Xianghui Zhang

ORCID: 0009-0002-3075-4260
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About
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Research Areas
  • Biochemical and Structural Characterization
  • Neuropeptides and Animal Physiology
  • Antibiotic Resistance in Bacteria
  • Metal-Catalyzed Oxygenation Mechanisms
  • Pain Mechanisms and Treatments
  • Antimicrobial Resistance in Staphylococcus
  • Covalent Organic Framework Applications
  • Bacterial Genetics and Biotechnology
  • Thermoregulation and physiological responses
  • Bacteriophages and microbial interactions
  • Microbial bioremediation and biosurfactants
  • Conducting polymers and applications
  • Advanced Nanomaterials in Catalysis
  • Neonatal Health and Biochemistry
  • Textile materials and evaluations
  • Antimicrobial Peptides and Activities
  • Bacterial biofilms and quorum sensing
  • Carbon and Quantum Dots Applications
  • Heme Oxygenase-1 and Carbon Monoxide
  • Ergonomics and Musculoskeletal Disorders
  • Porphyrin and Phthalocyanine Chemistry
  • Supercapacitor Materials and Fabrication
  • Nanocluster Synthesis and Applications
  • Chemical Analysis and Environmental Impact
  • Pesticide and Herbicide Environmental Studies

Shandong University
2023-2024

Qufu Normal University
2019-2022

Lanzhou University
2020

Donghua University
2009

Quorum sensing inhibitors (QSIs) are a class of compounds that can reduce the pathogenicity bacteria without affecting bacterial growth. In this study, we designed and synthesized four series 4-fluorophenyl-5-methylene-2(5H)-furanone derivatives evaluated their QSI activities. Among them, compound 23e not only showed excellent inhibitory activity against various virulence factors but also significantly enhanced antibiotics ciprofloxacin clarithromycin two strains Pseudomonas aeruginosa in...

10.1021/acs.jmedchem.2c01866 article EN Journal of Medicinal Chemistry 2023-06-13

The development of nanocluster (NC)-based luminescent functional materials has gained tremendous attention recently owing to their unique optical properties. Herein, we studied the coassembly behavior AuNCs modified using 6-propyl-2-thiouracil (PRT-AuNCs) with trimesic acid (TA). Microrods were formed through coassembly, accompanied enhanced photoluminescence emission. intermolecular hydrogen bonding and π–π stacking between TA PRT ligands verified be main driving forces for formation...

10.1021/acsanm.2c02496 article EN ACS Applied Nano Materials 2022-06-27

The H2O2-dependent degradation of haloindole catalyzed by the dehaloperoxidase (DHP) from Amphitrite ornate has been reported to employ peroxygenase mechanism, and two oxidized products 5-halo-2-oxindole 5-halo-3-oxindole have a similar amount. According previous experimental study, compound I (Cpd I) was suggested be responsible for triggering reaction, reaction may undergo three possible intermediates; however, details are still unclear. To clarify mechanism DHP, computational model...

10.1021/acs.inorgchem.3c01425 article EN Inorganic Chemistry 2023-08-10

The heme-containing chlorite dismutases catalyze the rapid and efficient decomposition of (ClO

10.1021/acs.inorgchem.4c00126 article EN Inorganic Chemistry 2024-04-04

The AAD-1 enzyme belongs to the Fe(II) and α-ketoglutarate (Fe/αKG)-dependent nonheme aryloxyalkanoate dioxygenase family (AADs), which catalyzes breakdown of 2,4-dichlorophenoxyacetic acid (2,4-D, an active ingredient thousands commercial herbicides) by using highly Fe(IV)═O complex. Multiple species bacteria degrade 2,4-D via a pathway initiated AADs; however, detail how they promote cleavage ether C–O bond generate 2,4-dichlorophenol (2,4-DCP) glyoxylate is still unclear, prerequisite for...

10.1021/acs.jcim.2c01381 article EN Journal of Chemical Information and Modeling 2023-04-26
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