A5065900975- Vitamin K Research Studies
- Viral Infectious Diseases and Gene Expression in Insects
- Fatty Acid Research and Health
- Cardiovascular Disease and Adiposity
- Cardiovascular Function and Risk Factors
- S100 Proteins and Annexins
- Biomarkers in Disease Mechanisms
Monash University
2024
Queen's University
2017
Abstract Aging is associated with chronic, low‐level inflammation which may contribute to cardiovascular pathologies such as hypertension and atherosclerosis. This chronic be opposed by endogenous mechanisms limit inflammation, for example, the actions of annexin A1 (ANXA1), an glucocorticoid‐regulated protein that has anti‐inflammatory pro‐resolving activity. We hypothesized mediator ANXA1 protects against age‐induced changes in blood pressure (BP), structure function, cardiac senescence....
Abstract Background Diabetic heart disease may eventually lead to failure, a leading cause of mortality in diabetic individuals. The lack effective treatments for diabetes-induced failure result from address the underlying pathological processes, including chronic, low-grade inflammation. Previous studies have reported that lipoxin A 4 (LXA ), known promote resolution inflammation, attenuates atherosclerosis, but its impact on hearts has not been sought. Thus, we aimed determine whether LXA...