To study the antioxidative and protective properties of aqueous extract Hammada scoparia (H. scoparia) against effects sub-chronic aluminium (Al) intoxication on mnemonic process some neurochemical markers. Al was administered intraperitoneally (50 mg/kg body weight, three times a week), H. malic acid were given orally by gavage at daily dose (100 weight) to rats for 90 days. caused significant short-term long-term memory disturbances, decrease in locomotor activity, inhibition...

Lead is one of the environmental pollutants that can threat life living creatures in many ways. This study was carried out to investigate effect lead exposure on kidney function. Fourteen male Wistar rats were divided into 2 groups; group 1 given a tap water diet and 1000 ppm acetate drinking for 8 weeks. concentration blood determined by atomic absorption. The results showed an increase calcium blood. same happened phosphaturia administered with Pb compared control group. these parameters...

Recently, we identified that olive leaf extract (OLE) prevents lead (Pb)-induced abnormalities in behavior and neurotransmitters production chronic Pb exposure rats. The aim of the present study was to provide additional evidence OLE acts as an anti-apoptotic, anti-inflammatory, antioxidant mediator exposed 4-weeks old Wistar rats were or not 250 mg/l for 13-weeks then tap water containing 0.1% 2-weeks. Atomic absorption spectrophotometry showed significantly elevated levels hippocampus...

Lead is an industrial pollutant that may exert specific toxic effects on male mammals. The aim of this study was to investigate further the protective vitamin E lead acetate (Pb)-induced reproductive toxicities and genotoxic rats. Sexually mature Wistar rats (weighing 120-160 g) were given Pb (20 mg/Kg) (600 mg/kg/rat) orally for 20 days. sperm count, motility, morphology, chromosomal aberrations, FSH, LH testosterone levels, histopathological changes in testes investigated after Results...

Lead poisoning is a potential factor in brain damage, neurochemical dysfunction and severe behavioral problems. Considering this effect, our study was carried out to investigate the effects of wormwood restore enzymes activities, lipid peroxidation changes induced by lead.Thirty Wistar rats were divided into five groups (n = 6 each group): three exposed 750 ppm lead acetate drinking water for 11 weeks two as control. Aqueous extract (200 mg/kg body weight) administrated intoxicated...

Background and Objective: Aluminium (Al) is a widely recognized neurotoxin that inhibits more than 200 biologically important functions inducing severe behavioral abnormalities, impaired cognitive metabolic dysfunction.The present study was designed to investigate oxidative stress of aluminium induced toxicity in developing rat brain enlarged the possible ameliorating role omega-3 omega-6 fatty acids with low high ratio.Methodology: administered intraperitoneally (100 mg kgG 1 b.wt., twice...

Abstract The essential oil of Glycyrrhiza glabra leaves was obtained by hydrodistillation and analyzed GC GC-MS. Other parameters such as refractive index, optical rotation; density, polarimetric deviation; freezing point Solubility in ethanol are also measured. main hydrocarbon oxygen containing compounds were: Isoniazid (13.36 %) ; Diethyltoluamide (6.56 %), Benzoic acid (5.37 Benzene (4.58 Linalool (2.25 Prasterone (5.63 Warfarin (1.43 Iodoquinol (1.90 Phenol, 4-(2-aminopropyl) (1.30 %)....

'Rosmarinus officilnalis' is a plant used in Mediterranean diet and traditional medicine, possessing various antioxidant cytoprotective bioactivities. In this study, we investigated the potential neuroprotective efficacy of aqueous Rosemary extract (AER) against neurotoxicity induced by Aluminum (Al), terms behavioral, biochemical histological aspects young rats. an intraperitoneal injection Al, at weekly dose 60mg/Kg was given to animals. A treatment 150mg/Kg/day AER administered gavage...

Aristolochia longa (from the family Aristolochiaceae) is widely used for cancer treatment in Algerian traditional medicine. The aim of present study was to investigate cytotoxic and apoptogenic activities. phytochemical composition acute toxicity aqueous extracts roots A. from Algeria. An extract (decoction) dried prepared. effects this were then evaluated Burkitt’s lymphoma BL41 cells, by flow cytometry. induction apoptosis assessed two corroborative assays: propidium iodide staining cell...

Lead is industrial pollutant that may have toxic effects on the male. The aim of this study was to further investigate protective vitamin E lead acetate (Pb) induced reproductive toxicities and genotoxicity in male rat. Sexually mature Wistar rats (weighing 120-160 g) were given Pb (20 mg/Kg) (600 mg/kg/rat) orally for 20 days. sperm counts, motility, morphology, chromosomal aberrations, FSH, LH testosterone levels, histopathological changes testes these rats, investigated at end Result...

Introduction The diesters of 1,2-benzenedicarboxylic acid (phthalic acid), commonly known as phthalates, are used primarily plasticizers polyvinyl chloride and additives in consumer personal care products. Objective This study was designed to evaluate the impact utero postnatal exposure diisononyl phthalate (DINP), diethylhexyl (DEHP), diethyl (DEP) on gut maturation a Wistar rat model. Materials Methods Pregnant females were gavaged from day 8 gestation through (pd) 30 with 0 (vehicle...

