Nan Chen

ORCID: 0009-0002-7197-8164
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About
Contact & Profiles
Research Areas
  • Gastric Cancer Management and Outcomes
  • Colorectal Cancer Treatments and Studies
  • Colorectal and Anal Carcinomas
  • Genetic factors in colorectal cancer

Queen's University
2024

Abstract Purpose: Sidedness is prognostic and predictive of anti-EGFR efficacy in metastatic colorectal cancer (mCRC). Transverse colon has been historically excluded from several analyses sidedness the optimal division between left- right-sided unclear. We investigated transverse primary tumor location as a biomarker mCRC. Experimental Design: Pooled analysis CCTG/AGITG CO.17 CO.20 trials cetuximab chemotherapy-refractory Outcomes patients with RAS/BRAF wild-type (WT) mCRC KRAS WT were...

10.1158/1078-0432.ccr-23-3275 article EN cc-by-nc-nd Clinical Cancer Research 2024-01-03

<div>AbstractPurpose:<p>Sidedness is prognostic and predictive of anti-EGFR efficacy in metastatic colorectal cancer (mCRC). Transverse colon has been historically excluded from several analyses sidedness the optimal division between left- right-sided unclear. We investigated transverse primary tumor location as a biomarker mCRC.</p>Experimental Design:<p>Pooled analysis CCTG/AGITG CO.17 CO.20 trials cetuximab chemotherapy-refractory mCRC. Outcomes patients with...

10.1158/1078-0432.c.7122875.v1 preprint EN 2024-03-15

<div>AbstractPurpose:<p>Sidedness is prognostic and predictive of anti-EGFR efficacy in metastatic colorectal cancer (mCRC). Transverse colon has been historically excluded from several analyses sidedness the optimal division between left- right-sided unclear. We investigated transverse primary tumor location as a biomarker mCRC.</p>Experimental Design:<p>Pooled analysis CCTG/AGITG CO.17 CO.20 trials cetuximab chemotherapy-refractory mCRC. Outcomes patients with...

10.1158/1078-0432.c.7122875 preprint EN 2024-03-15
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