A5102792733- Antimicrobial Peptides and Activities
- Zeolite Catalysis and Synthesis
- Cancer-related gene regulation
- Organ Transplantation Techniques and Outcomes
- Chemical Synthesis and Analysis
- Catalysis and Hydrodesulfurization Studies
- Mesoporous Materials and Catalysis
- Immune Cell Function and Interaction
- Cytomegalovirus and herpesvirus research
- T-cell and B-cell Immunology
- Liver Disease and Transplantation
- MicroRNA in disease regulation
- RNA Interference and Gene Delivery
- Nanoplatforms for cancer theranostics
- Cancer-related molecular mechanisms research
- Ubiquitin and proteasome pathways
- TGF-β signaling in diseases
- Chemokine receptors and signaling
Second People Hospital of Hunan
2024
Jilin University
2004-2024
University of Hong Kong - Shenzhen Hospital
2021
University of Hong Kong
2016-2021
Graphical abstractAbstractBackground & AimsLiver graft injury and tumor recurrence are the major challenges of liver transplantation for patients with hepatocellular carcinoma (HCC). Here, we aimed to explore role mechanism mobilizing regulatory T cells (Tregs), which lead late phase after transplantation.MethodsThe correlation among recurrence, Tregs mobilization were studied in 257 transplant recipients HCC orthotopic rat models. The direct roles CXCL10/CXCR3 signaling on investigated...
The development of responsive and smart drug nanocarriers that defeat the tumor microenvironment resists cancer therapy has attracted considerable attention in recent decades. Upgrades are sought to effectively increase therapeutic efficacy chemotherapy drugs reduce damage normal tissues. In this study, a new type silica nano-particle carrier, dual-functionalized mesoporous nanobeans (DF-MSNB), is used encapsulate drug, doxorubicin (DOX), form DOX@DF-MSNB complex. complex simultaneously...
To investigate the expression of Inhibin B between various clinical stages, Chinese medicine dialectic typing, and in nasopharyngeal carcinoma (NPC) tissues serum, to evaluate potential as a new biomarker for NPC. Paraffin specimens pathologically confirmed NPC paracancerous were retrospectively collected, α (INHA) βB (INHBB) was detected by SP method, their relationship with clinicopathological indexes analyzed; addition, patients who had received radiotherapy included study subjects,...
The interplay between cytomegalovirus (CMV) latency and graft malfunction after living donor liver transplantation remains poorly defined because of the complexity clinical confounding factors. Here, we aimed to investigate effects CMV on small-for-size injury get further insight into pathogenic role hepatic stellate cells (HSCs) in this process.Rat orthotopic with grafts was performed a latent model developed immunocompetent Sprague Dawley rats using Priscott strain. Posttransplant...