A5079392226- Vaccine Coverage and Hesitancy
- Pneumonia and Respiratory Infections
- Cardiac Arrest and Resuscitation
- Anesthesia and Neurotoxicity Research
- COVID-19 Impact on Reproduction
- SARS-CoV-2 and COVID-19 Research
- Cardiac Ischemia and Reperfusion
- Congenital Diaphragmatic Hernia Studies
- Bacterial Infections and Vaccines
- Antibiotics Pharmacokinetics and Efficacy
- Respiratory and Cough-Related Research
- Pneumocystis jirovecii pneumonia detection and treatment
- Clostridium difficile and Clostridium perfringens research
- Traumatic Brain Injury and Neurovascular Disturbances
- Diversity and Career in Medicine
- Neonatal Respiratory Health Research
- Emergency and Acute Care Studies
- Non-Invasive Vital Sign Monitoring
- Global Health Workforce Issues
- Healthcare professionals’ stress and burnout
University of Pittsburgh
2015-2024
Children's Hospital of Pittsburgh
2021-2023
Remote Ischemic Conditioning (RIC), induced by brief cycles of ischemia and reperfusion, protects vital organs from a prolonged ischemic insult. While several biochemical mediators have been implicated in RIC's mechanism action, it remains unclear whether the localization or "dose" RIC affects extent protective signaling. In this randomized crossover study healthy individuals, we tested number its (arm versus thigh) determines signaling cytoprotection. Subjects received either arm thigh then...
Residents and fellows with children face distinct challenges; however, knowledge of factors associated increased parental stress is limited.This study aimed to investigate experiences concerns physician trainees identify higher stress.An anonymous survey was distributed all resident fellow in June 2021 assess regarding leave, breastfeeding, childcare. We used the Parental Stress Scale (PSS) analyzed results using descriptive statistics, linear regression, thematic analysis.Of 1719 trainees,...
Background The evaluation of febrile infants ≤60 days age is often guided by established protocols. However, structural racism and physicians’ implicit bias may affect how such clinical guidelines are applied. Objective To determine the association between self-identified race, insurance type, ZIP code–based median household income (MHI) receiving a guideline-concordant lumbar puncture (GCLP) in infants. Methods This was 3-year retrospective cross-sectional study all old presenting to...
Initial oral antibiotics may be as effective intravenous (IV) for children hospitalized with community-acquired pneumonia (CAP), but further data are needed.
Abstract Corresponding Author: Jillian M. Cotter, MD, MSCS; Assistant Professor, Department of Pediatrics, Section Hospital Medicine; Children’s Colorado and University School 13123 E 16th Ave, Box B302, Aurora, CO 80045; jillian.cotter@childrenscolorado.org; 720-777-5241 Alternate Lilliam Ambroggio, PhD, Associate Emergency Medicine lilliam.ambroggio@childrenscolorado.org; Conflicts interest/disclosures: Drs. Cotter Ambroggio receive grant support from Pfizer Inc for a study unrelated to...
Introduction: RIC is protective against heart and brain ischemia. The mechanisms are still debated as dose effects of repetitive cycles using the upper or lower extremity. Increases in reactive hyperemia (RH), plasma nitrite oxygen species (ROS) may underlie signaling. Hypothesis: Repetitive will be more effective thigh than forearm increasing inhibiting mitochondrial function with small increases ROS. Methods: Ten healthy individuals were subjected to 4 5 min limb ischemia, delivered by...
Background: Endothelial dysfunction (ED) may occur after cardiac arrest (CA) both due to the underlying patient comorbidities which result in CA and global ischemia-reperfusion results. The prevalence of ED is poorly characterized as any association with outcomes. Hypothesis: will be more common asphyxial arrests, prolonged CPR times subjects multiple coronary artery risk factors. associate worsened Methods: Prospective, observational study 23 return spontaneous circulation (ROSC) expected...