A5011892406- Bladder and Urothelial Cancer Treatments
- Epigenetics and DNA Methylation
- Ferroptosis and cancer prognosis
- Sexual function and dysfunction studies
- Renal cell carcinoma treatment
- MicroRNA in disease regulation
- Dialysis and Renal Disease Management
- Chronic Kidney Disease and Diabetes
- Urinary Bladder and Prostate Research
- Obstructive Sleep Apnea Research
- Renal and related cancers
- Birth, Development, and Health
- Esophageal Cancer Research and Treatment
- Cancer Immunotherapy and Biomarkers
Chengdu Third People's Hospital
2023-2025
Southwest Jiaotong University
2023
Sichuan University
2021-2022
West China Hospital of Sichuan University
2021-2022
Chronic kidney disease (CKD) is a serious complication of diabetes, and the global burden gradually increasing. This study systematically analyzed trends future projections worldwide chronic caused by type 1 2 diabetes mellitus based on Global Burden Disease Study (GBD) using data from 1990 to 2021. Number deaths, Age-standardized mortality rates, disability-adjusted life years (DALYs), age-standardized DALYs rate were used estimate burden. The Estimated Annual Percentage Changes (EAPCs)...
Cancer-associated fibroblasts (CAFs) are the most important cellular components in bladder urothelial carcinoma (BLCA) and involved development immunosuppression of BLCA. Therefore, we aimed to construct a CAF-associated signature for predicting prognosis immunotherapy response patients with BLCA.CAF infiltration stromal score were quantified using two algorithms. Weighted gene co-expression network analysis (WGCNA) was performed identify modules hub genes. Univariate Cox Least Absolute...
Background: The unfolded protein response (UPR) plays a significant role in maintaining hemostasis tumor cells, which are crucial for growth, invasion, and resistance to therapy. This study aimed develop UPR-related signature explore its correlation with immunotherapy chemotherapy bladder cancer. Methods: differentially expressed genes were put into Lasso regression screen out prognostic genes, constituted the UPR signature, incorporated multivariate Cox generate risk scores. Subsequently,...