- Poisoning and overdose treatments
- Drug-Induced Hepatotoxicity and Protection
- Cardiac Arrest and Resuscitation
- Restraint-Related Deaths
- Renal function and acid-base balance
- Pharmaceutical studies and practices
- Eosinophilic Esophagitis
- Pharmacology and Obesity Treatment
- Respiratory and Cough-Related Research
- Neuroscience of respiration and sleep
- Gastroesophageal reflux and treatments
- Respiratory viral infections research
- Psychosomatic Disorders and Their Treatments
- Epilepsy research and treatment
- Food Allergy and Anaphylaxis Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Pesticide Exposure and Toxicity
- Cannabis and Cannabinoid Research
- Methemoglobinemia and Tumor Lysis Syndrome
- Antimicrobial agents and applications
- Pediatric health and respiratory diseases
- Suicide and Self-Harm Studies
- Forensic Toxicology and Drug Analysis
- Long-Term Effects of COVID-19
- Water Treatment and Disinfection
Carol Davila University of Medicine and Pharmacy
2013-2024
Clinical Emergency Hospital Bucharest
2005-2024
Spitalul Clinic de Urgență pentru Copii Cluj-Napoca
2009-2021
Iuliu Hațieganu University of Medicine and Pharmacy
2019
Spitalului Clinic de Urgență pentru Copii Maria Sklodowska Curie
2014
Background: Exposure to plants accounts for approximately 5% of human poisoning cases reported by poison control centers in North America and Europe. The aim this study was investigate acute plant patients aged 0–18 years admitted a Romanian pediatric center, focusing on epidemiological clinical aspects. Methods: A retrospective observational conducted between 2017 2022, analyzing medical records demographic information, features, biological findings, outcomes. Statistical analysis performed...
This study analyzed the neurological manifestation profiles of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection across pandemic waves in pediatric patients. The collected data on patients aged between 0 and 18 years, diagnosed with SARS-CoV-2 infection, admitted to a tertiary hospital 1 March 2020 28 February 2023. included 1677 Neurological manifestations were noted 10% (n = 168) median age 3.2 years (interquartile range: 1–11.92). significantly associated (p 0.006)...
Background and Objectives: Our quality management project aims to decrease by 20% the number of neonates with respiratory distress undergoing chest radiographs as part their diagnosis monitoring. Materials Methods: This was developed at Life Memorial Hospital, Bucharest, between 2021 2023. Overall, 125 patients were included in study. The consisted a training phase, then an implementation final results measured one year after end phase. imaging protocol performance lung ultrasounds all on...
<title>Abstract</title> Purpose This study analyzed the neurological manifestation profiles of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection across pandemic waves in pediatric patients. Methods retrospective data patients aged 0–18 years who were diagnosed with SARS-CoV-2 and admitted to a tertiary hospital between March 1, 2020, February 28, 2023. The presence manifestations was established based on symptoms noted each patient chart. relationships or age groups...
The immune system of a child has degree immaturity that is maintained until 6-7 years age. Immaturity may be due to age-related functional disorders in the response. A healthy can contract series infections which contribute maturation during pre-pubertal period. If repeated with prolonged or severe complications occur childhood, presence an immunodeficiency should then considered. Much more frequent than primary are recurrent (frequently involving upper respiratory tract), less and under...
The use of disinfectants, particularly those containing quaternary ammonium compounds (QUACs), has dramatically escalated globally since the coronavirus disease 2019 pandemic. We report a case that highlights risks associated with ingestion low-concentration QUACs solution and emphasizes importance effective management in resolving severe lesions without sequelae. A 17-month-old boy experienced respiratory failure after ingesting disinfectant benzalkonium chloride (BAC). child was initially...
The use of disinfectants, particularly those containing quaternary ammonium compounds (QUACs), has dramatically escalated globally since the coronavirus disease 2019 pandemic. We report a case that highlights risks associated with ingesting low-concentration QUAC solutions and emphasize importance effective management in resolving severe lesions without sequelae. A 17-month-old boy experienced respiratory failure after disinfectant benzalkonium chloride (BAC). child was initially treated at...
This six-year multicentre study investigated acute intentional poisoning with substances of abuse in adolescents to identify changes and patterns substance use. Data from 568 were collected three paediatric poison centres Romania between January 2017 December 2022. The analysed the epidemiological sociodemographic characteristics adolescents, including age, gender, place residence, history abuse, psychiatric history, institutionalized care. findings revealed that cannabis new psychoactive...
