About
Contact & Profiles
A5014981599
Research Areas
- Ubiquitin and proteasome pathways
- Genomics and Chromatin Dynamics
- Protein Degradation and Inhibitors
- RNA and protein synthesis mechanisms
Stanford University
2022-2023
10.1038/s41586-023-05906-y
article
EN
Nature
2023-04-05
Summary Human gene expression is regulated by over two thousand transcription factors and chromatin regulators 1,2 . Effector domains within these proteins can activate or repress transcription. However, for many of we do not know what type transcriptional effector they contain, their location in the protein, activation repression strengths, amino acids that are necessary functions. Here, systematically measure activity >100,000 protein fragments (each 80 long) tiling across most human...
10.1101/2022.08.26.505496
preprint
EN
cc-by-nc
bioRxiv (Cold Spring Harbor Laboratory)
2022-08-26
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