Andrei Manea

ORCID: 0009-0002-0922-8565
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About
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Research Areas
  • Family Support in Illness
  • Cancer and Skin Lesions
  • Nonmelanoma Skin Cancer Studies
  • Personality Disorders and Psychopathology
  • Cancer survivorship and care
  • Personality Traits and Psychology
  • Intracranial Aneurysms: Treatment and Complications
  • Adipokines, Inflammation, and Metabolic Diseases
  • Hemophilia Treatment and Research
  • Bee Products Chemical Analysis
  • Diabetic Foot Ulcer Assessment and Management
  • Blood Coagulation and Thrombosis Mechanisms
  • Cardiac Arrest and Resuscitation
  • Polyomavirus and related diseases
  • Venous Thromboembolism Diagnosis and Management
  • Skin Protection and Aging
  • Calcium signaling and nucleotide metabolism
  • Cancer-related cognitive impairment studies
  • Electrospun Nanofibers in Biomedical Applications
  • Advancements in Transdermal Drug Delivery
  • Polysaccharides Composition and Applications
  • Photoacoustic and Ultrasonic Imaging
  • Ultrasound and Hyperthermia Applications
  • Inflammasome and immune disorders
  • MicroRNA in disease regulation

Spitalul Clinic Judetean de Urgenta Târgu Mureş
2024-2025

Universitatea de Medicină, Farmacie, Științe și Tehnologie „George Emil Palade” din Târgu Mureș
2023-2025

Spitalul Clinic Judetean Mures
2024

Background/Objectives: Ventilator-associated pneumonia (VAP) is the most common nosocomial infection encountered in intensive care unit (ICU) and associated with prolonged hospitalization increased mortality. We evaluated causative pathogens involved their resistance to major classes of antibiotics patients VAP assessed differences between without coronavirus disease 2019 (COVID-19). Materials Methods: This study was a single-center, cross-sectional, retrospective analysis involving 122 who...

10.3390/antibiotics14010028 article EN cc-by Antibiotics 2025-01-03

Basal cell carcinoma (BCC) and cutaneous squamous (cSCC) are the most frequently occurring non-melanocytic skin cancers. The objective of our study is to present pathophysiology BCC cSCC its direct relationship with histopathological diagnostics differential these types cancer, based on morphological characteristics, immunohistochemical profile, genetic alterations. qualitative was emphasizing characteristics immunohistochemistry profiles tissue samples from Clinical Pathology Department...

10.3390/ijms25042220 article EN International Journal of Molecular Sciences 2024-02-13

Persistent trigeminal artery disease is one of the most common types persistent carotid-vertebrobasilar anastomoses. Usually, it unilateral, and can be discovered with a magnetic resonance angiography (MRA), computed tomography (angioCT), or classic exam. It associated non-specific symptoms, such as headaches, more specific ones, III VI nerve palsy neuralgia, but time goes undetected, being an incidental finding not causing any symptoms. On MRA angioCT, has characteristic "tau" sign. We...

10.7759/cureus.61060 article EN Cureus 2024-05-25

Background and aim Psychiatric pathology does not always start on its own but may be conditioned or triggered by a comorbidity with high impact the human psyche. When there are comorbidities, psychiatric can occur due to diagnostic burden. Our study aims find out if is correlation between diagnosis of breast cancer severity, symptoms such as depressive mood, atypical anxiety, even autolytic ideation that directly influence quality life patients. Materials methods The prospective,...

10.7759/cureus.65870 article EN Cureus 2024-07-31

Individual personality refers to the Ego and interpersonal sector. The corresponds consciousness self-esteem, including capacities for emotional self-regulation, self-control, self-evaluation, self-direction in relation personal goals. When neoplastic psychiatric diseases coexist, a patient's quality of life is significantly impacted. While there are somatic differences disease progression, how illness perceived mainly experienced depends on traits. In this study, we administered DECAS...

10.25122/jml-2024-0302 article EN Journal of Medicine and Life 2024-06-01

Although thrombotic events are uncommon in young individuals, patients with genetic mutations coagulation factors may develop extensive multisite thrombosis. We present the case of a 26-year-old patient, smoker for nine years, who was admitted to hospital complaining right thigh pain swelling, flank abdominal pain, dyspnea, and hemoptysis. A medical history provided by patient indicated that one month prior presentation, an accidental fall had resulted multiple rib fractures, bilateral...

10.7759/cureus.72425 article EN Cureus 2024-10-26

The search for novel ways of providing treatment also targets the development formulations used in drug delivery. Among important characteristics pharmaceutical gels are their ability to penetrate membranes, capability offer rapid response, and capacity avoid hepatic metabolization route followed by many drugs. Bigels combine advantages both hydrogels oleogels, creating a biphasic system that might improve solubility amiodarone water, which is otherwise poorly soluble. This study aimed...

10.3390/ph17111511 article EN cc-by Pharmaceuticals 2024-11-09

Abstract Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main source(s): UEFISCDI Background MicroRNAs are important biomarkers and potential therapeutic targets in atherosclerosis. MiR-155-5p amplifies inflammation atherosclerosis by targeting negative regulators NF-kB signaling pathway. Inhibition pro-atherogenic miRNAs or mimicking the function selected anti-atherogenic have emerged as prospective oligonucleotide-base interventions order to...

10.1093/cvr/cvac066.197 article EN Cardiovascular Research 2022-06-01

Abstract Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main source(s): UEFISCDI Background Diabetic kidney disease (DKD) is arguably the major disabling and life-threatening microvascular-related disorder associated with both type I II diabetes. Inflammation glomerular capillary system progressive accumulation extracellular proteins are important culprit mechanisms leading to glomerulosclerosis ultimately renal failure in end-stage DKD....

10.1093/cvr/cvac066.225 article EN Cardiovascular Research 2022-06-01

Abstract Objective: Cutaneous squamous cell carcinoma (cSCC) is a skin malignancy that one of the non-melanocytic cancers (NMSCs). The objective our study was to highlight epidemiological and histological characteristics cSCC diagnosed in clinical county hospital. Methods A retrospective cross-sectional performed histopathologically cases from Pathology Department Mures Clinical County Hospital, Târgu Mureș, Romania. We included 96 were between January 1, 2017, December 31, 2020. Results: Of...

10.2478/amma-2023-0043 article EN cc-by Acta Marisiensis. Seria Medica 2023-12-01
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