A5094181673- Liver Disease Diagnosis and Treatment
- Hepatitis B Virus Studies
- Liver Disease and Transplantation
- Cancer, Lipids, and Metabolism
- Organ Transplantation Techniques and Outcomes
- Helicobacter pylori-related gastroenterology studies
- Potassium and Related Disorders
- Organ Donation and Transplantation
- Hepatitis C virus research
- Cancer-related molecular mechanisms research
- Liver Diseases and Immunity
- Gastroesophageal reflux and treatments
- Alcohol Consumption and Health Effects
Harvard University
2024-2025
Beth Israel Deaconess Medical Center
2024-2025
Background Direct-acting antivirals (DAAs) have revolutionized hepatitis C virus (HCV) treatment. The changing landscape of hepatocellular carcinoma (HCC) in liver transplant (LT) recipients lacks a thorough description the outcomes HCC based on etiology. Objective To assess waitlist (WL) dropout and graft survival LT candidates etiology post-DAA era. Methods This retrospective cohort study analyzed United Network Organ Sharing/Organ Procurement Transplant data from 2015 to 2022. Graft was...
Objectives: Acute liver failure (ALF) is associated with high morbidity and mortality. Timely transplantation (LT) the only universally accepted therapy for ALF that non-responsive to medical therapy. Data regarding use of living donor LT (LDLT) this indication in US scarce. Materials Methods: United Network Organ Sharing/Organ Procurement Transplantation (UNOS/OPTN) data from January 2002 December 2020 were reviewed. Adult pediatric recipients listed as status 1 included. Demographics,...
Autoimmune hepatitis (AIH) is a varied inflammatory chronic liver disease. AIH’s prevalence varies and has increased recently. Diagnosis involves the discovery of histologic features following biopsy serologic testing. Clinical vary, up to 40% patients may be asymptomatic. Evaluating thiopurine methyltransferase (TMPM) activity before treatment crucial for an optimal response. The primary goal biochemical remission, normalized serum IgG, enzymes. Induction therapy typically azathioprine...
(1) Background: Hepatocellular carcinoma (HCC) contributes to the significant burden of cancer mortality in United States (US). Despite highly efficacious antivirals, chronic viral hepatitis (CVH) remains an important cause HCC. With advancements therapeutic modalities, along with aging population, we aimed assess contribution CVH HCC-related US between 1999–2020. (2) Methods: We queried all deaths related and HCC multiple-causes-of-death files from CDC Wide-ranging Online Data for...