A5078566370- Electromagnetic Fields and Biological Effects
- Spaceflight effects on biology
- Quantum Chromodynamics and Particle Interactions
- Particle physics theoretical and experimental studies
- Magnetic and Electromagnetic Effects
- High-Energy Particle Collisions Research
- Planarian Biology and Electrostimulation
- Wound Healing and Treatments
- Tendon Structure and Treatment
- Tissue Engineering and Regenerative Medicine
- Genetic and Kidney Cyst Diseases
- Biofield Effects and Biophysics
- Alkaline Phosphatase Research Studies
- Bone health and osteoporosis research
- S100 Proteins and Annexins
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
Sachtleben (Germany)
2015-2023
Universität Hamburg
2019-2023
University Medical Center Hamburg-Eppendorf
2019-2023
University of Bonn
2011-2013
For many years electromagnetic fields (EMFs) have been used clinically with various settings as an exogenous stimulation method to promote fracture healing. However, underlying mechanisms of action and EMF parameters responsible for certain effects remain unclear. Our aim was investigate the influence defined EMFs on human osteoblasts' osteoclasts' viability function. Primary osteoblasts osteoclasts were treated 3 times weekly 21 days during their maturation process using Somagen® device...
Exposure to extremely low frequency pulsed electromagnetic fields (ELF-PEMF) is supposed simulate local EMF generated during mechanical stimulation of bone and may therefore be used improve regeneration. This study aimed at optimizing the exposure strategy investigating underlying mechanisms a 16 Hz ELF-PEMF, previously reported boost osteoblast function. Comparing influences daily continuous (30 min every 24 h) intermittent (10 8 ELF-PEMF on osteoprogenitor cells revealed that enhanced...
Delayed fracture healing and non-unions impose an enormous burden on individuals society. Successful requires tight communication between immune cells bone cells. Macrophages can be found in all phases. Due to their high plasticity long life span, they represent good target for modulation. In the past, extremely low frequency pulsed electromagnet fields (ELF-PEMFs) have been shown exert cell-specific effects depending field conditions. Thus, aim was identify specific ELF-PEMFs able modulate...
Cigarette smoking (CS) is one of the main factors related to avoidable diseases and death across world. smoke consists numerous toxic compounds that contribute development osteoporosis fracture nonunion. Exposure pulsed electromagnetic fields (PEMF) was proven be a safe effective therapy support bone healing. The aims this study were investigate if extremely low frequency (ELF-) PEMFs may beneficial treat CS-related disease, which effect duration exposure has. In study, immortalized human...
Fracture-healing is a highly complex and timely orchestrated process. Non-healing fractures are still major clinical problem treatment remains difficult. A 16 Hz extremely low-frequency pulsed electromagnetic field (ELF-PEMF) was identified as non-invasive adjunct therapy supporting bone-healing by inducing reactive oxygen species (ROS) Ca
The effects of extremely low-frequency electromagnetic field (ELF-MF) exposure on living systems have been widely studied at the fundamental level and also claimed as beneficial for treatment diseases over 50 years. However, underlying mechanisms cellular targets ELF-MF remain poorly understood has plagued with controversy stemming from an endemic lack reproducibility published findings. To address this problem, we here demonstrate a technically simple reproducible EMF protocol to achieve...