A5035485360- Regulation of Appetite and Obesity
- Eating Disorders and Behaviors
- Neuropeptides and Animal Physiology
- Biochemical Analysis and Sensing Techniques
- Diet and metabolism studies
- Public Health and Nutrition
- Seaweed-derived Bioactive Compounds
- Neurotransmitter Receptor Influence on Behavior
- Adipose Tissue and Metabolism
- Nutrition, Genetics, and Disease
- Food Industry and Aquatic Biology
- Obesity, Physical Activity, Diet
- Fatty Acid Research and Health
- Obsessive-Compulsive Spectrum Disorders
- Cholinesterase and Neurodegenerative Diseases
- Pharmacology and Obesity Treatment
- Adipokines, Inflammation, and Metabolic Diseases
- Evolutionary Psychology and Human Behavior
- Child Nutrition and Feeding Issues
- Bone health and osteoporosis research
- Stress Responses and Cortisol
- Pancreatic function and diabetes
- Cystic Fibrosis Research Advances
- Dementia and Cognitive Impairment Research
- Birth, Development, and Health
East Suffolk and North Essex NHS Foundation Trust
2023
Howard University
2023
University of Alabama at Birmingham
2001-2004
University of Cincinnati Medical Center
1999-2001
The University of Texas at El Paso
1991-1999
University of California, Davis
1999
Veterans Health Administration
1999
Emory University
1999
University of Cincinnati
1999
Autonomous University of Chihuahua
1999
Objective To test the hypothesis that experience with food restriction produces persistent binge eating. The Minnesota semistarvation experiment and studies of prisoners-of-war show chronic dramatic changes in eating behavior (including eating) endure decades after has ceased. Bulimia nervosa patients who restrict also binge. Restriction may be a risk factor etiology bulimia. Method: Animals were subjected to four different patterns 12-week restriction-refeeding cycles. rats either...
Summary: The purpose of the present study was to evaluate methanesulfonyl fluoride (MSF), a very long-acting CNS-selective acetylcholinesterase (AChE) inhibitor, as palliative treatment for senile dementia Alzheimer type (SDAT). In experiment I, MSF (0.03-0.18 mg/ kg) administered orally 10 normal volunteers measure toxicity and establish dose/ response function in erythrocyte AChE. produced dose-response % inhibition=(40)(Logl0[MSF kg] + 51.7) with no at these doses. Experiment II 16-week...
Several lines of evidence substantiate the important role central nervous system melanocortin 3- and 4-receptor (MC3/4-R) in control food intake energy balance. Agouti-related peptide (AgRP), an endogenous antagonist these receptors, produces a robust unique pattern increased that lasts up to 7 days after single injection. Little is known about brain regions may mediate this powerful effect AgRP on intake. To end we compared c-Fos-like immunoreactivity (c-FLI) several sites rats injected...
Leptin (OB protein) is an important signal in the regulation of energy balance.Leptin levels correlate with adiposity, but also decrease acutely caloric restriction and increase refeeding.The brain established critical site leptin function, yet little known about concentrations central nervous system relative to plasma levels, psychiatric diagnoses, other endocrine parameters.Therefore, using a novel ultrasensitive assay, we explored relationships human cerebrospinal fluid (CSF) body mass...
Binge eating is a consequence of semistarvation in victims war and famine volunteers rare experiments. These behaviors include bizarre mixing ingredients adulteration food; inappropriate, soiled, or discarded secrecy; deception; defensiveness. Drastic measures to resist overeating persist long after the experience, even when food plentiful. eating, central feature bulimia sometimes anorexia nervosa, prevalent modern society, but occurrence frequency semistarvation-related have not been well...
Objective To test the hypothesis that experience with food restriction produces persistent binge eating. The Minnesota semistarvation experiment and studies of prisoners-of-war show chronic dramatic changes in eating behavior (including eating) endure decades after has ceased. Bulimia nervosa patients who restrict also binge. Restriction may be a risk factor etiology bulimia. Method: Animals were subjected to four different patterns 12-week restriction-refeeding cycles. rats either...
Commensurate with the last decades increasing prevalence of obesity is number breakthroughs in physiology energy regulation. Primary these role played by CNS melanocortin 3 and 4 receptors (MC3 / 4R). The MC3 ligand, alpha-melanocyte stimulating hormone, a primary anti-obesity target due to its anorectic catabolic actions. A level complexity introduced agouti related peptide, an endogenous antagonist at 4R that exerts orexigenic anabolic functions. Here we evidence utility MC system treat...