A5058817882- 3D Printing in Biomedical Research
- Additive Manufacturing and 3D Printing Technologies
- Cancer Cells and Metastasis
- Biomedical Ethics and Regulation
- Neuroinflammation and Neurodegeneration Mechanisms
- Microfluidic and Capillary Electrophoresis Applications
- Innovative Microfluidic and Catalytic Techniques Innovation
- Immune cells in cancer
- Single-cell and spatial transcriptomics
- Immune Response and Inflammation
University of Wisconsin–Madison
2022-2024
University of Wisconsin Carbone Cancer Center
2023
Highland Community College - Illinois
2023
As a leading cause of mortality and morbidity, stroke constitutes significant global health burden. Ischemic accounts for 80% cases occurs due to an arterial thrombus, which impedes cerebral blood flow rapidly leads cell death. the most abundant type within central nervous system, astrocytes play critical role injured brain. We developed novel microphysiological platform that permits induction spatiotemporally controlled nutrient gradients, allowing us study astrocytic response during after...
Abstract Biological tissues are highly organized structures where spatial-temporal gradients (e.g., nutrients, hypoxia, cytokines) modulate multiple physiological and pathological processes including inflammation, tissue regeneration, embryogenesis, cancer progression. Current in vitro technologies struggle to capture the complexity of these transient microenvironmental gradients, do not provide dynamic control over gradient profile, complex poorly suited for high throughput applications....
For patients with end stage organ failure, transplant is frequently the only curative option available. However, organs available for are in critically short supply around world, which has led to lengthy wait times and increased mortality. Increased global life expectancy, coupled raised age thresholds recipients, heightened demand further compounded need alternative strategies. Bioengineering substitutes including organ-on-a-chip 3D bioprinting technologies have made considerable strides...