A5013172550- Hemodynamic Monitoring and Therapy
- Cardiac, Anesthesia and Surgical Outcomes
- Non-Invasive Vital Sign Monitoring
- Ultrasound in Clinical Applications
- Sepsis Diagnosis and Treatment
- Blood Pressure and Hypertension Studies
- Respiratory Support and Mechanisms
- Cardiovascular Health and Disease Prevention
- Intensive Care Unit Cognitive Disorders
- Cardiac Arrest and Resuscitation
- Renal function and acid-base balance
- Electrical and Bioimpedance Tomography
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Cardiovascular Function and Risk Factors
- Heart Rate Variability and Autonomic Control
- Traumatic Brain Injury and Neurovascular Disturbances
- Anesthesia and Sedative Agents
- Healthcare Technology and Patient Monitoring
- Anesthesia and Neurotoxicity Research
- Mechanical Circulatory Support Devices
- Airway Management and Intubation Techniques
- Cardiovascular Issues in Pregnancy
- Pulmonary Hypertension Research and Treatments
- Anesthesia and Pain Management
- Cardiac Valve Diseases and Treatments
University of Rostock
2011-2025
Universitätsmedizin Rostock
2015-2024
Gemeinsamer Bundesausschuss
2024
University Medical Center
2021-2024
Klinikum Ludwigsburg
2024
University Hospital and Clinics
2022
Universität Hamburg
2010-2019
University Medical Center Hamburg-Eppendorf
2010-2019
Cleveland Clinic
2019
Committee on Publication Ethics
2019
Perioperative fluid therapy remains a highly debated topic. Its purpose is to maintain or restore effective circulating blood volume during the immediate perioperative period. Maintaining and pressure are key components of assuring adequate organ perfusion while avoiding risks associated with either hypo- hyperperfusion. Relative therapy, three inescapable conclusions exist: overhydration bad, underhydration what we assume about status our patients may be incorrect. There wide variability...
Abstract We build a publicly available database that tracks economic activity in the United States at granular level real time using anonymized data from private companies. report weekly statistics on consumer spending, business revenues, job postings, and employment rates disaggregated by county, sector, income group. Using data, we show how COVID-19 pandemic affected economy analyzing heterogeneity its effects across subgroups. High-income individuals reduced spending sharply March 2020,...
Abstract Introduction Several single-center studies and meta-analyses have shown that perioperative goal-directed therapy may significantly improve outcomes in general surgical patients. We hypothesized using a treatment algorithm based on pulse pressure variation, cardiac index trending by radial artery contour analysis, mean arterial study group (SG), would result reduced complications, length of hospital stay quicker return bowel movement postoperatively abdominal patients, when compared...
Haemodynamic monitoring and management are cornerstones of perioperative care. The goal haemodynamic is to maintain organ function by ensuring adequate perfusion pressure, blood flow, oxygen delivery. We here present guidelines on "Intraoperative adults having non-cardiac surgery" that were prepared 18 experts behalf the German Society Anaesthesiology Intensive Care Medicine (Deutsche Gesellschaft für Anästhesiologie und lntensivmedizin; DGAI).
In Brief Objective The method of determining continuous cardiac output (CO) with beat-to-beat pulse-contour analysis calibrated by transthoracic thermodilution is gaining much wider clinical acceptance. However, some questions have been raised regarding the reliability this during periods profound hemodynamic instability. We validated original calculation and a new, improved algorithm against thermodilution-derived measurements CO in patients changes >20%. Design Comparative study. Setting...
Objective Stroke volume variation as measured by the analysis of arterial pressure waveform enables prediction responsiveness in ventilated patients with normal cardiac function. The aim this study was to investigate ability monitoring stroke predict and assess changes preload reduced left ventricular function after surgery. Design Prospective study. Setting University hospital. Patients Fifteen mechanically a ejection fraction <0.35 (study group) 15 an >0.50 (control coronary artery bypass...
Objective Severe systemic inflammation with a vasodilatory syndrome occurs in about one third of all patients after cardiac surgery cardiopulmonary bypass. Hydrocortisone has been used successfully to reverse vasodilation septic patients. We evaluated if stress doses hydrocortisone attenuate severe inflammatory response predefined risk group Design Randomized, nonblinded, controlled trial. Setting Anesthesiologic intensive care unit for surgical an university hospital. Patients After...
Abstract Background: The authors hypothesized that goal-directed hemodynamic therapy, based on the combination of functional and volumetric parameters, improves outcome in patients with cardiac surgery. Therefore, a therapy guided by stroke volume variation, individually optimized global end-diastolic index, mean arterial pressure was compared an algorithm central venous pressure. Methods: This prospective, controlled, parallel-arm, open-label trial randomized 100 coronary artery bypass...
Vasopressors are commonly applied to restore and maintain blood pressure in patients with sepsis. We aimed evaluate the current practice therapeutic goals regarding vasopressor use septic shock as a basis for future studies provide some recommendations on their use. From November 2016 April 2017, an anonymous web-based survey of vasoactive drugs was accessible members European Society Intensive Care Medicine (ESICM). A total 17 questions focused profile respondents, triggering factors, first...
Fluid and volume therapy is an important cornerstone of treating critically ill patients in the intensive care unit operating room. New findings concerning vascular barrier, its physiological functions, role regarding leakage have lead to a new view fluid administration. Avoiding hypervolemia, as well hypovolemia, plays pivotal when both perioperatively unit. The various studies comparing restrictive vs. liberal management are not directly comparable, do differ (in most instances) between...
Abstract Background This study compares the analgesic indices Analgesia Nociception Index (heart rate variability), Surgical Pleth (photoplethysmography), and pupillary dilatation, to heart rate, mean arterial pressure, bispectral index, with regard diagnostic accuracy prediction probability for nociceptive response. The primary endpoint was correlation between Δ values remifentanil dose administered. Methods We anesthetized 38 patients propofol increasing doses of applied standardized...
Treatment decisions on critically ill patients with circulatory shock lack consensus. In an international survey, we aimed to evaluate the indications, current practice, and therapeutic goals of inotrope therapy in treatment shock.
It is unclear whether optimising intraoperative cardiac index can reduce postoperative complications. We tested the hypothesis that maintaining optimised postinduction during and for first 8 h after surgery reduces incidence of a composite outcome complications within 28 days compared with routine care in high-risk patients having elective major open abdominal surgery.