Guangyu Cheng

ORCID: 0009-0000-4228-7597
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About
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Research Areas
  • Estrogen and related hormone effects
  • HER2/EGFR in Cancer Research
  • Neuropeptides and Animal Physiology
  • Breast Cancer Treatment Studies
  • Phytochemistry and Biological Activities
  • Covalent Organic Framework Applications
  • Medicinal Plants and Neuroprotection
  • Tryptophan and brain disorders
  • Advanced Photocatalysis Techniques
  • Computational Drug Discovery Methods
  • Apelin-related biomedical research
  • Cholinesterase and Neurodegenerative Diseases
  • Pain Mechanisms and Treatments
  • Chemical Synthesis and Reactions
  • Pharmacogenetics and Drug Metabolism
  • Phytochemicals and Antioxidant Activities
  • Phytochemical Studies and Bioactivities
  • Hormonal Regulation and Hypertension
  • Retinoids in leukemia and cellular processes
  • Stress Responses and Cortisol
  • Trigeminal Neuralgia and Treatments

Zhejiang University of Technology
2024

Weatherford College
2024

First Affiliated Hospital of Heilongjiang University of Chinese Medicine
2024

Heilongjiang University of Chinese Medicine
2023

Jiangxi University of Traditional Chinese Medicine
2023

Karolinska Institutet
2004-2005

Whilst oestrogen receptor (ER)-alpha and ERbeta have been shown to be important in the development of mammary gland, cell-specific expression pattern these two receptors within human breast is not clear. Although it well established that developing rodent gland stromal ERalpha mediates secretion growth factors which stimulate proliferation ductal epithelium, adult fibroblasts controversial, has properly defined. In present study, we evaluated by immunohistochemistry normal tissue samples,...

10.1677/jme.0.0330035 article EN Journal of Molecular Endocrinology 2004-08-01

Acori Tatarinowii Rhizoma (ATR) and Nardostahyos Radix et (NRR) are well-known traditional Chinese medicines that have been extensively used for the treatment of epilepsy (EP). However, precise molecular mechanism ATR-NRR action remains unclear because their intricate ingredients. This study aimed to investigate underlying in EP using network pharmacology docking techniques. Herbal medicine disease gene databases were searched determine active constituents shared targets EP. A...

10.1097/md.0000000000037224 article EN cc-by-nc Medicine 2024-02-09

This investigation aims to elucidate the novel role of Stromal Interaction Molecule 1 (STIM1) in modulating store-operated calcium entry (SOCE) and its subsequent impact on inflammatory cytokine release T lymphocytes, thereby advancing our understanding trigeminal neuralgia (TN) pathogenesis. Employing Gene Expression Omnibus (GEO) database, we extracted microarray data pertinent TN identify differentially expressed genes (DEGs). A comparison with SOCE-related from Genecards database helped...

10.3389/fnmol.2024.1391189 article EN cc-by Frontiers in Molecular Neuroscience 2024-06-19

There is compelling evidence from transgenic mouse studies and analysis of mutations in human carcinomas indicating that the TGF-β signal transduction pathway tumor suppressive.We have shown overexpression TGF-β1 mammary epithelial cells suppresses development expression a dominant negative type II receptor (DNIIR) under control MMTV promoter/enhancer increases incidence carcinomas.Studies tumors demonstrated inactivating genes encoding proteins involved transduction, including DPC4/Smad4,...

10.1186/bcr1054 article EN cc-by Breast Cancer Research 2005-06-01
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