A5103130881- Blood Coagulation and Thrombosis Mechanisms
- Radiomics and Machine Learning in Medical Imaging
- Dialysis and Renal Disease Management
- Transcranial Magnetic Stimulation Studies
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Brain Tumor Detection and Classification
- Vitamin K Research Studies
- Adipokines, Inflammation, and Metabolic Diseases
- Heparin-Induced Thrombocytopenia and Thrombosis
- Atrial Fibrillation Management and Outcomes
- Radiology practices and education
- Fatty Acid Research and Health
- Indigenous Studies and Ecology
- Bone health and osteoporosis research
- Chronic Kidney Disease and Diabetes
- Genetic and Kidney Cyst Diseases
- Flood Risk Assessment and Management
- Neurological Complications and Syndromes
- Antioxidant Activity and Oxidative Stress
- Antiplatelet Therapy and Cardiovascular Diseases
- Blood donation and transfusion practices
- Protein Kinase Regulation and GTPase Signaling
- Delphi Technique in Research
- Muscle activation and electromyography studies
- Glioma Diagnosis and Treatment
Copenhagen University Hospital
2022-2025
University of Copenhagen
2022-2025
Rigshospitalet
2022-2025
Danish Maritime Authority
2017
Aalborg University Hospital
1982-1990
National Institute of Oncology
1982
Aalborg University
1980
Objective: Reliable reading and annotation of chest X-ray (CXR) images are essential for both clinical decision-making AI model development. While most the literature emphasizes pulmonary findings, this study evaluates consistency reliability annotations extrapulmonary using a labelling scheme. Methods: Six clinicians with varying experience levels (novice, intermediate, experienced) annotated 100 CXR diagnostic scheme, in two rounds, separated by three-week washout period. Annotation was...
A family with a tendency to thrombosis and decreased antithrombin III (AT III) activity in plasma, but normal immunoreactive AT is reported. 7 members of the had defect, 4 whom have thrombotic episodes. The importance biological determination when studying patients recurrent episodes emphasized.
In the context of brain tumour response assessment, deep learning-based three-dimensional (3D) segmentation has shown potential to enter routine radiological workflow. The purpose present study was perform an external evaluation a state-of-the-art learning 3D algorithm (HD-GLIO) on independent cohort consecutive, post-operative patients. For 66 consecutive magnetic resonance imaging examinations, we compared delineations contrast-enhancing (CE) lesions and non-enhancing T2/FLAIR hyperintense...
Insulin-dependent diabetes mellitus (IDDM) is associated with an increased risk of coronary artery disease (CAD). There some evidence that polyunsaturated fatty acids the marine n-3 type (n-3 PUFA's) may offer protection against CAD. We have studied effect short-term dietary supplementation PUFAs on lipids, haemostasis, neutrophil and monocyte chemotaxis in 10 patients IDDM. The were given 4 g daily (fish oil) for 6 weeks investigated before after supplement. No significant effects platelets...
Consistent annotation of data is a prerequisite for the successful training and testing artificial intelligence-based decision support systems in radiology. This can be obtained by standardizing terminology when annotating diagnostic images. The purpose this study was to evaluate consistency among radiologists using novel labeling scheme chest X-rays. Six with experience ranging from one sixteen years, annotated set 100 fully anonymized blinded on two separate occasions. Statistical analyses...
Renal tubular sodium and water handling determined by the lithium clearance technique, plasma concentrations of atrial natriuretic peptide (ANP), angiotensin II, aldosterone, arginine vasopressin (AVP), urinary excretion prostaglandin E2 (PGE2) were both during basal conditions before after intravenous loading with a 2.5% chloride solution in patients polycystic kidney disease (PKD), ten normal or slightly reduced function (PKDN) seven moderately (PKDR), 15 healthy controls. In PKDN was...
Protein C activity was studied in 14 hemodialysis patients and compared with healthy, age- sex-matched controls. Prior to dialysis, protein depressed all (mean 0.43, range 0.24–0.68 versus mean 1.00, 0.79–1.14). During rose but did not reach normal levels. The reduced may play an important role the altered hemostatic equilibrium chronic hemodialysis.
Abstract Sørensen PJ. Nielsen AH. Knudsen F. Schmitz O. Dyerberg J (Department of Nephrology. and Department Clinical Chemistry. Aalborg Hospital. Aalborg. University Hospital Århus. Denmark). Protein C in renal allotransplantation during the perioperative period. activity, both coagulant amidolytic, as well antigen level were studied period 40 transplants recipients 21 healthy controls. At transplantations protein activity was significantly lower patients than normal controls, further...
The Brain Tumor Segmentation (BraTS) Challenge has been a main driver of the development deep learning (DL) algorithms and provides by far largest publicly available expert-annotated brain tumour dataset but contains solely preoperative examinations. aim our study was to facilitate use BraTS for training DL segmentation postoperative setting. To this end, we introduced an automatic conversion three-label annotation protocol two-label suitable segmentation. assess viability label conversion,...
Protein C activity was determined in patients with terminal renal failure treated three different ways: hemodialysis (n = 20), hemofiltration 7) and continuous ambulatory peritoneal dialysis 7). The protein decreased uremia, independent of the kidney replacement therapy employed, compared 21 normal controls. In increased significantly during a treatment, whereas treatment normalized depressed activity. vitro experiments inhibition plasma ultrafiltrates could not reveal presence an inhibitor...
AbstractThe effect on plasma antithrombin III (AT III) and protein C a supplement with polyunsaturated fatty acids (PUFA's) was investigated in double-blind study 36 patients stable angina pectoris. All participants were given to their normal diets of vegetable oil (4.8 g n-6 PUFA's) for 4 weeks then randomized the same or fish n-3 12 weeks. Both supplements resulted statistically significant decrease AT activity, but there no differences between two different types PUFA's. Antithrombin...