A5100337709- Graphene and Nanomaterials Applications
- Nanoplatforms for cancer theranostics
- Nanoparticle-Based Drug Delivery
- Bone Tissue Engineering Materials
- Carbon and Quantum Dots Applications
- Nanocluster Synthesis and Applications
- Advanced biosensing and bioanalysis techniques
- Alzheimer's disease research and treatments
- Graphene research and applications
- Advanced Sensor and Energy Harvesting Materials
- Cholinesterase and Neurodegenerative Diseases
- Boron Compounds in Chemistry
- Cancer, Hypoxia, and Metabolism
- Membrane Separation Technologies
- Glioma Diagnosis and Treatment
- Electrochemical sensors and biosensors
- Luminescence and Fluorescent Materials
- Advanced Drug Delivery Systems
- Supramolecular Self-Assembly in Materials
- Cancer-related molecular mechanisms research
- Advanced Nanomaterials in Catalysis
- Carbon Nanotubes in Composites
- Orthopaedic implants and arthroplasty
East China Normal University
2025
Bengbu Medical College
2023
Chinese Academy of Medical Sciences & Peking Union Medical College
2022
Jiangxi University of Science and Technology
2021
Ministry of Agriculture and Rural Affairs
2019
Tea Research Institute
2019
Chinese Academy of Agricultural Sciences
2019
Sichuan University
2018
Fuzhou University
2016
Center for NanoScience
2015
Abstract Graphene oxide (GO) is utilized as the modulator to tune formation and development of amyloid fibrils (Aβ 33–42 ). Atomic force microscopy temporal evolution measurements reveal that initial binding between peptide monomer large available surface GO sheets can redirect assembly pathway beta. The results support possibility develop graphene‐based materials inhibit amyloidosis.
The current cancer therapies in clinical practice demonstrate the need for improvements such as improving efficiency and reducing severe side effects. Herein, we integrated targeted chemotherapy photothermal therapy a multifunctional drug-delivery platform. targeting DNA aptamer (Apt)-modified graphene oxide-gold nanoparticle (GO-AuNP) composites were successfully synthesized. doxorubicin (DOX)-loaded GO-AuNP-Apt system showed heat-stimulative sustained release characteristics. In vitro cell...
Poly(<sc>l</sc>-lactide) (PLLA) is a promising bone repair material owing to its good biocompatibility and natural degradability, but lack of bioactivity insufficient mechanical property restrict further application.
A novel and convenient method to synthesize the nanocomposites combining graphene oxides (GO) with gold nanoparticles (AuNPs) is reported their applications modulate amyloid peptide aggregation are demonstrated. The produced by pulsed laser ablation (PLA) in water show good biocompatibility solubility. reduced of peptides confirmed Thioflavin T fluorescence atomic force microscopy. cell viability experiments reveals that presence can significantly reduce cytotoxicity peptides. Furthermore,...
Glioblastoma multiforme (GBM) is a highly aggressive and lethal brain tumor, with poor patient prognosis median overall survival of only 10 months despite the current Stupp protocol treatment, due to its high aggressiveness recurrence rate. This study investigated role IGF2BP1 gene in mesenchymal glioblastoma (GBM), revealing that upregulated tumor tissues compared adjacent normal positively correlates MYC expression prognosis. Immune infiltration analysis showed associated specific immune...
Pd‐based intracellular catalysis has attracted increasing interest in modulating biological processes or disease treatment. The unsatisfactory catalytic efficiency arising from limited active sites and poor water solubility of palladium nanoparticles (Pd NPs) their “always on” activities pose, however, significant limitations. Herein, we develop a high‐performance nanocomposite based on ultrafine Pd NPs confined within molecular cages, incorporated with glucose oxidase (GOx) AS1411...
Pd‐based intracellular catalysis has attracted increasing interest in modulating biological processes or disease treatment. The unsatisfactory catalytic efficiency arising from limited active sites and poor water solubility of palladium nanoparticles (Pd NPs) their “always on” activities pose, however, significant limitations. Herein, we develop a high‐performance nanocomposite based on ultrafine Pd NPs confined within molecular cages, incorporated with glucose oxidase (GOx) AS1411...
Abstract Malignant glioma has extremely poor prognosis despite combination treatments with surgery, radiation, and chemotherapy. Dendritic cell (DC)-based immunotherapy may potentially serve as an adjuvant treatment of glioma, but its efficacy generally needs further improvement. Here we explored whether graphene oxide (GO) nanosheets could modulate the DC-mediated anti-glioma immune response in vitro , using T98G human line study model. Pulsing DCs a peptide antigen (Ag) generated limited...
Chitosan-reduced graphene oxide composites with 3D structures (3D CS-rGO) were prepared via a facile solvothermal synthetic strategy. The reduction of GO and crosslinking rGO nanosheets CS into achieved simultaneously in one step. resulting CS-rGO composite achieves high adsorption capacities catechins, caffeine pigments from tea acetonitrile extraction, especially for which is 10 times higher than that (179.3 mg g-1vs. 18.7 g-1). exhibits the best removal efficiency matrix interference...
Graphite carbon nitride (g-C 3 N[Formula: see text] polymer with two-dimensional planar structure is a new star in nanodrug delivery systems recent years because it shows characteristics of low cost, nontoxicity, biocompatibility and easy functionalization. However, conventional g-C N 4 bulk, macro size, small specific surface area poor water solubility. To improve this, most works are always confined to physical ultrasound, oxidative peeling or template-strategy, which have the...