Servet Kavak

ORCID: 0000-0003-4983-6071
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About
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Research Areas
  • Adipose Tissue and Metabolism
  • Nitric Oxide and Endothelin Effects
  • Trace Elements in Health
  • Metabolism, Diabetes, and Cancer
  • Heavy Metal Exposure and Toxicity
  • Spaceflight effects on biology
  • Peroxisome Proliferator-Activated Receptors
  • Selenium in Biological Systems
  • Kidney Stones and Urolithiasis Treatments
  • Salivary Gland Disorders and Functions
  • Adipokines, Inflammation, and Metabolic Diseases
  • Sulfur Compounds in Biology
  • Ion channel regulation and function
  • Nigella sativa pharmacological applications
  • Vitamin C and Antioxidants Research
  • Muscle activation and electromyography studies
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Chemotherapy-induced organ toxicity mitigation
  • Eicosanoids and Hypertension Pharmacology
  • Bone Metabolism and Diseases
  • Bone health and osteoporosis research
  • Dermatologic Treatments and Research
  • Apelin-related biomedical research
  • Vitamin D Research Studies
  • Cardiovascular Function and Risk Factors

Izmir University
2022-2025

Sağlık Bilimleri Üniversitesi
2025

Bakırçay Üniversitesi
2022-2023

Muğla University
2015-2017

Institute of Biophysics
2013

Van Yüzüncü Yıl Üniversitesi
2010-2012

Cukurova University
2006-2009

Objectives We aimed to investigate the value of leukocyte biomarkers and disease scores for early detection infection in patients who have undergone elective colorectal surgery malignancy. Methods conducted a prospective study at training research hospital. Patients developed were considered be an Infection group, others regarded as Control group. For individuals both groups, Sequential Organ Failure Assessment Score (SOFA), quick SOFA, National Early Warning (NEWS) calculated blood samples...

10.1177/03000605251315920 article EN cc-by-nc Journal of International Medical Research 2025-02-01

We aimed to investigate the effects of thymoquinone (TQ) against Doxorubicin (DOX)-induced toxicity in liver, lung, kidney, testes, diaphragm and stomach tissues rats.Healthy twenty-eight Wistar albino male rats aged three months, were divided into four groups, each containing seven animals: Group 1: Control (C group); injected intraperitoneally with saline 5 times every other day given by gavage vehicle solution 2 (T group): Rats treated (10mg/kg gavage), 3 (D doxorubicin (3mg/kg) 4 (DT...

10.29261/pakvetj/2023.070 article EN cc-by-nc Pakistan Veterinary Journal 2023-01-01

The aim of this study is to evaluate the influences short-term treatment with levosimendan (chemical formula: C 14 H 12 N 6 O) on oxidative stress and some trace element levels in renal tissues healthy rats. A total 20 male Wistar-albino rats were randomly divided into two groups, each consisting 10 Animals first group not treated served as control. second injected intraperitoneally µg/kg group. both groups killed 3 days after treatment, their kidneys harvested for determination tissue...

10.1177/0748233712451773 article EN Toxicology and Industrial Health 2012-06-21

Abstract We investigated the effect of rosiglitazone (RSG), a high‐affinity ligand for peroxisome proliferator‐activated receptor gamma which mediates insulin‐sensitizing actions, on lipid profile and oxidative status in streptozotocin (STZ)‐induced Type 2 diabetes mellitus (DM) rats. Wistar albino male rats were randomly divided into an untreated control group (C), C + RSG was treated with (4 mg kg −1 ) two times day by gavage, diabetic (D) that single intraperitoneal injection STZ (45 mgkg...

10.1002/cbf.1469 article EN Cell Biochemistry and Function 2008-03-17

This experiment was designed to investigate the effect of levosimendan injection on lipid peroxidation product malondialdehyde (MDA) and antioxidant glutathione (GSH) levels, activities enzymes in myocardium rats. Twenty male Wistar-albino rats were divided randomly into 2 study groups, each consisting 10 The animals first group not treated with drug served as control. It found that MDA GSH levels decreased injected group. Superoxide dismutase, peroxidase, catalase carbonic anhydrase enzyme...

10.1177/0748233712436643 article EN Toxicology and Industrial Health 2012-02-23

With the developments in wireless technologies, living beings are increasingly exposed to electromagnetic fields (EMFs). EMFs known affect bone metabolism and muscle tissue. However, their effects on bones skeletal muscles controversial, as some studies have reported positive while others adverse effects. In this study, of radiofrequency radiation (RFR) biomechanics tissues were investigated diabetic healthy rats. Rats 3.5 GHz RFR for 2 h per day 30 days. Bone measurements taken evaluate...

