F. Costa

ORCID: 0009-0003-1670-3771
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Research Areas
  • Cancer Treatment and Pharmacology
  • Advanced Breast Cancer Therapies
  • HER2/EGFR in Cancer Research
  • Ureteral procedures and complications
  • Advanced Radiotherapy Techniques
  • Appendicitis Diagnosis and Management
  • Cardiovascular and Diving-Related Complications
  • Radiation Dose and Imaging
  • Antifungal resistance and susceptibility
  • Traumatic Brain Injury and Neurovascular Disturbances
  • RNA Interference and Gene Delivery
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Erythrocyte Function and Pathophysiology
  • Phagocytosis and Immune Regulation
  • Abdominal Trauma and Injuries
  • Colorectal Cancer Surgical Treatments
  • Congenital Heart Disease Studies
  • Central Venous Catheters and Hemodialysis
  • Diverticular Disease and Complications
  • Radiomics and Machine Learning in Medical Imaging
  • Pituitary Gland Disorders and Treatments
  • Anorectal Disease Treatments and Outcomes
  • Effects of Radiation Exposure
  • Vascular Procedures and Complications
  • Colorectal and Anal Carcinomas

Universidade Estadual de Londrina
2000-2025

Hospital Pró-Cardíaco
2023

University of Lisbon
2015

Institut Claudius Regaud
2010

Hospital Sírio-Libanês
2010

Hospital Amaral Carvalho
2010

Faculdade de Medicina do ABC
2010

Hospital Universitario 12 De Octubre
2010

This work reports on the use of two different Monte Carlo codes (GEANT4 and MCNPX) for assessing dose reduction using bismuth shields in computer tomography (CT) procedures order to protect radiosensitive organs such as eye lens, thyroid breast. Measurements were performed head body PMMA phantoms an ionisation chamber placed five positions phantom. Simulations estimate Computed Tomography Dose Index values GEANT4 MCNPX. The relative differences between measurements simulations <10 %. arising...

10.1093/rpd/ncv059 article EN Radiation Protection Dosimetry 2015-03-25

Abstract Background: Sorafenib (SOR) is an oral multikinase inhibitor with antiangiogenic and antiproliferative activity. We previously reported data from the primary analysis of SOLTI-0701 demonstrating a progressionfree survival (PFS) benefit regimen SOR + capecitabine (CAP) vs placebo (PL)+CAP in patients advanced breast cancer (BC). Here we describe overall (OS), secondary endpoint SOLTI-0701. Methods: multinational (Brazil, France, Spain) phase 2b study HER2-negative locally or...

10.1158/0008-5472.sabcs10-p2-16-01 article EN Cancer Research 2010-12-01

1073 Background: Two phase IIb trials in pts with advanced BC demonstrated activity for SOR plus standard chemotherapy the primary endpoint of PFS. In Study A, median PFS + capecitabine (CAP) versus PL+CAP was 6.4 4.1 mo (hazard ratio [HR] 0.58; 1-sided p=0.0006). B, paclitaxel (PAC) PL+PAC 6.9 5.6 (HR 0.79; p=0.09). both studies, randomization stratified by visceral status slight imbalances some covariates. We performed MVA to assess impact and prognostic factors on Methods: A: Pts (N=229)...

10.1200/jco.2010.28.15_suppl.1073 article EN Journal of Clinical Oncology 2010-05-20

O forame oval patente (FOP) é o tipo de shunt interatrial mais comum, com prevalência entre 25 e 27% da população adulta. Tem funcionamento flap-like geralmente assintomático. Em alguns casos, pode estar associado a complicações clínicas como acidente vascular encefálico (AVE), embolia paradoxal, síndrome platipneia-ortodeóxia apneia do sono obstrutiva. diagnóstico se impõe principalmente em pacientes jovens que apresentam AVE, sem outro fator risco aparente. A avaliação FOP comumente...

10.36660/abcimg.20230020 article PT cc-by ARQUIVOS BRASILEIROS DE CARDIOLOGIA - IMAGEM CARDIOVASCULAR 2023-06-27

No AccessJournal of UrologyPEDIATRIC UROLOGY1 Aug 2000SEGMENTAL URETERAL NECROSIS DUE TO ACUTE APPENDICITIS F. COSTA, L.T. MARCHESE, and M.B.L. FERNANDES COSTAF. COSTA More articles by this author , MARCHESEL.T. MARCHESE FERNANDESM.B.L. View All Author Informationhttps://doi.org/10.1016/S0022-5347(05)67405-8AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "SEGMENTAL APPENDICITIS." The Journal Urology, 164(2), pp....

10.1016/s0022-5347(05)67405-8 article EN The Journal of Urology 2000-08-01
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