A5051256277- Transcranial Magnetic Stimulation Studies
- Extracellular vesicles in disease
- Motor Control and Adaptation
- Cellular transport and secretion
- Vascular Anomalies and Treatments
- Facial Nerve Paralysis Treatment and Research
- Dysphagia Assessment and Management
- Muscle activation and electromyography studies
- Media Influence and Health
- Hearing, Cochlea, Tinnitus, Genetics
- Marine animal studies overview
- Nutrition and Health in Aging
- Smoking Behavior and Cessation
- Crime, Deviance, and Social Control
- Political and Social Issues
- EEG and Brain-Computer Interfaces
- Head and Neck Cancer Studies
- Lipid Membrane Structure and Behavior
- Antiplatelet Therapy and Cardiovascular Diseases
- Colorectal and Anal Carcinomas
- Cancer Treatment and Pharmacology
- Connexins and lens biology
- Intracranial Aneurysms: Treatment and Complications
- Gastric Cancer Management and Outcomes
- Trigeminal Neuralgia and Treatments
Memorial Sloan Kettering Cancer Center
2025
Stanford University
2024
University of Colorado Anschutz Medical Campus
2022-2024
Oregon Health & Science University
2020-2022
University of Oregon
2015
Detection of sound and head movement requires mechanoelectrical transduction (MET) channels at tips hair-cell stereocilia. In vertebrates, the transmembrane channel-like (TMC) proteins TMC1 TMC2 fulfill critical roles in MET, substantial evidence implicates these TMCs as subunits MET channel. To identify developmental functional this Tmc subfamily zebrafish inner ear, we tested effects truncating mutations tmc1 , tmc2a tmc2b on vivo mechanosensation onset hearing balance, before gender...
136 Background: National guidelines recommend surgery when pathology analysis of a colorectal polyp reveals high-risk features: positive margin/piecemeal resection (PM/PR), lymphovascular/perineural invasion (LVI/PNI), poor differentiation (PD), or tumor budding (TB). However, some patients choose to avoid surgery, with its morbidity and quality-of-life implications, despite the risk residual disease. Methods: This single-center cohort study determined rates luminal lymph node disease...
Mutations in human VPS4A are associated with neurodevelopmental defects, including motor delays and defective muscle tone. encodes a AAA-ATPase that is required for membrane scission, but how mutations lead to impaired control of function not known. Here we identified mutation zebrafish vps4a , T248I, affects sensorimotor transformation. In biochemical experiments show the T248I reduces ATPase activity Vps4a disassembly its substrate, ESCRT filaments, which mediate scission. Consistent...
Mutations in human
The purpose of this study was to assess the effect a cognitive task on motor cortex excitability and inhibition. Transcranial magnetic stimulation performed 20 healthy individuals (18-24 years; 9 females) measure evoked potentials (MEPs) cortical silent periods at baseline, during, following secondary task. MEP amplitude increased from 0.50 ± 0.09-0.87 mV during (p = .04), returned baseline (0.48 0.31 mV; p .90) posttask. CSP duration also 93.48 28.76-113.6 33.68 ms .001) task, posttask...
Objectives/Hypothesis From the 1970s–1990s U.S. Smokeless Tobacco Company (USST) conducted aggressive campaigns to solicit college students buy their smokeless tobacco (ST) products. The scope, scale, methods, and impact of this youth marketing campaign have yet be analyzed in academic literature. Study Design Historical research study. Methods Internal industry documents describing USST were obtained via University California, San Francisco's repository company records. Marketing materials...
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It is well understood that the addition of a secondary cognitively demanding task to an ongoing motor results in decrement function. However, effect such cognitive on cortex function not understood. PURPOSE: To assess excitability and inhibition. METHODS: Transcranial magnetic stimulation was performed 20 healthy individuals (18-24 years; 9 females) measure evoked potentials (MEPs) cortical silent periods (CSPs) first dorsal interosseous at baseline, during, following task. RESULTS: The MEP...