- Biochemical Analysis and Sensing Techniques
- Plant Parasitism and Resistance
- Natural Antidiabetic Agents Studies
- Plant Stress Responses and Tolerance
- Fungal Biology and Applications
- Analytical Chemistry and Chromatography
- Biochemical and biochemical processes
- Molecular spectroscopy and chirality
- Pancreatic function and diabetes
- Alcoholism and Thiamine Deficiency
- Natural Compound Pharmacology Studies
- Mycorrhizal Fungi and Plant Interactions
- Plant Molecular Biology Research
- Phytochemistry and Biological Activities
- Polyamine Metabolism and Applications
Technical University of Munich
2018-2025
Leibniz-Institute for Food Systems Biology at the Technical University of Munich
2018-2023
Summary Arbuscular mycorrhiza (AM) improves mineral nutrient supply, stress tolerance, and growth of host plants through re‐programing plant physiology. We investigated the effect AM on root secondary metabolome model legume Lotus japonicus using untargeted metabolomics. Acetonitrile extracts control roots were analysed ultra‐high‐performance liquid chromatography‐electrospray ionization‐ion mobility‐time‐of‐flight‐mass spectrometry (UPLC‐ESI‐IM‐ToF‐MS). characterized AM‐regulated...
Bioactive plant compounds and extracts are of special interest for the development pharmaceuticals. Here, we describe screening more than 1100 aqueous synthetic reference their ability to stimulate or inhibit insulin secretion. To quantify secretion in living MIN6 β cells, an insulin–Gaussia luciferase (Ins-GLuc) biosensor was used. Positive hits included from Quillaja saponaria, Anagallis arvensis, Sapindus mukorossi, Gleditsia sinensis Albizia julibrissin, which were identified as...
Increasing the thiamine concentration in a respective process flavor yields product with significant higher kokumi activity. S-plot analysis of mass spectrometric data revealed beside itself, 4-methyl-5-thiazoleethanol, (S)-((4-amino-2-methylpyrimidin-5-yl)methyl)-l-cysteine, N-((4-amino-2-methylpyrimidin-5-yl)methyl)formamide, 3-(((4-amino-2-methylpyrimidin-5-yl)methyl)thio)-5-hydroxypentan-2-one, and 2-methyl-5-(((2-methylfuran-3-yl)thio)methyl)pyrimidin-4-amine as marker molecules for...
Thirty-four reference compounds from G. buchananii were analyzed by means of UPLC-ESI-IMS-TOF-MS to build a database consisting retention time, accurate m/ z precursors and fragment ions, rotationally averaged collision cross-sectional area (CCS). The CCS value six selected in bark extract different concentrations solvent systems showed excellent intra- interday precision (RSD ≤ 0.9%). established was applied on organs as well kola, mangostana, cambogia enabling fast reliable identification...
To obtain high-kokumi-active building blocks, which can be used to produce savory process flavors, it is essential a better understanding on the formation rate of kokumi-active compounds, such as 3-(((4-amino-2-methylpyrimidin-5-yl)methyl)thio)-5-hydroxypentan-2-one or 2-methyl-5-(((2-methylfuran-3-yl)thio)methyl)pyrimidin-4-amine. The present work showed quantitative studies in several model reaction systems recently discovered thiamine derivates. It was possible show that conversion...
Abstract An arbuscular mycorrhiza symbiosis, which is established by 80% of all vascular plants and Glomeromycota fungi, can boost the growth, stress tolerance, yield agricultural crop increasing mineral supply host plant [1]. Mineral nutrients absorbed fungus are exchanged for photoassimilates from via highly branched fungal structures called arbuscules formed within root cortex cells [2]. The process arbuscule formation degradation dynamic accompanied considerable cell reprogramming [3],...