharmacy is a common problem in older cancer patients, although the data about polypharmacy and potentially inappropriate prescription practices limited patients treated with immune checkpoint inhibitors (ICIs). Therefore, we aimed to evaluate frequency drug-drug interactions (≥65 years) ICIs.A total of 70 geriatric advanced were included. The was defined as regular use 5 or more drugs. START/STOPP Criteria Version 2 used for medications (PIM) potential omissions (PPO). Medscape Drug...
The albumin-globulin ratio (AGR) could be a prognostic biomarker in patients with cancer, although the data is limited treated immune-checkpoint inhibitors (ICIs).We aimed to evaluate association between AGR and survival ICI-treated patients.The of 212 advanced-stage were retrospectively evaluated this cohort study. overall (OS) progression-free (PFS) multivariate analyses. Additionally, receptor operating curve (ROC) analysis was conducted assess AGR's predictive power very early...
Aim: Blood-based biomarkers like prognostic nutritional index (PNI) are readily available for immunotherapy efficacy, although the data limited. So, we aimed to evaluate association between PNI and overall survival (OS) in immunotherapy-treated patients. Materials & methods: For this retrospective cohort study, of 150 advanced cancer patients were evaluated. The clinical factors OS was evaluated with multivariate Cox-regression analyses. Results: After a median follow-up 8.5 months, 94 died....
OBJECTIVE The albumin to globulin ratio (AGR) has been demonstrated be associated with survival outcomes in various tumor types. However, the prognostic value of AGR patients metastatic renal carcinoma (mRCC) remains unclear. Therefore, this study aimed investigate impact values predicting overall (OS) mRCC treated targeted therapy. MATERIAL AND METHODS A total 163 therapy between 2008 and 2019 were enrolled. was measured as AGR: albumin/(total protein-albumin). Kaplan-Meier method long-rank...