A5036834366- Neuroscience and Neuropharmacology Research
- Neuroscience of respiration and sleep
- Neuropeptides and Animal Physiology
- Neurotransmitter Receptor Influence on Behavior
- Robotic Locomotion and Control
- Robot Manipulation and Learning
- Obstructive Sleep Apnea Research
- Receptor Mechanisms and Signaling
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Semiconductor materials and devices
- Respiratory Support and Mechanisms
- Silicon Carbide Semiconductor Technologies
- Neurogenesis and neuroplasticity mechanisms
- Pulmonary Hypertension Research and Treatments
- Biochemical effects in animals
- Sleep and Wakefulness Research
- Neuroendocrine regulation and behavior
- Neuroinflammation and Neurodegeneration Mechanisms
- High Altitude and Hypoxia
- Schizophrenia research and treatment
- Adipose Tissue and Metabolism
- Nitric Oxide and Endothelin Effects
- Nerve injury and regeneration
- Control and Dynamics of Mobile Robots
- Regulation of Appetite and Obesity
Gifu University
2024-2025
Chiba University
2013-2024
International University of Health and Welfare
1996-2024
Nippon Medical School
2017-2024
Tsubakimoto Chain (Japan)
2024
Imamura Hospital
2023
Fukujuji Hospital
2020-2022
Japan Anti Tuberculosis Association
2021-2022
Nagasaki University
2002-2021
Nara Medical University
2009-2021
Abstract An atlas of the distribution cholinergic cell bodies, fibers, and terminals, as well cholinoceptive cells, in central nervous system cat (excluding cerebellum) is presented from results obtained immunohistochemical work on choline acetyltransferase. Cholinergic bodies are observed more than forty areas, cells sixty discrete areas brain sections spinal cord to olfactory bulb. The seventy cross‐sectional drawings extending bulb upper cervical cord.
We have been trying to induce a quadruped robot walk with medium walking speed on irregular terrain based biological concepts. propose the necessary conditions for stable dynamic in general, and we design mechanical system neural by comparing concepts those described physical terms. A PD controller at joints can construct virtual spring-damper as visco-elasticity model of muscle. The consists central pattern generator (CPG) reflexes. CPG receives sensory input changes period its own active...
The paper reports on a project to make quadruped robot walk with medium forward speed irregular terrain in an outdoor environment using neural system model. necessary conditions for stable dynamic walking general are proposed, and the is designed by comparing biological concepts those described physical terms. A PD-controller used at joints construct virtual spring—damper as visco-elasticity model of muscle. consists CPG (central pattern generator), responses reflexes. response directly...
Choline acetyltransferase was demonstrated in neuronal structures of the rodent central nervous system by immunohistochemistry through application Fab fragments obtained from monospecific antiserums to human choline acetyltransferase. The specificity antiserum for enzyme confirmed staining both ventral horn motor neurons rat spinal cord and neuromuscular junction guinea pig diaphragm. Enzyme-containing cell bodies were observed frontal sections brain neostriatum, accumbens, nucleus diagonal...
Abstract We assayed guanylate cyclase activity in preparations of heart and other rat tissues. Enzymatic was found both particulate supernatant fractions homogenates from a number different tissues, the distribution varied with tissue examined. All tissues studied, however, had significant amount associated fraction. In about equally divided between 1,000 x g 100,000 small amounts fractions. The two apparently enzymatic activities were separable gel filtration due to their dissimilar sizes....
Abstract Postmortem counts of dopaminergic cell densities in the substantia nigra (5 subjects) and striatal levels dopamine (DA) its metabolites (6 were determined on 1 parkinsonian (PD), 3 progressive supranuclear palsy (PSP), amyotrophic lateral sclerosis, Alzheimer's case who had been positron emission tomography scanned with 6‐[ 18 F]fluorodopa during life. [ F]Fluorodopa uptake rate constants, which presumably depend number functioning DA terminals, strictly proportional to (significant...
