A5101764566- Bacteriophages and microbial interactions
- Monoclonal and Polyclonal Antibodies Research
- Protist diversity and phylogeny
- Microbial Community Ecology and Physiology
- RNA and protein synthesis mechanisms
- Bacterial Genetics and Biotechnology
- Antimicrobial Peptides and Activities
Sichuan Agricultural University
2024
Abstract Novel therapeutic strategies against difficult-to-treat bacterial infections are desperately needed, and the faster cheaper way to get them might be by repurposing existing antibiotics. Nanodelivery systems enhance efficacy of antibiotics guiding their targets, increasing local concentration at site infection. While recently described nanodelivery promising, they generally not easy adapt different lack biocompatibility or specificity. Here, created that source targeting proteins...
Abstract The rise of antibiotic resistance, coupled with a dwindling pipeline, presents significant threat to public health. Consequently, there is an urgent need for novel therapeutics targeting antibiotic‐resistant pathogens. Nisin, promising peptide antibiotic, exhibits potent bactericidal activity through mechanism distinct from that clinically used antibiotics. However, its cationic nature leads hemolysis and cytotoxicity, which has limited clinical application. Here, nanodelivery...