- Liver Disease Diagnosis and Treatment
- Lipid metabolism and disorders
- Diet, Metabolism, and Disease
- Cardiovascular Disease and Adiposity
Shahid Beheshti University of Medical Sciences
2023-2024
This study was designed to investigate the possible effect of insulin receptor substrate 1
Nonalcoholic fatty liver disease (NAFLD) is a significant health issue worldwide. This study investigated the effect of adiponectin receptor 1 gene (
Abstract Objective Nonalcoholic fatty liver disease (NAFLD), which is an emerging global chronic disease, has a close association with insulin resistance. We aimed to determine whether the Gly1057Asp (rs1805097) polymorphism of receptor substrate 2 (IRS2) gene associated NAFLD. Methods Using polymerase chain reaction-restriction fragment length method, 135 patients biopsy-proven NAFLD and controls underwent IRS2 genotype analysis. Results Genotype allele distributions variant conformed...