A5040285891- Cancer, Hypoxia, and Metabolism
- Renal cell carcinoma treatment
- Gestational Diabetes Research and Management
- Pregnancy and preeclampsia studies
- Colorectal and Anal Carcinomas
- Diagnosis and treatment of tuberculosis
- Gastric Cancer Management and Outcomes
- Infectious Diseases and Tuberculosis
- Ferroptosis and cancer prognosis
- Pancreatic and Hepatic Oncology Research
- Tuberculosis Research and Epidemiology
- Colorectal Cancer Surgical Treatments
- Bariatric Surgery and Outcomes
Thai Binh University of Medicine and Pharmacy
2024
Calithera (United States)
2018-2019
HCMC Hospital of Dermato Venereology
2018
TPS4601 Background: Glutamine utilization is a metabolic pathway upregulated in renal cell carcinoma (RCC) and important for RCC tumor proliferation survival. CB-839 first-in-class, potent, oral inhibitor of the mitochondrial enzyme glutaminase (GLS) that controls critical step glutamine. In preclinical models, demonstrated synergistic anti-tumor activity when combined with cabozantinib, VEGFR/MET inhibitor. A phase 1 study cohort plus cabozantinib as 2L+ therapy showed encouraging safety...
TPS682 Background: Glutamine metabolism is upregulated in renal cell carcinoma (RCC) and important for RCC tumor proliferation survival. CB-839 a first-in-clinic, potent, oral inhibitor of the mitochondrial enzyme glutaminase (GLS), which controls critical step glutamine. demonstrated synergistic anti-tumor activity when combined with cabozantinib, VEGFR2/MET/AXL inhibitor, preclinical models. In phase 1 study cohort, plus cabozantinib as 2L+ therapy showed encouraging safety efficacy...
<sec> <title>BACKGROUND</title> Gestational diabetes mellitus (GDM) is the most common metabolic disorder in pregnancy, and has become an increasing major global public health concern because of its adverse implications for mother fetal health. </sec> <title>OBJECTIVE</title> The objective this study was to determine prevalence risk factors GDM rural areas Vietnam. <title>METHODS</title> This cross-sectional conducted among 1003 pregnant women, aged ≥18 years Northern identified as impaired...
Abstract Objectives To investigate the differences in clinical, radiological and laboratory parameters between elderly young patients with newly diagnosed smear‐positive pulmonary tuberculosis Vietnam. Methods This retrospective analysis included all hospitalised acid‐fast bacilli‐positive smear. Clinical symptoms, results chest X‐ray findings were collected using a standardised questionnaire. Elderly was defined as those aged 65 years older. Results A total of 183 new this study, mean age...