A5100721198- IoT and Edge/Fog Computing
- Nanoplatforms for cancer theranostics
- RNA Interference and Gene Delivery
- Nanoparticle-Based Drug Delivery
- Microplastics and Plastic Pollution
- Antimicrobial agents and applications
- Water Quality and Pollution Assessment
- graph theory and CDMA systems
- Vanadium and Halogenation Chemistry
- Mobile Ad Hoc Networks
- Catalytic C–H Functionalization Methods
- Advanced Memory and Neural Computing
- biodegradable polymer synthesis and properties
- Age of Information Optimization
- Immunotherapy and Immune Responses
- Heat shock proteins research
- Security in Wireless Sensor Networks
- Advanced biosensing and bioanalysis techniques
- Mathematical Approximation and Integration
- Cryptography and Data Security
- Endoplasmic Reticulum Stress and Disease
- Bioactive natural compounds
- Matrix Theory and Algorithms
- Multimedia Communication and Technology
- Video Analysis and Summarization
Jiangxi Science and Technology Normal University
2024
Changchun University of Science and Technology
2021-2024
National University of Singapore
2024
Nankai University
2014-2023
State Key Laboratory of Medicinal Chemical Biology
2018-2023
Tianjin University of Commerce
2023
The University of Texas at San Antonio
2022
State Key Laboratory of Polymer Physics and Chemistry
2018-2019
Auckland University of Technology
2019
Tianjin University
2019
Prostate-specific antigen (PSA) is an intercellular glycoprotein produced primarily by the prostate gland, which commonly chosen as initial target for early diagnosis of cancer. In this work, we demonstrate a simple yet sensitive sandwich-type single-particle enumeration (SPE) immunoassay quantitative detection PSA in flow chamber. The design based on luminescence resonance energy transfer (LRET) between upconversion nanoparticles (UCNPs) and gold (GNPs). carboxyl group-functionalized UCNPs...
Abstract Immunogenic cell death (ICD), which in situ generates cancer vaccines and elicits protective cognate anticancer immunity, has brought brightness to immunotherapy. However, poor immunogenicity low response rate of current ICD‐inducing strategies restrict the development clinical application ICD‐based Herein, a novel calixarene, quaternary ammonium‐modified azocalix[4]arene (CA‐3) that drive bona fide ICD with high efficiency, is presented. In addition, unique macrocyclic structure...
In secure group communications, users of a share common key. A key server sends the to authorized new as well performs rekeying for whenever changes. this paper, we investigate scalability issues reliable rekeying, and provide performance analysis our management system (called keygem) based upon use trees. Instead after each join or leave, periodic batch improve alleviate out-of-sync problems among rekey messages between data messages. Our analyses show that can achieve large gains. We then...
Inspired by heat shock proteins (HSPs), a self-assembly nanochaperone (nChap) is developed as novel nanovaccine for boosting antitumor immune responses. Taking advantage of HSP-like microdomains and surface-decorated mannose, this nChap can efficiently capture antigens ferry them into the dendritic cells (DCs). Subsequently, blast lysosomes transforming structure property surface microdomains, thereby promoting antigen escape enhancing their cross-presentation in cytoplasm. As result,...
Abstract Personalized cancer vaccination using nanomaterials holds great potential for immunotherapy. Here, a nanochaperone (PBA‐nChap) is tailored in situ capture of tumor‐associated antigens (TAAs) to improve The PBA‐nChap capable i) efficiently capturing TAAs situ; ii) protecting from degradation; iii) transporting antigen‐presenting cells and promoting cross‐presentation. Intratumor injection combination with pretreatment photodynamic therapy (PDT) significantly enhances immune response...
ABSTRACT Taolimiao‐Alashan Nur (T‐A Nur) is an important breeding site for the Relict Gulls ( Larus relictus ) and many other waterbirds. To understand gut health status of rare bird species living there to protect these species, this study analyzed microbiota four waterbird including Gull L. ), Black‐necked Grebe Podiceps nigricollis Greylag Goose Anser anser Ruddy Shelduck Tadorna ferruginea using 16S rRNA high‐throughput sequencing. Results showed that had highest α‐diversity, while...
The ligand-switchable nanocarriers (LSNs) concealed CPPs into the bloodstream and expose them upon entering tumor sites, overall improving therapeutic effect.
Modern applications such as augmented reality, connected vehicles, video streaming and gaming have stringent requirements on latency, bandwidth computation resources.The explosion in data generation by mobile devices has further exacerbated the situation.Mobile Edge Computing (MEC) is a recent addition to edge computing paradigm that amalgamates cloud capabilities with cellular communications.The concept of MEC relocate network for yielding ultra-low high computation, bandwidth, low burden...
Serverless computing is a promising paradigm for delivering services to the Internet of Things (IoT) applications at edge network. Its event-triggered computation, as well fine-grained and agile resource scaling, well-suited resource-constrained environment. However, general-purpose auto-scalers that are predominant in cloud settings perform poorly serverless Edge. This mainly due difficulty quickly determining optimal allocation under resource-budget constraints dynamic workloads. In this...
pH-Reduction dual responsive nanocarriers (DRNs) achieve programmable release of CA4 and CDDP in cancer therapy.
Organic anion transporters 1 (OAT1) and 3 (OAT3) play important roles in the renal elimination of a range substrate molecules. Little is known about natural products that can modulate OAT1 OAT3 activities. The medullae Juncus effusus often used for treatment dysuria traditional Chinese medicine. To study interactions phytochemicals J. with human OAT3, bioactivity guided phytochemical investigation led to seven new phenanthrenoids along nine compounds, including eight benzophenone from...
With the continuous development of power Internet Things (PIoT), smart devices (SDs) have been widely used in electric inspections. Due to limited resources intelligent inspection SDs and distance overhead transmission lines, many tasks cannot be processed promptly. This paper proposes a multi-hop-based end-edge cooperative computing (MHCC) scheme address task processing IoT. We formulate multi-hop offloading problem that minimizes energy consumption with delay constraints. develop JDPSO...
In secure group communications, users of a share common key. A key server sends the to authorized new as well performs rekeying for whenever changes. this paper, we investigate scalability issues reliable rekeying, and provide performance analysis our management system (called keygem) based upon use trees. Instead after each join or leave, periodic batch improve alleviate out-of-sync problems among rekey messages between data messages. Our analyses show that can achieve large gains. We then...
Follistatin-like 1 (FSTL1) is a secreted bone morphogenetic protein (BMP) antagonist, and it plays crucial role in normal lung development. Deletion of Fstl1 leads to postnatal death mice due respiratory failure. To further explore the FSTL1 mouse development, we created transgene SFTPC-Fstl1 allele displaying significant epithelial overexpression all stages However, did not alter morphogenesis, differentiation function. Moreover, found that function was blocked by polarization, which...
The failure of the power communication network often leads to a cascading system. Evaluating potential risks in is crucial ensure stable operation This paper proposes comprehensive risk assessment method for qualitative and quantitative measures. Firstly, an index system assessment, considering both static structure dynamic operation, established. optimal weight each determined using combination game weighting method. Additionally, model established by coupling gray cloud theory...
Protein therapeutics have been viewed as powerful candidates for cancer treatment by virtue of highly specific bioactivity and minimized adverse effects. However, the intracellular delivery protein drugs remains enormously challenging due to multiple successive biological barriers in vivo. Herein, a bioinspired nanochaperone is developed assist proteins vanquishing sequential physiological holistic manner enhance synergistic tumor therapy. By concurrently mimicking N-terminal-binding domain...