A5086632045- Thermal Regulation in Medicine
- Cardiac Arrest and Resuscitation
- Thermoregulation and physiological responses
- Hallucinations in medical conditions
- Endometriosis Research and Treatment
- Olfactory and Sensory Function Studies
- Treatment of Major Depression
- Skin Protection and Aging
- Uterine Myomas and Treatments
- Thermoelastic and Magnetoelastic Phenomena
- Bone and Dental Protein Studies
- Body Contouring and Surgery
- Hemodynamic Monitoring and Therapy
- 3D Printing in Biomedical Research
- Wound Healing and Treatments
- Gynecological conditions and treatments
- Advanced Thermodynamic Systems and Engines
- IL-33, ST2, and ILC Pathways
- Traumatic Brain Injury and Neurovascular Disturbances
- Breast Implant and Reconstruction
- Lymphatic System and Diseases
- Skin Diseases and Diabetes
- Fibroblast Growth Factor Research
- Optical Imaging and Spectroscopy Techniques
- Microbial Inactivation Methods
Semtech (United States)
2021-2024
University of California, San Diego
1992-2003
Vital Therapies (United States)
2003
Columbia University
2003
CryoLife (United States)
1998-2000
Scripps Research Institute
1994
Oklahoma State University Center for Health Sciences
1987
Memorial Hospital
1987
University of California, Los Angeles
1987
Skin cancer risk is increased by exposure to ultraviolet radiation (UVR). Because UVR accumulates over time and lighter skin more susceptible UVR, age tone are factors for cancer. However, measurements of somatic mutations in healthy-appearing have not been used calculate risk. In this study, we developed a noninvasive test that quantifies sun-exposed applied it 1038-subject cohort. Somatic were combined with other known train model The final (DNA-Skin Cancer Assessment Risk) was trained...
Background and Purpose— Hypothermia has been shown to be neuroprotective in a variety of clinical settings. Unfortunately, poor delivery techniques insufficient data appropriate preclinical models have hampered its development human stroke. To address these limitations, we devised 10F intravascular catheter capable rapid systemic cooling nonhuman primates. Methods— Placed the inferior vena cava via transfemoral approach, was used induce mild hypothermia 3 hours after onset hemispheric stroke...
OBJECTIVE: This study was undertaken to assess the acute safety and feasibility of rapidly inducing, maintaining, then reversing hypothermia using a novel heat transfer catheter closed-loop automatic feedback temperature control system overcome limitations imposed by current clinical practices used for perioperative cooling warming. METHODS Six swine (mean mass, 53.8 ± 3.6 kg) were studied. The placed in inferior vena cava via femoral vein. Hypothermia 32°C induced, maintained 6 hours,...
The aim of this study was to evaluate the efficacy isoproterenol and prednisolone in treatment subcutaneous lipomas.The first experiment evaluated vitro lipolysis induced by 10(-6) M alone across a range concentrations determine optimal dose maximize lipolysis. second lipoma fat vivo microdialysis five subjects with without M. These additional had treated times week for 4 weeks 4-cm grid 0.2 ml injections prednisolone. Lipoma size followed monthly 1 year or until surgical...
There are few objective techniques to accurately measure the outcome of liposuction. Consequently, there is also a paucity data quantifying results this procedure.The authors compare changes in abdominal volume and circumference with several measurement relatively homogeneous group individuals undergoing liposuction single, defined region.This clinical study enrolled 23 patients body mass index (BMI) <25 kg/m(2) who had localized anterior contour defect. Patients underwent standard...
OBJECTIVE: This study was undertaken to assess the acute safety and feasibility of rapidly inducing, maintaining, then reversing hypothermia using a novel heat transfer catheter closed-loop automatic feedback temperature control system overcome limitations imposed by current clinical practices used for perioperative cooling warming. METHODS Six swine (mean mass, 53.8 ± 3.6 kg) were studied. The placed in inferior vena cava via femoral vein. Hypothermia 32°C induced, maintained 6 hours,...
Our previous clinical study supported the concept that capsular contracture is associated with subclinical infection of silicone implants. If bacterial presence, indeed, contributes to contracture, then fibroblast behavior might be expected change in presence bacteria by-products. Therefore, possible alteration by products was undertaken using an vitro model cultured dermal fibroblasts. Coagulase-negative staphylococci from mammary and penile implants were isolated their phenotypic features...
Mild hypothermia has been shown to provide protective effects in patients with ischemia (e.g. acute stroke and heart attack), but traditional methods for inducing, maintaining, reversing are slow, difficult administer control, uncomfortable patients. An innovative method produces mild, wholebody (32 degrees C 34 C) by use of an endovascular heat exchanger placed into the inferior vena cava. A closed-loop system accurately changes core body temperature average cool-down rates 4.8 per hour,...
The antihypertensive effect of transdermal clonidine (TC) vs. oral propranolol (OP) was evaluated in 32 patients with mild essential hypertension (mean BP 150/95 mm Hg). protocol consisted a 4-week pretreatment washout period, 2- to 6-week titration, maintenance phase, and 1-week postwashout phase. control (diastolic less than 90 Hg) achieved 15 out 17 patients, 12 14 subjects. Comparable decreases systolic/diastolic were noted (-19/15 Hg for TC -24/13 OP). No rebound symptoms reported after...
Summary: The antihypertensive effect of transdermal clonidine (TC) vs. oral propranolol (OP) was evaluated in 32 patients with mild essential hypertension (mean BP 150/95 mm Hg). protocol consisted a 4-week pretreatment washout period, 2- to 6-week titration, maintenance phase, and 1-week postwashout phase. control (diastolic < 90 Hg) achieved 15 out 17 patients, 12 14 subjects. Comparable decreases systolic/diastolic were noted (−19/15 Hg for TC −24/13 OP). No rebound symptoms reported...
The antihypertensive effect of transdermal clonidine (TC) vs. oral propranolol (OP) was evaluated in 32 patients with mild essential hypertension (mean BP 150/95 mm Hg). protocol consisted a 4-week pretreatment washout period, 2- to 6-week titration, maintenance phase, and 1-week postwashout phase. control (diastolic < 90 Hg) achieved 15 out 17 patients, 12 14 subjects. Comparable decreases systolic/diastolic were noted (-19/15 Hg for TC -24/13 OP). No rebound symptoms reported after sudden...