The aim of the present study was to evaluate total phenolic and lipid content, fatty acids profiles in vitro antioxidant activities aqueous solvent extracts red seaweed Asparagopsis taxiformis, through six different investigations. demonstrated that phenol contents (mg gallic acid/g dry weight) were highest methanolic extracts, followed by ethanolic, hydroethanolic hydromethanolic extracts. lowest identified three remaining extracts: Butanolic, petroleum ether acetone Furthermore, content...

Effects of ROS generation have been postulated to be major contributors lead-exposure related disease. The aim the study was investigate effect aqueous extract wormwood (Artemisia absinthium) on oxidative stress in rats protractedly exposed lead. Aqueous plant administered orally (200 mg x kg(-1) body weight). Plasma vitamin C, E and non-protein thiol concentrations, red blood cells (RBC) thiobarbituric acid reactive substances, reduced glutathione levels haemolysis test were evaluated. In...

Purpose The purpose of this study is to determine the effect olive cake (CO) on glycaemia and lipemia lipid peroxidation antioxidant enzymes activities in erythrocytes tissues, streptozotocin (STZ)-induced diabetic rats. Design/methodology/approach Diabetes was induced by a single intraperitoneal injection STZ (55 mg/kg BW). In total, 12 D rats, weighing 260 ± 20 g, were divided into two groups fed casein diet supplemented (D-OC) or not (D) with OC (7.5 per cent), for four weeks. Findings...

Purpose This paper aims to study the effects of Zygophyllum album (Za) ( Z. ) in hypercholesterolemic-diabetic rats. Design/methodology/approach Male Wistar rats n = 36) weighing 200 ± 10 g, consumed an experimental diet containing 20 per cent casein were divided into three groups 12). The first group enriched with 1 cholesterol (CH), second is rendered diabetic by intraperitoneal injection streptozotocin (STZ) (35 mg/kg body weight) (D) (DM). third hypercholesterolemic and STZ-induced...

Purpose This study aims to investigate the possible effect of Citrus latifolia (CL) extract on biomarkers oxidative stress, including lipid peroxidation products in rats fed a high cholesterol diet Design/methodology/approach Hypercholesterolemia was induced by feeding normocholesterolemic 1 per cent cholesterol-enriched for 15 days. An experimental group ( n = 20) divided into two groups 10) and same with or without CL lyophilized aqueous (1 cent) four weeks. At day 28, ten from each were...

Journal of Pharmaceutical Research International (ISSN: 2456-9119) is dedicated to publish high quality papers in all areas pharmaceutical Science including drugs, community pharmacy, hospital clinical compounding consultant internet veterinary nuclear military pharmacy informatics, pharmaceutics, medicinal chemistry, pharmacognosy, pharmacotherapy, pharmacodynamics, pharmacokinetics, pharmacology, neuropharmacology, psychopharmacology, pharmacogenetics, pharmacogenomics,...

Purpose This paper aims to study the effects of a diet supplemented with flaxseeds on dyslipidemia, oxidative stress and proinflammatory cytokines, in rats consuming high-cholesterol diet. Design/methodology/approach Male Wistar ( n = 30) weighing (250 ± 5 g) which 10 were control 20 rendered hypercholesterolemic (HC) by feeding enriched 1% cholesterol, for 15 days. After this phase, divided into two groups; group 10), fed 20% casein cholesterol; same but additionally (Linum usitatissimum)...

The aim of this study was to investigate the antihyperglycemic and antioxidant effects Po (Portulaca oleracea) lyophilised aqueous extract in diabetic male Wistar rats.Diabetes induced intraperitonially by a single injection STZ (streptozotocin) (60 mg/kg bw (body weight)).Twenty rats, weighing 263 ± 5 g, were divided into two groups fed casein diet supplemented or not with (1 g/kg bw), for four weeks.Control group (n = 6) received 0.23~0.25 mL citrate buffer standard during experiment.The...

