A5103194905- Neonatal and fetal brain pathology
- Neonatal Respiratory Health Research
- Pregnancy and preeclampsia studies
- Birth, Development, and Health
- Prenatal Screening and Diagnostics
- Assisted Reproductive Technology and Twin Pregnancy
- Gestational Diabetes Research and Management
- Infant Development and Preterm Care
- Congenital Heart Disease Studies
- Fetal and Pediatric Neurological Disorders
- Congenital Diaphragmatic Hernia Studies
- Emergency and Acute Care Studies
- Neuroscience of respiration and sleep
- Neonatal Health and Biochemistry
- Cardiac Arrhythmias and Treatments
- Maternal and Perinatal Health Interventions
- Cardiovascular Issues in Pregnancy
- Congenital Anomalies and Fetal Surgery
- Parvovirus B19 Infection Studies
- Phonocardiography and Auscultation Techniques
- Maternal Mental Health During Pregnancy and Postpartum
- Preterm Birth and Chorioamnionitis
- Infant Nutrition and Health
- Cardiac Arrest and Resuscitation
- Urological Disorders and Treatments
Stichting Epilepsie Instellingen Nederland
2024
University Medical Center Utrecht
2013-2023
Utrecht University
2009-2021
International Federation of Gynaecology and Obstetrics
2018-2020
Wilhelmina Children's Hospital
2005-2019
John Wiley & Sons (United Kingdom)
2019
Hudson Institute
2019
Hospital de São João
2017
University Medical Center Groningen
2009-2015
University of Groningen
1985-2015
ABSTRACT Objectives Few data exist for counseling and perinatal management of women after an antenatal diagnosis early‐onset fetal growth restriction. Yet, the consequences preterm delivery its attendant morbidity both mother baby are far reaching. The objective this study was to describe mortality following restriction based on time delivery. Methods We report cohort outcomes a prospective multicenter randomized (Trial Randomized Umbilical Fetal Flow in Europe ( TRUFFLE )) performed 20...
Hack, K.E.A.; Derks, J.B.; Elias, S.G.; Franx, A.; Roos, E.J.; Voerman, S.K.; Bode, C.L.; Koopman-Esseboom, C.; Visser, G.H.A. Author Information
<b>Objective</b> To evaluate the incidence of serious maternal complications after use various tocolytic drugs for treatment preterm labour in routine clinical situations. <b>Design</b> Prospective cohort study. <b>Setting</b> 28 hospitals Netherlands and Belgium. <b>Participants</b> 1920 consecutive women treated with tocolytics threatened labour. <b>Main outcome measures</b> Maternal adverse events (those suspected being causally related to were considered drug reactions) leading cessation...
In Brief OBJECTIVE: To estimate the effectiveness of intrapartum fetal monitoring by cardiotocography plus ST analysis using a strict protocol for performance blood sampling. METHODS: We performed multicenter randomized trial among laboring women with high-risk singleton pregnancy in cephalic presentation beyond 36 weeks gestation. Participants were assigned to (index) or only (control). Primary outcome was metabolic acidosis, defined as an umbilical cord artery pH below 7.05 combined base...
The use of fetal growth charts assumes that the optimal size at birth is 50(th) birth-weight centile, but interaction between maternal constraints on and risks associated with small large may indicate this assumption not valid for perinatal mortality rates. objective study was to investigate distribution timing (antenatal, intrapartum or neonatal) morbidity in relation weight gestational age delivery.Data from over 1 million births occurring 28-43 weeks' gestation singleton pregnancies...
Objectives To compare the effects of maternal betamethasone and dexamethasone administration on fetal behaviour heart rate variation. Design Aprospective randomised study 60 women at increased risk preterm delivery. Outcome measures Fetal its variation, incidence body breathing movements. Setting Obstetric unit, University Hospital, Utrecht, The Netherlands. Results Following (day 2), variation was reduced by 19% movements 49% 85%, respectively. After treatment there a significant increase...
ABSTRACT Objective To examine prospectively the effects of maternal betamethasone administration on fetal heart rate variation, body, breathing and eye movements rest‐activity cycle. Design Thirty‐one women 38 occasions were at risk premature delivery received two doses 24 h apart. Gestational age ranged between 26 32 weeks. Fetal was monitored each five successive days (0–4) recorded 0, 2 4. Results Compared with control day before steroid (day 0), both long term short variation reduced 3 (...
In Brief OBJECTIVE: To study perinatal mortality and neonatal morbidity in a large cohort of monoamniotic twin pregnancies with special emphasis to the gestational age-specific mortality. METHODS: The included delivered 10 centers Netherlands between January 2000 December 2007. RESULTS: A total 98 were included. rate (20 weeks gestation through 28 days life) was 19%; after exclusion fetuses lethal anomalies, 17%. After 32 gestation, only two complicated by (4%). incidence twin–twin...
To identify short-term factors influencing psychological outcome of termination pregnancy for fetal anomaly, in order to define those patients most vulnerable psychopathology.A prospective cohort 217 women and 169 men completed standardized questionnaires 4 months after termination. Psychological adjustment was measured by the Inventory Complicated Grief (ICG), Impact Event Scale (IES), Edinburgh Postnatal Depression (EPDS), Symptom Checklist-90 (SCL-90).Women showed high levels...
The unstressed antepartum cardiotocogram (CTG) is principally judged by two aspects: baseline irregularity, and reaction to Braxton Hicks contractions fetal movements. A classification into normal, sub-optimal, decelerative, terminal CTG was devised. ominous significance of the confirmed in 26 patients; nine fetuses died utero other 17 were delivered elective Caesarean section; only one newborn neither small-for-dates nor acidaemic. three categories evaluated 428 patients whom labour...
To establish reference curves for size and volume of the fetal kidney, renal pelvis adrenal gland, as measured using ultrasound from 15(th) week gestation.This was a prospective, longitudinal study 96 fetuses in low-risk singleton pregnancies, which we performed serial examinations at 4-week intervals. The length anteroposterior transverse diameters both kidneys, pelvises glands were three times each examination, with average being used further analysis. Reference charts constructed...
Cardiotocography (CTG) has a high sensitivity but only limited specificity in predicting fetal hypoxia/acidosis [1]. In other words, normal CTG is reassuring regarding the state of oxygenation as generally restricted to cases with suspicious or pathological patterns (see definitions given chapter [1]). However, large number fetuses latter will not have clinically important [2,3]. To reduce such false positive and unnecessary medical interventions, adjunctive technologies been proposed...