Most cases of envenomation by common European vipers (Vipera berus) have not been reported to neurotoxic manifestations. However, these manifestations demonstrated in some subspecies V. berus, found the Carpathian Basin region south-eastern Europe. Here, we report case a 5-year-old girl from south Romania who presented symptoms neurotoxicity, as well other systemic and local symptoms, after being bitten an adder berus subspecies. Treatment consisted monovalent antivenom, corticosteroid,...
Acute liver failure (ALF) is a syndrome defined by jaundice, coagulopathy (INR > 1.5) and hepatic encephalopathy in patients with no evidence of prior disease. Toxins drugs are frequent cause ALF children.The aim our study was to establish the causes toxic children followed up hospital period January 2000 August 2018. We retrospectively studied all records who developed after mushroom/drug exposure had been admitted hospital, main pediatric toxicology center north-western Romania.In last 18...
Objectives: In children, acute liver failure (ALF) is a severe condition with high mortality. As some patients need transplantation (LT), it essential to predict the fatal evolution and refer them early for LT if needed. Our study aimed evaluate prognostic criteria scores assessing outcome in children ALF. Methods: Data of 161 ALF (54.66% female, mean age 7.66 ± 6.18 years) were analyzed based on final (32.91% or LT) etiology. We calculated first day hospitalization PELD score (109...
The purpose was to identify rapidly the etiology of toxic coma in children, appreciate severity coma, detect elements gravity based on associated clinical signs and symptoms evaluate initial treatment. Toxic is a medical emergency, especially Pediatric Emergency Department, requiring rapid precise evaluation. key objectives evaluation management children are: detecting characteristics, depth specific symptoms, etiological differential diagnostic also initializing supportive therapy This...
In this paper we report a scoring system to predict whether patient intoxicated with cardiotoxic substances will require vasopressor inotropic support (VIS) during hospitalization. This new methodology is based on statistics study that analyzes several characteristics of the upon admission and identifies those are correlated VIS necessity. The selected items then used in multi-criteria analysis compute score for each patient, regarding his risks VIS.
Objective: Coughing is a common symptom in the pediatric population. The wide variety of preparations available pharmacies allows easy access to over-the-counter use. Dextromethorphan inhibits cough reflex through an antagonistic mechanism at NMDA-glutamate opioid receptor. Its effects are similar those drugs abuse (phencyclidine and ketamine). In high doses, it produces tachycardia, hypertension, altered consciousness coma, neurological symptoms (agitation, hallucinations, seizures)....
Introduction The epidemiological and clinical characteristics of acute poisoning with liquid laundry detergent capsules have been comprehensively reported. However, studies laboratory test results in these exposures are uncommon. This study analyzed the impact ingestion on admission tests paediatric patients.
This six-year multicentre study investigated acute intentional poisoning with substances of abuse in adolescents to identify changes and patterns substance use. Data from 562 were collected three paediatric poison centres Romania between January 2017 December 2022. analysed the epidemiological sociodemographic characteristics adolescents, including age, gender, place residence, history abuse, psychiatric history, institutionalised care. The findings revealed that cannabis new psychoactive...
REZUMATIntroducere.Alergia alimentară este în creștere la nivel global, majoritatea având debutul cel mai frecvent primii ani de viață.Alergia proteinele din laptele vacă (APLV) reprezintă principala formă alergie sugar.Manifestările clinice ale APLV sunt nespecifice și pot fi cutanate, digestive, respiratorii sau sistemice.Gold standardul diagnostic testul provocare orală, iar dieta excludere a alimentului alergizant tratamentul alergiei.Material metodă.În perioada iunie 2014-decembrie...
Baclofen is a structural analogue of gamma-aminobutyric acid with central myorelaxant effect.Ingestion toxic dose baclofen induces clinical presentation neurological, cardiac, respiratory and metabolic expression, sometimes life-threatening.The authors present the case 17-year old teenage girl who developed deep coma, sinus bradycardia, fi rst-degree atrioventricular block, arterial hypertension hyperglycemia after ingesting large baclofen.The patient was successfully treated supportive...
Test de stress rénal avec la charge d'eau salée et son association le déclin du débit filtration glomérulaire estimé chez les patients maladie rénale chronique en stade 1-3 L'objectif l'étude.Le groupe KDIGO propose DFGe l'albuminurie pour évaluer risque combiné des résultats cliniques.Cependant, peut varier indépendamment base.On a eu but d'améliorer l'efficacité pronostic à l'aide nouveaux facteurs pronostiques significatifs progression détectés pendant test via une 0,5% solution chlorure...