Méritxell Fillols

ORCID: 0009-0001-3603-0389
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About
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Research Areas
  • Radical Photochemical Reactions
  • Chemical Synthesis and Analysis
  • Advanced Photocatalysis Techniques
  • Catalytic Cross-Coupling Reactions
  • Advanced biosensing and bioanalysis techniques
  • Crystallization and Solubility Studies
  • Chemical Synthesis and Reactions
  • Porphyrin and Phthalocyanine Chemistry
  • Organic Electronics and Photovoltaics
  • Innovative Microfluidic and Catalytic Techniques Innovation
  • X-ray Diffraction in Crystallography
  • Ammonia Synthesis and Nitrogen Reduction
  • Photochromic and Fluorescence Chemistry
  • Catalytic C–H Functionalization Methods

University of Amsterdam
2024

Chalmers University of Technology
2019

Abstract Unnatural amino acids, and their synthesis by the late‐stage functionalization (LSF) of peptides, play a crucial role in areas such as drug design discovery. Historically, LSF biomolecules has predominantly utilized traditional synthetic methodologies that exploit nucleophilic residues, cysteine, lysine or tyrosine. Herein, we present photocatalytic hydroarylation process targeting electrophilic residue dehydroalanine (Dha). This possesses an α , β ‐unsaturated moiety can be...

10.1002/anie.202403271 article EN cc-by Angewandte Chemie International Edition 2024-03-18

Devices that can capture and convert sunlight into stored chemical energy are attractive candidates for future technologies. A general challenge is to combine efficient solar with high densities storage time a processable composite device application. Here, norbornadiene (NBD)-quadricyclane (QC) molecular photoswitches embedded polymer matrices, possible applications in storing coatings. The NBD-QC capable of absorbing estimated efficiencies up 3.8% combined 0.48 MJ kg

10.1002/advs.201900367 article EN cc-by Advanced Science 2019-04-25

Abstract Unnatural amino acids, and their synthesis by the late‐stage functionalization (LSF) of peptides, play a crucial role in areas such as drug design discovery. Historically, LSF biomolecules has predominantly utilized traditional synthetic methodologies that exploit nucleophilic residues, cysteine, lysine or tyrosine. Herein, we present photocatalytic hydroarylation process targeting electrophilic residue dehydroalanine (Dha). This possesses an α , β ‐unsaturated moiety can be...

10.1002/ange.202403271 article EN cc-by Angewandte Chemie 2024-03-18

The development of robust and reliable methods for the construction C(sp2)–C(sp3) bonds is vital accessing an increased array structurally diverse scaffolds in drug discovery campaigns. While significant advances towards this goal have been achieved using metallaphotoredox chemistry, many these utilise photocatalysts based on precious-metals due to their efficient redox processes tuneable properties. However, cost, scarcity, toxicity metals, search suitable replacements should be a priority....

10.26434/chemrxiv-2024-b7kv6 preprint EN cc-by 2024-03-26

Unnatural amino acids, and their synthesis via the late-stage functionalization (LSF) of peptides, play a crucial role in areas such as drug design discovery. Historically, LSF biomolecules has predominantly utilized traditional synthetic methodologies that exploit nucleophilic residues, cysteine, lysine or tyrosine. In this study, we present photocatalytic hydroarylation process targeting electrophilic residue dehydroalanine (Dha). This possesses an α,β-unsaturated moiety can be combined...

10.26434/chemrxiv-2024-6fgqv preprint EN cc-by 2024-02-14

Abstract The development of robust and reliable methods for the construction C(sp 2 )−C(sp 3 ) bonds is vital accessing an increased array structurally diverse scaffolds in drug discovery campaigns. While significant advances towards this goal have been achieved using metallaphotoredox chemistry, many these utilise photocatalysts based on precious‐metals due to their efficient redox processes tuneable properties. However, cost, scarcity, toxicity metals, search suitable replacements should...

10.1002/ange.202405902 article EN cc-by Angewandte Chemie 2024-05-29
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