Giovanni Scognamiglio
A5045342353- Estrogen and related hormone effects
- Nutrition, Genetics, and Disease
- Gene expression and cancer classification
- Genetic factors in colorectal cancer
- Cancer Risks and Factors
- Cancer Cells and Metastasis
- Cytokine Signaling Pathways and Interactions
- Radiomics and Machine Learning in Medical Imaging
- Bioinformatics and Genomic Networks
- Reproductive tract infections research
- Liver Disease Diagnosis and Treatment
- Diabetes Treatment and Management
- Ovarian function and disorders
- Diet and metabolism studies
- BRCA gene mutations in cancer
- Reproductive Biology and Fertility
- Ovarian cancer diagnosis and treatment
- Pelvic floor disorders treatments
- Urinary Tract Infections Management
- Bone and Joint Diseases
- Hemoglobin structure and function
- Peroxisome Proliferator-Activated Receptors
- Clusterin in disease pathology
- Lipid metabolism and disorders
- Metabolism, Diabetes, and Cancer
Ospedale Valduce
2023
University of Naples Federico II
1996
During the years 1991-1994, 97 anovulatory infertile women with polycystic ovarian syndrome (PCOS) were treated laparoscopic electrocautery of surface after they had failed to ovulate under stimulation. To assess endocrinological and clinical outcome in an attempt determine mechanism action, serum levels luteinizing hormone (LH), follicle-stimulating (FSH), androstenedione, testosterone dehydroepiandrosterone sulfate (DHEAS) determined before cautery. Fifty regularly cycling undergoing...
Abstract Purpose: In estrogen receptor–positive (ER+) breast cancer, single-nucleotide polymorphisms (SNP) in the aromatase gene might affect inhibitors (AI) metabolism and efficacy. Here, we assessed impact of SNP on prognosis toxicity patients receiving adjuvant letrozole. Experimental Design: We enrolled 886 postmenopausal study. They were treated with letrozole for 2 to 5 years after taking tamoxifen 6 years, continuing until they completed 10 therapy. Germline DNA was genotyped rs4646,...
<p>Figure S1: CONSORT diagram of all patients included from the GIM4 and GIM5 trials</p>
<p>Figure S2. Linkage disequilibrium plot (a) and haplotypes frequencies (b) of the four analyzed SNPs CYP19 in Caucasian population</p>
<p>Figure S4. Cumulative incidence of breast cancer metastasis and death in the GIM4 trial (a) GIM5 study (b).</p>
<p>Figure S4. Cumulative incidence of breast cancer metastasis and death in the GIM4 trial (a) GIM5 study (b).</p>
<p>Template to request patient-level data corresponding author</p>
<p>Figure S2. Linkage disequilibrium plot (a) and haplotypes frequencies (b) of the four analyzed SNPs CYP19 in Caucasian population</p>