10.1080/13102818.2023.2199096 article EN cc-by Biotechnology & Biotechnological Equipment 2023-03-10

The objective of this study was to evaluate the effect short-term levosimendan exposure on oxidant/antioxidant status and trace element levels in testes rats under physiological conditions. Twenty male Wistar albino were randomly divided into two groups 10 animals each. Group 1 not exposed served as control. Levosimendan (12 µg/kg) diluted mL 0.9% NaCl administered intraperitoneally group 2. Animals both sacrificed after 3 days their harvested for determination changes tissue levels. Tissue...

10.1590/s0100-879x2012007500075 article EN cc-by Brazilian Journal of Medical and Biological Research 2012-08-01

The goal of this study was to biomechanically and morphologically research both the impact mobile phone like radiofrequency radiations (RFR) on tibia effects skeletal muscle through oxidative stress parameters. Fifty-six rats (200-250 g) were put into groups: healthy sham (n = 7), RFR (900, 1800, 2100 MHz) 21), diabetic 7) 21). Over a month, each group spent two hours/day in Plexiglas carousel. experimental exposed RFR, but groups not. At end experiment, right bones tissue removed....

10.1080/15368378.2023.2179065 article EN Electromagnetic Biology and Medicine 2023-01-02

This study was designed to investigate whether extracorporeal shock wave lithotripsy (ESWL) exposure parotid gland produces an oxidative stress in glands of rats. Twelve male Wistar-albino rats, 6 months age with average body weight 250–300 g, were divided randomly into two groups, each consisting six The animals the first group did not receive any treatment and served as control. left 2 (ESWL treated) received a thousand 18 kV waves after anesthetizing rats 50 mg/kg ketamine. both groups...

10.1177/0748233712457452 article EN Toxicology and Industrial Health 2012-08-29

Purpose . In this study, we tested the hypothesis that rosiglitazone (RSG) with insulin is able to quench oxidative stress initiated by high glucose through prevention of NAD(P)H oxidase activation. Methods and Materials Male albino Wistar rats were randomly divided into an untreated control group (C), a diabetic (D) was treated single intraperitoneal injection streptozotocin (45 mgkg −1 ), RSG twice daily gavage once subcutaneous (group B). HbA1c blood levels in circulation malondialdehyde...

10.1155/2012/905683 article EN cc-by Experimental Diabetes Research 2012-01-01

To evaluate the characteristic features of mechanical responses and membrane potential changes induced by repetitive pulsed electromagnetic field (PEMF, 50 Hz, 5 mT) in thoracic aorta rings obtained from streptozotocin-induced diabetic healthy control rats to determine if PEMF could ameliorate problems associated with diabetes.Sixty male Wistar weighing 250-290 g were randomly divided into two experimental groups, each containing 30 animals. Streptozotocin was given via tail vein produce...

10.1080/09553000903009522 article EN International Journal of Radiation Biology 2009-01-01

Abstract Introduction: In this study we investigated the effect of crush and axotomy phrenic nerves on oxidative stress antioxidant enzyme activities in rat diaphragm muscle. Methods: The animals first group were not crushed or axotomized served as controls. Phrenic rats second third groups Results: malondialdehyde level increased muscles after both axotomy. enzymes, such superoxide dismutase, glutathione peroxidase, carbonic anhydrase, catalase, decreased Conclusions: Crushing axotomizing...

10.1002/mus.22312 article EN Muscle & Nerve 2011-10-03

This study was designed to investigate whether exposure short-term extracorporeal shock wave lithotripsy (ESWL) produces histologic changes or induces apoptosis in the kidney, adrenal glands diaphragm muscle rats. The effect of waves on kidney male Wistar rats ( n = 12) investigated an experimental setting using a special ESWL device. Animals were killed at 72 h after last ESWL, and tissues stained with situ Cell Death Detection Kit, Fluorescein. Microscopic examination performed by...

10.1177/0748233712462481 article EN Toxicology and Industrial Health 2012-10-24

This study was designed to investigate whether the short-term extracorporeal shockwave lithotripsy (ESWL) exposure kidney produces an oxidative stress and a change in some trace element levels liver diaphragm muscles of rats. Twelve male Wistar albino rats were divided randomly into two groups, each consisting six The animals first group did not receive any treatment served as control group. right-side kidneys 2 treated with two-thousand 18 kV shock waves while anesthetized 50 mg kg(-1)...

10.1002/cbf.2802 article EN Cell Biochemistry and Function 2012-01-16
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