A5001096106- Gut microbiota and health
- Dialysis and Renal Disease Management
- Tryptophan and brain disorders
- Genetics, Aging, and Longevity in Model Organisms
- PARP inhibition in cancer therapy
Pusan National University
2022
Epidemiological and experimental evidence has implicated a potent link between antibiotic exposure susceptibility to various diseases. Clinically, treatment during platinum chemotherapy is associated with poor prognosis in patients malignancy. In the present study, mucosal was assessed for its impact on renal distress as sequela of platinum-based chemotherapy. Clinical transcriptome dataset-based evaluations demonstrated that levels dysbiosis-responsive genes were elevated distress,...
Upon exposure to internal or environmental insults, ribosomes stand sentinel. In particular, stress-driven dysregulation of ribosomal homeostasis is a potent trigger adverse outcomes in mammalians. The present study assessed whether the insult affects aging process via regulation sentinel organs such as gut. Analyses human dataset demonstrated that elevated features stress are inversely linked barrier maintenance biomarkers during process. Ribosome-insulted worms displayed reduced lifespan,...