- Statistical Methods in Clinical Trials
- Health Systems, Economic Evaluations, Quality of Life
- Disability Rights and Representation
- Psoriasis: Treatment and Pathogenesis
- Land Use and Ecosystem Services
- Ethics in Business and Education
- Innovations in Educational Methods
- Facial Rejuvenation and Surgery Techniques
- Religion, Society, and Development
- Gender and Technology in Education
- Pancreatitis Pathology and Treatment
- Geographies of human-animal interactions
- Cultural Heritage Materials Analysis
- Politics and Conflicts in Afghanistan, Pakistan, and Middle East
- Urban Planning and Landscape Design
- Pragmatism in Philosophy and Education
- Optimal Experimental Design Methods
- Electrolyte and hormonal disorders
- Terrorism, Counterterrorism, and Political Violence
- Education Systems and Policy
- Inclusion and Disability in Education and Sport
- Higher Education Learning Practices
- Education, Achievement, and Giftedness
- Identification and Quantification in Food
- Blood Pressure and Hypertension Studies
Pfizer (United States)
2024-2025
Shandong University of Political Science and Law
2024
University of Strathclyde
2023
Beijing University of Technology
2023
Iowa State University
2022
Zhejiang University of Science and Technology
2021
University of Wollongong
2021
John H. Stroger, Jr. Hospital of Cook County
2018
Education Scotland
2016-2017
Abstract Ritlecitinib is an orally bioavailable, small molecule that has been approved by the U.S. Food and Drug Administration (FDA) as a once‐daily oral treatment option for people 12 years of age older with severe alopecia areata. This article assessed exposure–response (ER) relationship eyebrow eyelash assessment (EBA/ELA) scores on ritlecitinib compared them to Severity Alopecia Tool (SALT) score (primary endpoint) ER ritlecitinib. EBA ELA both are numeric rating scales (NRS) four...
Objectives: In pediatric population PK (PopPK) model development, sparse data and limited covariate information can prevent accurate estimation for parameters their variability. We explored three methods to utilize prior PopPK development. The objectives are summarize the performance from each method highlight key differences advantages associated with these methods. Methods: A was previously established Drug using samples of adults adolescents two Phase 1, one 2b/3, 3 studies. described...
Abstract The recruitment of a parallel, healthy participants (HPs) arm in renal and hepatic impairment (RI HI) studies is common strategy to assess differences pharmacokinetics. Limitations this approach include the underpowered estimate exposure use drug population for which there no benefit. Recently, method was published by Purohit et. al. (2023) that leveraged prior pharmacokinetic (PopPK) modeling-based simulation infer distribution ratios between RI/HI arms HPs. successful, but it...
The implementation of lecture recording (LR) technology is becoming common practice in higher education (HE). While it often promoted as a technological solution to inclusion, there need for more in-depth research examine such assumptions. This study was conducted research-intensive elite university the UK, employing semi-structured interviews with 15 students and 10 teaching staff focusing on students' voices an under-represented dimension LR research. student participants recognised...
Abstract PoissonERM is an R package used to conduct exposure–response (ER) analysis on binary outcomes for establishing the relationship between exposure and occurrence of adverse events (AE). While Poisson regression could be implemented with glm(), provides a simple way semi‐automate entire generate abbreviated report as markdown (Rmd) file that includes essential details brief conclusions. processes provided data set using information from user's control script generates summary...
Fully Bayesian approaches are not commonly implemented for population pharmacokinetic (PK) modeling. In this paper, we evaluate the use of Stan with R and Torsten PK modeling somatrogon, a recombinant long-acting growth hormone approved treatment deficiency. As software inference, provides an easy way to conduct MCMC sampling wide range models efficient algorithms, there several diagnostic tools convergence other potential issues. Three different sets priors were evaluated estimation...
Peer learning indicates an educational environment where students teach and learn from each other. Understanding how students' peer behaviors change over time would bring benefits such as providing clues to teachers encourage learning. Studying behavior dynamics in realistic environments could be time-consuming due the cost of human labor. This paper proposes use computer simulations efficient way study student environments. Specifically, a is modeled autonomous agent who acts either tutor...
This paper provides a method for comprehensive evaluation and analysis of walkways in urban areas. The Xidawang Road Beigongda are taken as an example. Pedestrians' responses on the improvement current collected by questionnaire. entropy weight index system is used quantitative analysis, which includes five aspects: hardware, aesthetics, comfort, security, convenience. A total 15 indicators set. technical conditions sections were divided into grades ("excellent," "good," "medium,"...
Introduction: Hypertriglyceridemia-induced acute pancreatitis (HTG-AP) represents approximately 1-4% of all (AP) cases, and is known to have a more severe clinical presentation. A prompt diagnosis vital while managing HTG-AP, as the timely initiation triglyceride (TG)-lowering treatment could rapidly resolve etiology change course. This study aims at exploring diagnostic prognostic value hyponatremia in this patient population. Methods: We retrospectively compared 140 patients with HTG-AP...