- Laser-Ablation Synthesis of Nanoparticles
- Craniofacial Disorders and Treatments
- Brain Metastases and Treatment
- Traumatic Brain Injury and Neurovascular Disturbances
- Hedgehog Signaling Pathway Studies
- Glioma Diagnosis and Treatment
- Hearing Loss and Rehabilitation
- Acute Ischemic Stroke Management
- Facial Trauma and Fracture Management
- Conducting polymers and applications
- Bone Tissue Engineering Materials
- Gold and Silver Nanoparticles Synthesis and Applications
- Meningioma and schwannoma management
- Electrospun Nanofibers in Biomedical Applications
- Nonlinear Optical Materials Studies
- Tissue Engineering and Regenerative Medicine
- Hearing, Cochlea, Tinnitus, Genetics
- Electrodeposition and Electroless Coatings
- Diamond and Carbon-based Materials Research
- Nanoparticles: synthesis and applications
- Bone and Joint Diseases
- Congenital limb and hand anomalies
- Medical and Biological Ozone Research
- Cleft Lip and Palate Research
Jena University Hospital
2024-2025
Friedrich Schiller University Jena
2024-2025
Laser Zentrum Hannover
2012-2014
University of Duisburg-Essen
2014
Chemical syntheses of homogenous solid solution alloy nanoparticles noble metals require high temperature above 100 °C. Beside this, aqueous co-reduction methods lead to phase separation. In contrast, pulsed laser ablation in liquid (PLAL) allows synthesis with totally homogeneous ultrastructure media at room without reducing agents or organic ligands. However, date, the dominant formation process during PLAL is not fully understood. Based on model Ag-Au alloy, we elucidate that underlying...
Although silver nanoparticles (AgNPs) are widely used as ion-releasing antimicrobial additives in medical devices, recent reports indicate the suppression of effectiveness presence blood serum proteins. Bovine albumin (BSA) is known to bind and ions, so that proteins may change antibacterial or cytotoxic properties AgNPs even when they embedded a solid agar hydrogel matrix. We produced ligand-free by laser ablation water resulting aqueous mass concentrations 0.5 7.1%. The were immersed into...
Importance Variations in perioperative dexamethasone dosing are common brain metastasis resection, but their impact on patient outcomes remains unclear. Objective To evaluate the association between and outcomes, focusing overall survival (OS) progression-free (PFS). Design, Setting, Participants This retrospective multicenter comparative effectiveness study used data collected from January 2010 to December 2023. Patients with symptomatic metastases undergoing primary surgical resection at 7...
Abstract To improve the electrode–nerve interface of cochlear implants (CI), role poly(L‐lactide) (PLLA) and poly(4‐hydroxybutyrate) (P(4HB)) as potential coating matrices for CI was assessed both in vitro vivo terms degradation behavior effects on spiral ganglion neurons, main target electrical stimulation with a CI. Growth rates fibroblasts polymers were investigated direct‐contact test freshly isolated cells (SGC) performed. In addition, polymer inside inner ear evaluated . The by use...
Autologous cells can be used for a bioactivation of osteoimplants to enhance osseointegration. In this regard, adipose derived stem (ASCs) offer interesting perspectives in implantology because they are fast and easy isolate. However, not all materials licensed bone implants equally suited cell adhesion. Surface modifications under investigation promote cytocompatibility growth. The presented study focused on influences Nitinol-nanoparticle coating ASCs. Possible toxic effects as well the...
Nanostructures entail a high potential for improving implant surfaces, instance, in stent applications. The electrophoretic deposition of laser-generated colloidal nanoparticles is an appropriate tool creating large-area nanostructures on surfaces. Until now, the bonding and characteristics interface between deposited substrate surface has not been known. It investigated using X-ray photoelectron spectroscopy, Auger electron transmission microscopy to characterize electropolished NiTi coated...
This study examined the efficacy of computed tomography (CT)-based Hounsfield units (HU) as early predictors aseptic bone necrosis, a serious post-cranioplasty complication after autologous cranioplasty. In total, 100 patients who underwent decompressive craniectomy and subsequent cranioplasty were included. The radiodensity flap was evaluated in HU from CT scans at five follow-up timepoints. thresholds established to predict development necrosis. demonstrated declining trend throughout...
Positional skull deformities have been on the rise for decades and can be treated with molding helmets in early childhood. Parents often fear later cosmetic stigmatization, but also a reduced quality of life (QoL) during treatment. The aim this study was to examine therapy results our patient collection from new perspective. Cranial vault asymmetry (CVA), cranial index (CVAI), (CI) were compared before after helmet therapy. Correction defined by decrease CVA <3.5 mm CI <90%. Subjective...