A5086009071- Memory and Neural Mechanisms
- Neurobiology and Insect Physiology Research
- Neural dynamics and brain function
- Photoreceptor and optogenetics research
- Neural and Behavioral Psychology Studies
- Circadian rhythm and melatonin
- Genetics, Aging, and Longevity in Model Organisms
- Aquaculture Nutrition and Growth
- Neural Networks and Applications
- Insect and Arachnid Ecology and Behavior
- Consumer Market Behavior and Pricing
- Transportation and Mobility Innovations
- Invertebrate Immune Response Mechanisms
- Digital Platforms and Economics
- Physiological and biochemical adaptations
The University of Tokyo
2017-2024
Memory includes the processes of acquisition, consolidation and retrieval. In study aversive olfactory memory in Drosophila melanogaster, flies are first exposed to an odor (conditioned stimulus, CS+) that is associated with electric shock (unconditioned US), then another (CS-) without US, before allowing choose avoid one two odors. The center for formation mushroom body which consists Kenyon cells (KCs), dopaminergic neurons (DANs) output (MBONs). However, roles individual not fully...
Abstract Adaptive behavior requires integrating prior knowledge of action outcomes and sensory evidence for making decisions while maintaining future actions. As outcome- sensory-based are often tested separately, it is unclear how these processes integrated in the brain. In a tone frequency discrimination task with two sound durations asymmetric reward blocks, we found that neurons medial prefrontal cortex male mice represented additive combination expectations choices. The inputs choices...
The nematode Caenorhabditis elegans memorizes various external chemicals, such as ions and odorants, during feeding. Here we find that C. is attracted to the monosaccharides glucose fructose after exposure these in presence of food; however, it avoids them without conditioning. attraction requires a gustatory neuron called ASEL. ASEL activity increases when concentration decreases. Optogenetic stimulation promotes forward movements; conditioning, turning, suggesting behavioral output...
Abstract Adaptive behavior requires integrating prior knowledge of action outcomes and sensory evidence for making decisions while maintaining future actions. As outcome- sensory-based are often tested separately, it is unclear how these processes integrated in the brain. In a tone frequency discrimination task with two sound durations asymmetric reward blocks, we found that neurons medial prefrontal cortex male mice represented additive combination expectations choices. The inputs choices...
Abstract In the olfactory aversive conditioning of Drosophila melanogaster, an odor, conditioned stimulus (CS), is associated with electric shock, unconditioned (US). The Rutabaga adenylyl cyclase in Kenyon cells (KCs) fly brain synthesizes cAMP, which believed to serve as coincidence detector synergistically stimulated by calcium/calmodulin evoked odor reception and GαS released response dopamine signaling elicited shock. However, live imaging analyses revealed that stimulation itself...
A major function of the brain is to make decisions by moving physical body according sensory inputs. Previous studies have described development artificial neural networks (ANNs) model decision-making circuits and compared activity units with that real neurons in animals. Here, we developed a real-cyber hybrid network (HNN) directly uses as inputs an ANN predict movements head-fixed mice during task. Using spike from cortical or subcortical regions, especially parietal cortex, HNN predicted...
Abstract The nematode Caenorhabditis elegans memorizes various external chemicals, such as ions and odorants, during feeding. Here we find that C. is attracted to the monosaccharides glucose fructose after exposure these in presence of food; however, it avoids them without conditioning. attraction requires a left-sided ASE gustatory neuron called ASEL. ASEL activity increases when concentration decreases. Optogenetic stimulation promotes forward movements; conditioning, turning, suggesting...
Market cannibalization is inevitable when there are two or more competing marketing approaches to the same customer base. The problem has been discussed in context of search advertising individual advertisers, whereas this paper we discuss that platform companies face dealing with multiple advertisers. In online advertising, they must properly serve ads varying mass appeal users various interests. For them, it important maximize value for advertisers and also platform. To do so, deploy user...