About
Contact & Profiles
A5044533072
Research Areas
- Dermatological and COVID-19 studies
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
National Heart Lung and Blood Institute
2023
National Institutes of Health
2023
Abstract SARS-CoV-2 is a novel coronavirus responsible for the COVID-19 pandemic. Its high pathogenicity due to spike protein (S protein) contacting host-cell receptors. A critical hallmark of occurrence coagulopathies. Here, we report direct observation interactions between S and platelets. Live imaging shows that triggers platelets deform dynamically, in some cases, leading their irreversible activation. Cellular cryo-electron tomography reveals dense decorations on platelet surface,...
10.1038/s41467-023-36279-5
article
EN
cc-by
Nature Communications
2023-02-04
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