Melese Legesse Mitku

ORCID: 0009-0001-1515-3400
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About
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Research Areas
  • Pharmaceutical Practices and Patient Outcomes
  • Cancer therapeutics and mechanisms
  • Pharmaceutical studies and practices
  • Pharmaceutical Economics and Policy
  • Synthesis and biological activity
  • Chronic Disease Management Strategies
  • Synthesis and bioactivity of alkaloids
  • Identification and Quantification in Food
  • Intellectual Property and Patents
  • Sexual function and dysfunction studies
  • Poxvirus research and outbreaks
  • Bacillus and Francisella bacterial research
  • Patient Safety and Medication Errors
  • Migration, Health and Trauma
  • Malaria Research and Control
  • Pharmaceutical Quality and Counterfeiting
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Posttraumatic Stress Disorder Research
  • Trypanosoma species research and implications
  • Reproductive Health and Contraception
  • Pharmacological Effects and Toxicity Studies
  • Spectroscopy and Chemometric Analyses
  • Health and Conflict Studies
  • Zoonotic diseases and public health
  • Pneumonia and Respiratory Infections

University of Gondar
2020-2025

Abstract Tuberculosis (TB) remains a significant public health concern, particularly in low-resource settings. The treatment outcome is crucial indicator of the effectiveness TB programs. Assessing current and its associated factors essential for improving patient care reducing spread TB. Therefore, this study aimed to assess outcomes their among patients who received at healthcare facilities Motta Town, Northwest Ethiopia. A facility-based retrospective cross-sectional design was employed...

10.1038/s41598-024-58080-0 article EN cc-by Scientific Reports 2024-04-02

Food adulteration is the intentional addition of foreign or inferior substances to original food products for a variety reasons. It takes place in forms, like mixing, substitution, hiding poor quality packaging material, putting decomposed sale, misbranding giving false labels, and adding toxicants. Several analytical methods (such as chromatography, spectroscopy, electronic sensors) are used detect foodstuffs. This review provides concise but detailed information understand scope scale way...

10.1177/20503121241250184 article EN cc-by-nc SAGE Open Medicine 2024-01-01

Abstract Background Refugee populations are forcibly displaced from their homes as a consequence of natural disasters and armed conflicts. Eritreans, initially to the Maiayni camp within Tigray region, have faced further relocation Dabat town due conflict between People Liberation Front (TPLF) Ethiopian government forces. Subsequently, another has arisen Amhara Popular Force (Fano) forces in town, disrupting its stability. These collective challenges new environment may contribute...

10.1186/s40359-024-01554-7 article EN cc-by BMC Psychology 2024-02-07

Background Healthcare workers are on the frontlines of fighting health risks, especially during epidemics. Despite their critical role, knowledge and attitudes toward Mpox have not been previously evaluated at University Gondar Comprehensive Specialized Hospital, Ethiopia. This study aimed to assess healthcare regarding this hospital. Method cross-sectional assessing 382 HCWs. It was conducted August 1–30, 2024. Data collected using a self-administered questionnaire. A simple random sampling...

10.3389/fpubh.2025.1527315 article EN cc-by Frontiers in Public Health 2025-03-03

Pharmaceutical waste (PW) generated in health facilities includes expired or unused medications, contaminated materials, and other pharmaceutical residues from diagnosis, treatment, immunization, compounding, manufacturing. PW management (PWM) is critical for environmental protection public health. Therefore, this study aimed to evaluate of at hospitals community pharmacies Bahir Dar Gondar cities, Ethiopia. A facility-based cross-sectional was conducted private cities July 2023 September...

10.1186/s12913-025-12555-6 article EN cc-by-nc-nd BMC Health Services Research 2025-03-14

Background: Hyperemesis gravidarum is one of the problems encountered among pregnant women due to persistent and excessive vomiting starting before end 22nd week gestation. The current study aimed assess prevalence hyperemesis associated factors at comprehensive specialized hospitals in northwest Ethiopia. Methods: A multi-facility-based cross-sectional was conducted from 1st June 2022 30th July 2022. data were entered using EPI Data Version 4.6 statistical software analyzed SPSS 26....

10.1177/20503121241257163 article EN cc-by-nc SAGE Open Medicine 2024-01-01

In silico predictions are now being utilized in drug discovery and design to assess the physicochemical, pharmacokinetics, safety properties of compounds at beginning process. This early evaluation helps researchers invest their time resources only best prospective lead by eliminating with a low chance success.

10.1177/20503121241274212 article EN cc-by-nc SAGE Open Medicine 2024-01-01

Background Poor sleep quality is a common concern in chronic kidney disease (CKD) patients, which can accelerate the progression of renal and negatively impact their health-related life, potentially leading to greater morbidity mortality rates. It also have an effect on immune system, cognitive function, emotional well-being CKD patients. Furthermore, poor may contribute drug noncompliance decreased participation entire treatment plan. Nonetheless, no research has been undertaken Ethiopia...

10.3389/fmed.2024.1366010 article EN cc-by Frontiers in Medicine 2024-05-01

Pharmacy services in hospitals are designed to meet the needs of all patients. This is undoubtedly one most complex provided by hospitals. In government hospitals, including those Ethiopia, pharmacies mainly serve as drug stores and dispensaries. To best our knowledge, this study first assess ensure better quality assurance for hospital pharmacy Ethiopia. Therefore, objective article was current status

10.1177/20503121241272738 article EN cc-by-nc SAGE Open Medicine 2024-01-01

Pharmaceutical compounding, a practice of tailoring medications to individual patient needs, is integral healthcare but poses potential risks, including adverse drug events (ADEs) and antimicrobial resistance (AMR). Understanding professionals' knowledge perceptions on these issues crucial for enhancing safety. This study aimed assess the professionals regarding contribution inappropriate pharmaceutical compounding ADEs AMR at Pawi General Hospital in Metekel Zone, Benishangul-Gumuz Region....

10.1007/s44250-024-00133-2 article EN cc-by-nc-nd Discover Health Systems 2024-08-16

Access to cardiovascular medications is severely hampered by their unavailability and high cost, particularly for the poorest households in developing nations. The availability price range of are significantly limited both hospital community pharmacies.

10.1155/2024/6551639 article EN cc-by BioMed Research International 2024-01-01
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