Separation membranes have gained attention as promising options for water and wastewater treatment due to their financial sustainability, eco-friendliness. However, practical challenges limited application in separation. To overcome these limitations, inorganic-organic hybrid been developed this study. The present work deals with two attractive aspects: (i) economical, through the valorization of a local clay (Algerian kaolin), (ii) environmental, which is based on membrane selectivity metal...

The ability of Wormwood (Artemisia absinthium L.) extract (A.Ab) to restore membrane-bound enzymes like Na(+)-K(+)-ATPase, Ca(++)-ATPase, Mg(++)-ATPase, and oxidative damage induced by lead were investigated. Rats exposed acetate (750 ppm) for 11-weeks treated during 4-weeks with A.Ab. Lipid levels, ATPase activity, thiobarbituric acid reactive substances (TBARS), proteins carbonyl estimated. In liver kidney, inhibited increased (P < 0.05) the levels cholesterol, triglycerides, free fatty...

Previous human and experimental studies have demonstrated that lead exposure may modify the metabolism of lipid. Oxidative stress with subsequent lipid peroxidation has been postulated as one mechanism for toxicity. The protective action vitamins C against affects hydroperoxide level liver functions in male rats studied. Experiments were performed on waster body weights 120-160 g. Male wistar exposed to 3 g/l acetate drinking water 5 weeks treated thereafter vitamin (500 mg/kg, orally) 28...

The leaf essential oil of Ajuga iva growing wild in Mascara region situated the North West Algeria, has been obtained by hydrodistillation and analyzed GC GC-MS. We proposed to determine physicochemical, organoleptic chemical identification these components. Twenty two volatile compounds were identified which included: dienestrol (54.04%), eucalyptol (27%), o-xylene (7.98 %), 1-octadecanol (5.80%); 3-carene (4.46%), (E)-2,3,6- trimethoxypentafulvene-1-carbonitrile (4.34%), (-)-spathulenol...

A pollen analysis of Algerian honey was conducted on a total 10 samples. The samples were prepared using the methodology described by Louveaux et al., that then further adapted Ohe al. subsequently observed light microscopy. 36 taxa discovered and could be identified in analyzed Seventy percent studied belonged to group ofmonofloral honeys represented Eucalyptus globulus, Thymus vulgaris, Citrus sp. Lavandula angustifolia. Multifloral comprised 30% samples, with grains stoechas (28.49%)...

Pregnant rats received 0, 2% of lead acetate (Pb) in drinking water.The treatment with the aqueous extract Pimpinella anisum L (P.A.E.) started after weaning dose 750 mg/kg and for 15 successive days .The effect was evaluated through behavioral tests : open filed (OF) , Forced swimming test ( FST) dark /light .Beside; Lactate dehydrogenase (LDH), total plasmatic proteins, alkaline phosphatase (ALP), lipid peroxidation (TBARS) Catalase (CAT) were analyzed.Lead induced a hyperactivity field...

Background and Objective: Artemisia absinthium L. has long been used as traditional herbal medicine for the treatment of gastric pain, cardiac stimulation to improve memory restore declining mental function.Aim present study was designed investigate effects on cerebral oxidative stress induced by mercury.Aqueous extract (AEAA) (500 mg LG 1 b.wt.dayG ) administered orally experimental rat brain injury administration HgCl 2 (5 kgG b.wt., i.p.).Methodology: The activities superoxide dismutase...

Effects of ROS generation have been postulated to be major contributors lead-exposure related disease. The aim the study was investigate effect aqueous extract wormwood (Artemisia absinthium) on oxidative stress in rats protractedly exposed lead. Aqueous plant administered orally (200 mg x kg(-1) body weight). Plasma vitamin C, E and non-protein thiol concentrations, red blood cells (RBC) thiobarbituric acid reactive substances, reduced glutathione levels haemolysis test were evaluated. In...

Oxidative stress was induced by lead acetate (Pb) in Raphanus sativus seedlings grown a hydroponic system using sand as substrate. Thirty day old acclimated seeds were treated for 7 days with five Pb levels (0 control, 100, 200, 500 and 1000 mg l-1). Parameters such growth, oxidative damage markers (lipid peroxidation, protein oxidation hydrogen peroxide contents) enzymatic activities of catalase (CAT) peroxidase (POD) investigated. Lead concentration plant tissues increased increasing...

We have compared the activity of 5-aminolevulinate dehydratase (5-ALAD) with amount protein detected by specific antibodies in rocket immunoelectrophoresis. Parallel kinetic evolutions enzymic and antigen were observed radish (Raphanus sativus L.) cotyledons, both complete darkness or under standard far red light involving phytochrome. However, treatment seedlings gabaculine leads to an important decrease activity, while content is maintained. This inhibition not overcome addition glutamic...