Private record linkage (PRL) is the problem of identifying pairs records that are similar as per an input matching rule from databases held by two parties do not trust one another. We identify three key desiderata a PRL solution must ensure: (1) perfect precision and high recall pairs, (2) proof end-to-end privacy, (3) communication computational costs scale subquadratically in number records. show all existing solutions for PRL? including secure 2-party computation (S2PC), their variants...

Abstract: The main objective of this study was to determine whether the excitotoxic cholinesterase inhibitor soman increases catabolism phospholipids in rat brain. Injections (70 μg/kg, s.c), at a dose that produced toxic effects, increased levels both free fatty acids (175–250% control) and choline (250% cerebrum 1 h after administration. All contained brain phosphatidylcholine were elevated significantly including palmitic (16:0), stearic (18:0), oleic (18:1), arachidonic (20:4),...

It has been shown that AIC-type criteria are asymptotically efficient selectors of the tuning parameter in non-concave penalized regression methods under assumption population variance is known or a consistent estimator available. We relax this to prove AIC itself and we study its performance finite samples. In classical regression, it tends select overly complex models when dimension maximum candidate model large relative sample size. Simulation studies suggest suffers from same...

Male and female guinea pigs receiving, respectively, 100 280 mg/day Vitamin C throughout the duration of immunization showed enhanced humoral antibody production to bovine serum albumin (BSA) and, in castrated females, penicilloyl-coupled pig gamma-globulin. A significant degree protection was afforded against fatal anaphylactic shock passively sensitized males. Under appropriate conditions sensitization with rabbit anti-HGG challenge human gamma-globulin, 8 20 unsupplemented animals died...

Many complex natural and technological systems are commonly modeled as count-weighted graphs, where nodes represent entities, edges model relationships between them, edge weights define some counting statistics associated with each relationship. As graph data usually contain sensitive information about preserving privacy when releasing this type of becomes an important issue. In context, differential (DP) has become the de facto standard for release under strong guarantees. When dealing DP...

The Lasso is a computationally efficient regression regularization procedure that can produce sparse estimators when the number of predictors (p) large. Oracle inequalities provide probability loss bounds for estimator at deterministic choice parameter. These tend to zero if p appropriately controlled, and are thus commonly cited as theoretical justification its ability handle high-dimensional settings. Unfortunately, in practice parameter not selected be quantity, but instead chosen using...

Biclustering, the process of simultaneously clustering rows and columns a data matrix, is popular effective tool for finding structure in high-dimensional dataset. Many biclustering procedures appear to work well practice, but most do not have associated consistency guarantees. To address this shortcoming, we propose new procedure based on profile likelihood. The applies broad range modalities, including binary, count, continuous observations. We prove that recovers true row column classes...

The objective of this study was to determine the role hilar nerve (lung vagal) afferents in hyperpnea exercise. Ten ponies were studied before and 2–4 wk 3–12 mo after sectioning only branches vagus nerves (HND). After HND, lung volume feedback medullary centers attenuated as indicated anesthetized state by 1) attenuation or absence Hering-Breuer inflation reflex (P less than 0.01) 2) lengthened inspiratory time (TI) when airway occluded at end expiration 0.01). Moreover, HND awake state,...

Private record linkage (PRL) is the problem of identifying pairs records that are similar as per an input matching rule from databases held by two parties do not trust one another. We identify three key desiderata a PRL solution must ensure: 1) perfect precision and high recall pairs, 2) proof end-to-end privacy, 3) communication computational costs scale subquadratically in number records. show all existing solutions for - including secure 2-party computation (S2PC), their variants use...

In this report, we describe the fractionation of crude axolemmal fractions from rat lower brainstem into subfractions enriched in markers for either periaxolemmal myelin or axolemma. These were isolated on density gradients as bands layering 0.8M and 1.0M sucrose. Both consisted unilamellar vesicles. Relative to purified same starting material, subfraction was MAG, CNPase, carbonic anhydrase Na+, K+ ATPase but extremely low PLP MBP. addition, fraction exhibited a protein profile distinct...

Differential privacy is the state-of-the-art formal definition for data release under strong guarantees. A variety of mechanisms have been proposed in literature releasing noisy output numeric queries (e.g., using Laplace mechanism), based on notions global sensitivity and local sensitivity. However, although there has some work generic non-numeric Exponential lacks to reduce noise query output. In this work, we remedy shortcoming present dampening mechanism. We adapt notion setting leverage...

We assessed the consequences of respiratory unloading associated with tracheostomy breathing (TBr). Three normal and three carotid body-denervated (CBD) ponies were prepared chronic tracheostomies that at rest reduced physiological dead space (VD) from 483 +/- 60 to 255 30 ml lung resistance 1.5 0.14 0.5 0.07 cmH2O . l-1 s. At during steady-state mild-to-heavy exercise arterial PCO2 (PaCO2) was approximately 1 Torr higher nares (NBr) than TBr. Pulmonary ventilation tidal volume (VT) greater...

Differential privacy is the state-of-the-art formal definition for data release under strong guarantees. A variety of mechanisms have been proposed in literature releasing output numeric queries (e.g., Laplace mechanism and smooth sensitivity mechanism). Those guarantee differential by adding noise to true query's output. The amount added calibrated notions global local query that measure impact addition or removal an individual on Mechanisms use add less and, consequently, a more accurate...

The objective of this study was to determine whether changes in limb motion per se influence arterial CO2 partial pressure (PaCO2) during muscular exercise ponies. Fifteen ponies were studied at rest and 8 min treadmill when the work load constant or increased after 4th min. Five different settings selected provide for a range metabolic rate achieved with primary either speed grade (1.8 mph 3, 8, 15% grade; 3 6 3% grade). exercised on all four legs only hindlegs. Step frequencies 49, 66, 99...

Carotid body-denervated (CBD) ponies have a less than normal increase in arterial PCO2 (PaCO2) when inspired CO2 (PICO2) is increased, even pulmonary ventilation (VE) and breathing frequency (f) are normal. We studied six tracheostomized to determine whether this change 1) might be due increased alveolar (VA) secondary reduction upper airway dead space (VD) or 2) dependent on an sensory mechanism. Three three chronic CBD were while they room air at 14, 28, 42 Torr PICO2. While the air,...