- Cancer and Skin Lesions
- Immunotherapy and Immune Responses
- Immune cells in cancer
- Soft tissue tumor case studies
- Genetic and rare skin diseases.
- Autoimmune Bullous Skin Diseases
- Eosinophilic Disorders and Syndromes
- Genital Health and Disease
- Nonmelanoma Skin Cancer Studies
- Histiocytic Disorders and Treatments
- Phagocytosis and Immune Regulation
- Nail Diseases and Treatments
- Vascular Tumors and Angiosarcomas
- Sarcoma Diagnosis and Treatment
- Cutaneous Melanoma Detection and Management
- Dermatological and Skeletal Disorders
- Salivary Gland Tumors Diagnosis and Treatment
- Medicine and Dermatology Studies History
- Urologic and reproductive health conditions
- Cutaneous lymphoproliferative disorders research
- Ear and Head Tumors
- Tumors and Oncological Cases
- RNA Interference and Gene Delivery
- Skin and Cellular Biology Research
- Autoimmune and Inflammatory Disorders
University of the Philippines System
2024
Galveston College
1986-2022
The University of Texas Medical Branch at Galveston
1997-2020
VA Long Beach Healthcare System
2009
Long Beach Medical Center
2001-2008
California State University, Long Beach
2002-2005
University of California, Irvine
2001-2005
Houston Methodist
1988-2002
Hospital General Universitario de Albacete
1998
University of Louisville
1997
Reactive angioendotheliomatosis (RA) is a rare, benign disease. Affected patients present with self‐limited, erythematous to violaceous plaques. The clinical lesions are due intravascular hyperplasia of cytologically banal endothelial cells in the dermis. We report 2 who presented ulcerated, plaques on lower extremities. Both had severe peripheral vascular atherosclerotic disease requiring bypass grafts. Unlike previously described cases RA, our patient's were diffuse proliferation reticular...
Abstract: We saw two newborn infants with striated muscle hamartoma. One patient had numerous associated congenital anomalies. The clinical appearance of both lesions was that a soft fibroma. Histologically, fibers and nerve bundles were seen in the central core also at periphery lesion, below epidermis. A marked number sebaceous glands, vellus hair follicles, eccrine glands present. propose term hamartoma, which points out most remarkable feature these lesions.
Extramammary Paget disease (EPD) is an uncommon cutaneous malignant neoplasm that arises in areas rich apocrine glands (perineum, vulva, and axilla). Apocrine gland origin or differentiation of cells EPD has been suggested. Estrongen, progesterone, androgen hormone receptors have reported to exhibit a characteristic pattern expression mammary type carcinomas; however, their not elucidated fully. By using immunohistochemical methods, we studied the steroid on formalin-fixed paraffin-embedded...
Nodular fasciitis is a benign reactive myofibroblastic proliferative process of unknown etiology. It presents as solitary painless, rapidly growing nodule over several weeks' duration. The condition self-limited, and proper diagnosis essential to avoid unnecessary aggressive treatment. Diagnosis often challenge because it may be confused with malignant tumor due its clinical behavior histological features. Immunohistochemical staining can useful tool aid in the diagnosis. Although most...
This study determined whether genomic amplification of HER-2/neu or mutations the p53 and ras genes were present in gastrinomas.Amplification HER-2/neu, a proto-oncogene related to epidermal growth factor receptor, mutation tumor suppressor gene appear play role pathogenesis some human cancers. Little is known about possible molecular alterations gastrinomas, tumors that may be particularly virulent because gastrin overproduction, resulting severe ulcer diathesis, Zollinger-Ellison...
No AccessJournal of UrologyClinical Urology: Original Articles1 Jun 1998GRANULOMATOUS EPIDIDYMO-ORCHITIS: SONOGRAPHIC FEATURES AND CLINICAL OUTCOME IN BRUCELLOSIS, TUBERCULOSIS IDIOPATHIC GRANULOMATOUS EPIDIDYMO-ORCHITIS ISABEL SALMERON, MARIA-ANGELES RAMIREZ-ESCOBAR, FELISA PUERTAS, ROSA MARCOS, FAUSTO GARCIA-MARCOS, and RAMON SANCHEZ SALMERONISABEL SALMERON , RAMIREZ-ESCOBARMARIA-ANGELES RAMIREZ-ESCOBAR PUERTASFELISA PUERTAS MARCOSROSA MARCOS GARCIA-MARCOSFAUSTO GARCIA-MARCOS SANCHEZRAMON...
Sebaceous gland neoplasms are rare tumors that associated with visceral malignancies in patients Muir-Torre syndrome (MTS). The majority of the MTS-associated reveal mutations DNA mismatch repair (MMR) genes (most often hMSH-2 and hMLH-1) microsatellite instability. sebaceous lesions MTS can precede or occur concurrently neoplasms. early recognition those their differentiation from sporadic critical for proper patient management. Here we investigate MMR gene expression a variety tumors,...
• Electron microscopic examination in a case of papular xanthoma revealed the presence myelinlike laminated bodies cytoplasm foam cells. To our knowledge, similar have been described large numbers only two cases congenital self-healing histiocytosis and one generalized eruptive histiocytoma. The may be morphologic characteristic xanthoma. However, this possibility should confirmed by identification same inclusions other disease. (<i>Arch Dermatol</i>1985;121:626-631)
Eleven cases of sinus histiocytosis with massive lymphadenopathy (SHML) involving lymph nodes were studied electron microscopically. Histiocytes the most conspicuous element infiltrate. They could be divided into small and large forms, although transitions apparent among them. Most histiocytes located in medullary cords. The predominantly seen within sinuses subdivided two types on basis their appearance. distinctive feature these was presence lymphocytes, plasma cells, neutrophils...
No AccessJournal of UrologyClinical Urology: Case Report1 Jun 1995Development Human Papillomavirus Type 16 Associated Squamous Cell Carcinoma the Scrotum in a Patient with Darier's Disease Treated Systemic Isotretinoin Eduardo Orihuela, Stephen K. Tyring, Mariela Pow-Sang, Susan Dozier, Richard Cirelli, Istvan Arany, Peter Rady, and Ramon Sanchez OrihuelaEduardo Orihuela , TyringStephen Tyring Pow-SangMariela Pow-Sang DozierSusan Dozier CirelliRichard Cirelli AranyIstvan Arany RadyPeter Rady...
Among all patients with a pathologic diagnosis of juvenile xanthogranuloma (JXG) seen at our institution from 1983 to 1994, we identified five an unusual histologic pattern that differed the classic (CJXG) foamy cells and Touton giant cells. Four these cases, which termed nonlipidized (NJXG), were in infants. The features include monomorphic infiltrate absent or few foam There is little inflammation, mitotic figures are easily found. cases exhibit diffuse sheetlike while one trabecular....
Hepatocellular carcinoma is a lethal disease and methods that develop effective cellular-based immunotherapy are needed. We retrovirally transduced non-immunogenic mouse Hepa1-6 hepatoma cells with the gene encoding membrane form of macrophage colony stimulating factor (mM-CSF). Excess recombinant M-CSF phagocytosis-inhibiting chemicals blocked macrophage-mediated killing cloned mM-CSF transfected cells. Macrophages derived from Hck−/−Fgr−/− Lyn−/− triple knockout mice, which incapable...