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Valeriy Vyaltsev

ORCID: 0009-0002-4882-1871
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A5094020489
Research Areas
  • RNA and protein synthesis mechanisms
  • RNA modifications and cancer
  • RNA Research and Splicing

Lomonosov Moscow State University
 2024

 Ribonanza: deep learning of RNA structure through dual crowdsourcing
OPENALEX - Publications 
Shujun He Rui Huang Jill Townley Rachael C. Kretsch Thomas G. Karagianes and 30 more David Cox H. Blair Dmitry Penzar Valeriy Vyaltsev Elizaveta Aristova Arsenii Zinkevich A. E. Bakulin Hoyeol Sohn Daniel Krstevski Takaaki Fukui Fumiya Tatematsu Yusuke Uchida Donghoon Jang Jun Seong Lee Roger Shieh Tom Ma E.S. Martynov Maxim V. Shugaev Habib S.T. Bukhari Kazuki Fujikawa Kazuki Onodera Christof Henkel Shlomo Ron Jonathan Romano John J. Nicol Grace Nye Yuan Wu Christian A. Choe Walter Reade Rhiju Das

Prediction of RNA structure from sequence remains an unsolved problem, and progress has been slowed by a paucity experimental data. Here, we present Ribonanza, dataset chemical mapping measurements on two million diverse sequences collected through Eterna other crowdsourced initiatives. Ribonanza enabled solicitation, training, prospective evaluation deep neural networks Kaggle challenge, followed distillation into single, self-contained model called RibonanzaNet. When fine tuned auxiliary...

10.1101/2024.02.24.581671 preprint EN cc-by bioRxiv (Cold Spring Harbor Laboratory) 2024-02-27
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