Purpose This paper aims to study the effect of green lemon zest combined with sardine proteins in diabetic hypertensive rats (DHRs). Design/methodology/approach Male Wistar ( n = 30) weighing 250 ± 10 g were divided into five groups. The first group consumed a diet containing 20 per cent casein (C). other four groups are rendered by intraperitoneal injection streptozotocin (40 mg/kg body weight), then subcutaneous implantation controlled time-release pellet ouabain (0.25 mg/pellet). One...

Purpose This paper aims to investigate the preventive effects of a concomitant supplementation lyophilized aqueous extract Globularia alypum (Ga) leaves in high cholesterol-diet (HC-D) on lipid profile and lecithin cholesterol acyltransferase (LCAT) activity hypercholesterolemic rats. Design/methodology/approach Twenty-four male Wistar rats weighing 232 ± 10 g were divided into four groups (n = 6). Two control fed standard-diet (St-D) supplemented (C- Ga ) or not (C) with 1.66% leaf extract....

Objective: The purpose of this study was to investigate the possible protective effects Zygophyllum gaetulum aqueous extract on hypercholesterolemia and oxidative stress in rats fed a high-cholesterol diet. Methods: Twelve hypercholesterolemic were divided into two groups 20% casein diet enriched with 1% cholesterol + 0.5% cholic acid supplemented (HC-Zg) or not (HC) Z.gaetulum (1%), for 4 weeks. Results: In HC-Zg group compared HC group, plasma total low density lipoprotein...

Aim: In this study, we determine the effects of supplementation sardine protein, Citrus latifolia extract and combination both on lecithin: cholesterol acyltransferase paraoxonase-1 activities in hypercholesterolemic rats.

Purpose The purpose of this study is to evaluate the effects flaxseed ( L. usitatissimum [Linn]) on blood pressure, redox status markers and acetylcholinesterase enzyme activity in ouabain-induced hypertension normal Wistar rats. Design/methodology/approach Male rats weighing 250 ± 7 g n = 24) fed with an experimental diet containing 20 per cent casein were divided into three groups 8) received a daily subcutaneous injection either 0.9 saline solution (T group) or 10 µg/kg/day ouabain...

Globularia alypum (G. alypum) is a medicinal plant commonly used intradi-tional pharmacopoeias. In this study, the antioxidant and anti-inflammatory activities of G. lyophilized aqueous extract were evaluated. Male Wistar rats (n=24) weighing 232±10g divided into 4 groups (n=6). Two control fed standard-diet (St-D) supplemented (C-Ga) or not (C) with 1.66% extract. The two others enriched choles-terol diet (EC-D) for 15 days, which contains St-D plus 1% cholesterol 0.5% cholic acid (HC) same...

Diabetes is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, action, or both. The chronic diabetes associated with long-term damage, dysfunction, and failure various organs. Accordingly, the current study we have investigated effect clove on lipid metabolism, oxidative stress-induced inflammation response diabetic rats. was induced intraperitonially single injection streptozotocin (STZ). treated received daily orally extract, for 4...

This study was undertaken to estimate antioxidant and anti-hemolytic activi-ties of different parts (leaves, stem heart) the artichoke (Cynara scoly-mus L) cooked with methods. The leaves, stems hearts were used either raw or according four cooking methods: evaporated, boiled, oven-baked sautéed. On extracts prepared from (raw cooked), total polyphenols flavonoids contents, anti-oxidant activities evaluated. According methods, polyphenol contents baked leaves highest. Polyphenol higher in...

Beneficial Effects of Sardine Proteins Combined with Citrus latifolia Extract on Lipid profile and Tissues Redox Status in Rats fed a High-Cholesterol Diet Considerable evidences support the role oxidative stress development atherosclerosis related cardiovascular diseases. Moreover, feeding experimental animals high cholesterol diet (HCD) was reported to increase induce reactive oxygen species (ROS) generation different biological tissues including liver, brain, kidney erythrocytes. Also,...

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