Summary: Purpose : Mitogenic effects of seizures on granule cell progenitors in the dentate gyrus were studied two rat models epilepsy. We investigated which stage epileptogenesis is critical for eliciting progenitor division and whether seizure‐induced neuronal degeneration responsible enhancement division. Methods Seizures induced by either kainic acid (KA) administration or electrical kindling. Neurogenesis cells was evaluated using bromodeoxyuridine (BrdU) labeling method, assessed situ...
Abstract —In the hypothalamus, highest GABA content (approx. 26 nmol/mm 3 ) was constantly observed in lateral hypothalamic area (LHA). In other parts of hypothalamus uneven distribution also observed, but areas showing high concentration did not coincide with locations various nuclei. LHA, which is known to contain a feeding centre, anterior part (6.4 and 6.0 mm (A 6.4 A 6.0) respectively vertical zero plane de Groot) showed remarkably GABA. The LHA at decreased during initial phase insulin...
Background Pulmonary cachexia is common in advanced chronic obstructive pulmonary disease (COPD), culminating exercise intolerance and a poor prognosis. Ghrelin novel growth hormone (GH)-releasing peptide with GH-independent effects. The efficacy safety of adding ghrelin to rehabilitation (PR) cachectic COPD patients were investigated. Methodology/Principal Findings In multicenter, randomized, double-blind, placebo-controlled trial, 33 randomly assigned PR intravenous (2 µg/kg) or placebo...
The trend of the initial treatment strategy for pulmonary arterial hypertension (PAH) has changed from monotherapies to upfront combination therapies. This study analyzed treatments and outcomes in Japanese patients with PAH, using data Japan PH Registry (JAPHR), which is first organized multicenter registry PAH Japan.
When a horizontal electric field is applied, the sedimentation velocity of particles increases, phenomenon known as Electrically Induced Rapid Separation (ERS). Hollow with lower density than water exhibit an increased flotation under field. This study investigates ERS effect in mixed suspensions containing denser and hollow density. In absence field, settle while float, their behavior independent ratio to total number (α). However, when DC 0.4 V/mm becomes dependent on α. For α < ~0.90,...
We examined changes in brain waves and blood levels of serum Cortisol during yoga exercise 7 instructors found that alpha increased decreased. These two measures were negatively correlated ( r = -.83). Comparison with a control group nonpractitioners is desirable.
Postnatal serotonin (5HT) innervation in the cerebral cortex of mice has been studied by 5HT immunohistochemistry. 5HT-like immunoreactive (5HT-LI) nerve fibers and terminals appeared to increase transiently, particularly somatosensory (Sm) during early postnatal days. As pups grow, afferent inputs decreased rapidly reach a similar pattern distribution that adult animals. Since transient was seen at critical period (seventh day) for differentiation layer IV, it is suggested increased...
Abstract Glial fibrillary acidic protein (GFA) has been visualized by direct peroxi‐dase antiperoxidase (PAP) immunohistochemistry in various vertebrates (cyclostomes, teleosts, amphibians, reptiles, birds, and several placental mammals). In this study GFA‐immunoreactivity (GFA‐I) was observed all species examined except cyclostomes amphibians. Two types of immunoreactive elements were observed: astrocytes long processes without visible somata. Astrocytic cells with GFA‐I first found the...
Ghrelin, a novel growth hormone-releasing peptide, has been shown to cause positive energy balance by reducing fat use and stimulating food intake. This study investigated whether plasma ghrelin is associated with clinical parameters in patients chronic obstructive pulmonary disease. Plasma was measured 50 13 control subjects, together anabolic catabolic factors. Patients were divided into two groups based on body mass index: underweight (n = 26) or normal weight 24). significantly higher...
Cholinergic afferents to the amygdala from basal forebrain were studied using di-isopropyl fluorophosphate-AChE histochemistry in combination with retrograde tracing various fluorescent dyes. Cells sending their axons and staining intensely for AChE located mainly nucleus of substantia innominata. They also found ventral part globus pallidus, horizontal limb tractus diagonalis Broca, interstitialis ansae lenticularis. A correspondence was established between these cells choline...