- Adhesion, Friction, and Surface Interactions
- Sports injuries and prevention
- Tendon Structure and Treatment
- Mechanical stress and fatigue analysis
Wageningen University & Research
2023-2024
Abstract Hard ticks feed on their host for multiple days. To ensure firm attachment, they secrete a protein-rich saliva that eventually forms solid cement cone. The underlying mechanism of this liquid-to-solid transition is currently not understood. This study focuses the phase transitions disordered glycine-rich protein (GRP) found in tick saliva. We show GRP undergoes liquid–liquid separation via simple coacervation to form biomolecular condensates salty environments. Cation– π and –...
Abstract Hard ticks feed on their host for multiple days. To ensure firm attachment, they secrete a protein-rich saliva that eventually forms solid cement cone. The underlying mechanism of this liquid-to-solid transition is not yet understood. This study focuses the phase transitions disordered glycine-rich protein (GRP) prominent in tick saliva. We show GRP undergoes liquid-liquid separation via simple coacervation to form biomolecular condensates salty environments. Cation-pi and pi-pi...