Artem Rafaelian

ORCID: 0000-0003-4447-6919
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Research Areas
  • Glioma Diagnosis and Treatment
  • Brain Metastases and Treatment
  • Meningioma and schwannoma management
  • Nanoplatforms for cancer theranostics
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Intracranial Aneurysms: Treatment and Complications
  • Spinal Fractures and Fixation Techniques
  • Surgical Simulation and Training
  • Management of metastatic bone disease
  • Corneal surgery and disorders
  • Cerebral Venous Sinus Thrombosis
  • Anatomy and Medical Technology
  • Anesthesia and Neurotoxicity Research
  • Head and Neck Cancer Studies
  • Nitric Oxide and Endothelin Effects
  • Sinusitis and nasal conditions
  • Intensive Care Unit Cognitive Disorders
  • Neurosurgical Procedures and Complications
  • Intraoperative Neuromonitoring and Anesthetic Effects
  • Photodynamic Therapy Research Studies
  • Traumatic Brain Injury Research
  • Virtual Reality Applications and Impacts
  • Facial Nerve Paralysis Treatment and Research
  • Prostate Cancer Treatment and Research
  • Inflammatory Biomarkers in Disease Prognosis

University of Rostock
2023-2025

Universitätsmedizin Rostock
2025

S. M. Kirov Military Medical Academy
2023-2024

Purpose Recently, the temporalis muscle thickness on cranial CT scan was proposed as a surrogate marker for patients’ baseline frailty that correlates with outcome in primary and metastatic brain tumor patients. In this study, we investigated whether velocity of atrophy (TMA) affects patients cerebral metastases. Methods We analyzed radiological clinical data sets 96 who received craniotomy metastasis resection our institution. then correlated course after stratification atrophy. Results The...

10.3389/fonc.2025.1482705 article EN cc-by Frontiers in Oncology 2025-02-28

<title>Abstract</title> Purpose: An inverse association between the use of platelet inhibitors and risk cancer has been reported by numerous epidemiological studies in past. The effects antiplatelet agents on cerebral metastasis formation non-small cell lung (NSCLC) are largely unknown. We therefore, investigated effect inhibition NSCLC patients at time first diagnosis metastases. Methods: clinical course 417 with metastases who underwent craniotomy for resection during their disease....

10.21203/rs.3.rs-6194346/v1 preprint EN cc-by Research Square (Research Square) 2025-03-17

Background: Hydrogen peroxide (H2O2) is a well-known hemostatic and antiseptic agent in neurosurgical practice. While there are concerns regarding the use of H2O2 due to its potential for neuronal damage, pathophysiological effect on cells not clearly understood. Methods: An online survey concerning was conducted board-certified platform, an experimental study designed investigate tumor cells. Brain tissues mice brain/tumor humans were irrigated with 3%, 1.5%, NaCl 0.9%, processed by bipolar...

10.3390/ph18040533 article EN cc-by Pharmaceuticals 2025-04-06

Importance Variations in perioperative dexamethasone dosing are common brain metastasis resection, but their impact on patient outcomes remains unclear. Objective To evaluate the association between and outcomes, focusing overall survival (OS) progression-free (PFS). Design, Setting, Participants This retrospective multicenter comparative effectiveness study used data collected from January 2010 to December 2023. Patients with symptomatic metastases undergoing primary surgical resection at 7...

10.1001/jamanetworkopen.2025.4689 article EN cc-by-nc-nd JAMA Network Open 2025-04-11

Although the operating theatre offers unique didactic opportunities, it can be perceived as an uncomfortable environment by medical students due to lack of etiquette, time pressure and parallel work different disciplines. We investigated whether virtual reality training significantly reduce some these fears improve surgical education for students. randomly divided a group 24 effects application (digitally recreated tour) compared with currently in use written instructions operational tasks...

10.1016/j.wneu.2024.11.106 article EN cc-by World Neurosurgery 2024-12-01

is to assess the effectiveness and safety of stereotactic photodynamic therapy (sPDT) with 5-aminolevulinic acid (5-ALA) in patients recurrent malignant supratentorial gliomas functionally relevant brain areas.

10.17691/stm2024.16.2.06 article EN Sovremennye tehnologii v medicine 2024-04-27

Temporal muscle thickness (TMT) on cranial CT scans has recently been identified as a prognostic imaging parameter for assessing patient's baseline frailty. Here, we analyzed whether TMT correlates with Traumatic brain injury (TBI) severity and it can be used to predict outcome(s) after TBI. We the radiological clinical data sets of 193 patients TBI who were admitted our institution correlated outcomes stratification TMT. Our analyses showed significant association between high increased...

10.3390/jcm12247625 article EN Journal of Clinical Medicine 2023-12-11

Vertebrobasilar dolichoectasia is rare but in symptomatic cases thoroughly reduce quality of life and challenging for treatment. Current paper presentstwo vertebral that cause neurovascular compression syndromes. In both artery transposition performed using sling-technique. The aim the study – to demonstrate special features efficiency sling-technique conflicts caused by presented.Surgical video demonstrating particular technique also performed. Additionally, literature data on epidemiology,...

10.17650/1683-3295-2024-26-3-95-102 article EN Russian journal of neurosurgery 2024-09-07

Objectives Stereotactic photodynamic therapy (sPDT) using 5-aminolaevulinic acid (5-ALA) as a cytotoxic photosensitizer may be potentially prospective treatment option for malignant gliomas. Material and Methods We analyzed data from 10 patients with recurrent gliomas of the brain who were treated sPDT at Department Neurosurgery Military-Medical Academy S. M. Kirov, 2020 to November 2021. Three again after 3, 7, 15 months due relapse. Results The median age was 55.5 years, range 30–60 there...

10.25259/asjo-2022-69-(433) article EN cc-by-nc-nd Asian Journal of Oncology 2023-10-04

Abstract BACKGROUND Patients with brain metastases that undergo metastasis resection regularly receive perioperative dexamethasone. We sought to evaluate variation in pre- and post-operative dexamethasone dosing whether is linked patient outcome. METHODS This was a multicenter retrospective study collecting data on daily dosage over period of 27 days patients undergoing resection. Non arbitrary cutpoint selection performed using maximally selected rank statistics dichotomize patients....

10.1093/noajnl/vdae090.109 article EN cc-by-nc Neuro-Oncology Advances 2024-08-01

Abstract Background: COVID-19 has attracted global attention primarily because of the severe acute respiratory symptoms associated with it. However, nearly one third patients also present neurologic symptoms. This report describes a case previously healthy woman infection, who developed facial nerve palsy and rapid progression to coma due otogenic brain abscess. Case Description: A 63-year-old infection exhibited paresis, high fever purulent secretion from her left ear within 48 hours after...

10.1055/a-2479-5462 article EN Journal of Neurological Surgery Part A Central European Neurosurgery 2024-11-20
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